THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY <sup>60</sup>Co GAMMA-RAYS

Bai Yushu; Zhang Xiuxia; Guan Shurong; Wu Hong

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THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS

更新时间：2023-04-23

- THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS
- Journal of Radiation Research and Radiation Processing Vol. 9, Issue 3, Pages: 182-185(1991)
- 作者机构：
  
  1.卫生部工业卫生实验所，北京
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Bai Yushu, Zhang Xiuxia, Guan Shurong, et al. THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS. [J]. Journal of Radiation Research and Radiation Processing 9(3):182-185(1991)
DOI：

Bai Yushu, Zhang Xiuxia, Guan Shurong, et al. THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS. [J]. Journal of Radiation Research and Radiation Processing 9(3):182-185(1991) DOI：

摘要

每日给家兔一次全身照射1 Gy ,60,Co γ线，共4日，总剂量4 Gy。照前和每次照射后检查微核。在分次和一次照射后，微核率随剂量增加而增加，大部分相应剂量点一次照射高于分次照射。当4 Gy时，二者差异有非常显著性（P,<,0.01）。曲线拟合表明，一次照射的微核率适于二次多项式（,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649881&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649885&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649897&type=,），分次照射的微核率适于纯二次式（,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649900&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649902&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649901&type=,）。

Abstract

The changes in the frequencies of micronuclei in CB cells were observed after irradiations of rabbits exposed to single or fractionated wholebody ,60,Co γ-rays. The frequencies of micronuclei showed a increase with the doses. At the same doses micronucleus frequencies in wholebody irradiations were higher than those in fractionated irradiations. The differences between them were very significant at 4 Gy dose. Micronucleus frequencies in single irradiations gave the best to the second degree polynomial model (,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649903&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649905&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649904&type=,), but micronucleus frequencies in fractionated irradiations gave the best to the quadratic equation (,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649907&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649921&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649920&type=,).

关键词

分次照射家兔微核胞质分裂阻断法松胞素-B

Keywords

Fractionated irradiationsRabbitMicronucleiCytokinesis-block methodCytochalasin-B

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School of Radiation Medicine and Public Health, Suzhou University

Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection

Shanghai Institute of Applied Physics, Chinese Academy of Sciences

Institute of Radiation Medicine, Fudan University

Department of Occupational Health, The 3rd Military Medical University

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THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY 60Co GAMMA-RAYS

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摘要

Abstract

关键词

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THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS