EFFECTS OF RADIATION ON LIPID PEROXIDES AND PROTEINS IN RATS AND ANTI-LPO EFFECTS OF TANNIC ACID AND SQUALENE

Wang Chongdao; Lao Qinhua; Qiang Yizhong; Shen Weiming

您当前的位置：

首页 >

文章列表页 >

EFFECTS OF RADIATION ON LIPID PEROXIDES AND PROTEINS IN RATS AND ANTI-LPO EFFECTS OF TANNIC ACID AND SQUALENE

更新时间：2023-04-23

- EFFECTS OF RADIATION ON LIPID PEROXIDES AND PROTEINS IN RATS AND ANTI-LPO EFFECTS OF TANNIC ACID AND SQUALENE
- Journal of Radiation Research and Radiation Processing Vol. 11, Issue 1, Pages: 49-52(1993)
- 作者机构：
  
  1.苏州医学院，苏州　215007
- 作者简介：
- 基金信息：
- DOI：
  CLC：
扫描看全文
Wang Chongdao, Lao Qinhua, Qiang Yizhong, et al. EFFECTS OF RADIATION ON LIPID PEROXIDES AND PROTEINS IN RATS AND ANTI-LPO EFFECTS OF TANNIC ACID AND SQUALENE. [J]. Journal of Radiation Research and Radiation Processing 11(1):49-52(1993)
DOI：

Wang Chongdao, Lao Qinhua, Qiang Yizhong, et al. EFFECTS OF RADIATION ON LIPID PEROXIDES AND PROTEINS IN RATS AND ANTI-LPO EFFECTS OF TANNIC ACID AND SQUALENE. [J]. Journal of Radiation Research and Radiation Processing 11(1):49-52(1993) DOI：

摘要

采用改良的TBA比色法测定组织中的脂质过氧化物（LPO）。结果表明：（1）Th（NO,3,）,4,内照射后第15d时，小鼠肝、脾、肾和骨髓中的LPO含量明显升高，而组织中的蛋白质却明显降低，两者呈负相关；（2）γ线整体照射（2—4 Gy）后72 h，小鼠肝、脾和肾中的LPO含量随着剂量的增加而升高。辐射剂量与LPO含量之间呈现显著线性关系；（3）单宁酸与鲨烯有抗脂质过氧化作用。

Abstract

Lipid peroxides (LPO) in the tissues of mice was determenined by the modified spectrophotometry with TBA. The results showed: 1) LPO contents in liver, spleen, kidney and bone marrow of mice dramatically increased and their proteins markedly reduced at the 15 th day after internal radiation. There exists negative relationship between them. 2) A gradual increase of LPO contents in liver, spleen and kidney of mice at the 72 th hour was followed by an increase of whole-body gamma radiation at a dose from 2 to 4 Gy. A linear relationship between the dose and LPO contents was observed in the dose range of 0—4 Gy. 3) Tannic acid and squalene had certain anti-LPO effects.

关键词

γ辐射脂质过氧化物小鼠单宁酸鲨烯比色法

Keywords

γ-RadiationLipid peroxidesMouseTannic acidSqualeneSpectrophotometry

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of electromagnetic pulses on the expression of occludin in testis of mice

The effects of electromagnetic pulses on the expression of TGF-βs in testis of mice

The irradiation damage of mice induced by internal tritium oxide

Expression of calcium-binding protein S100A8 in bone marrow cells of mice with radiation injury and it’s effect

Effect of irradiation with ¹²C⁶⁺ ions on space memory of mouse brain

Related Author

No data

Related Institution

Department of Histology and Embryology, Fourth Military Medical University

Department of Radiation Medicine, Fourth Military Medical University

Department of Dentistry and Clinical Medicine; Fourth Military Medical University

Shanghai Institute of Applied Physics, Chinese Academy of Sciences

Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection

⁰