LEVEL OF MALONDIALDEHYDE IN TISSUES AND SERUM OF IRRADIATED MICE

Du Zeji; Sun Guoqi; Su Liaoyuan

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LEVEL OF MALONDIALDEHYDE IN TISSUES AND SERUM OF IRRADIATED MICE

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- LEVEL OF MALONDIALDEHYDE IN TISSUES AND SERUM OF IRRADIATED MICE
- Journal of Radiation Research and Radiation Processing Vol. 11, Issue 4, Pages: 227-230(1993)
- 作者机构：
  
  1.苏州医学院，苏州　215007
- 作者简介：
- 基金信息：
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Du Zeji, Sun Guoqi, Su Liaoyuan. LEVEL OF MALONDIALDEHYDE IN TISSUES AND SERUM OF IRRADIATED MICE. [J]. Journal of Radiation Research and Radiation Processing 11(4):227-230(1993)
DOI：

Du Zeji, Sun Guoqi, Su Liaoyuan. LEVEL OF MALONDIALDEHYDE IN TISSUES AND SERUM OF IRRADIATED MICE. [J]. Journal of Radiation Research and Radiation Processing 11(4):227-230(1993) DOI：

摘要

采用荧光分光光度法测定了小鼠组织和血清中丙二醛的含量变化。①3.0 Gy照射后12—24 h时，丙二醛含量最高，随后逐渐下降；②不同剂量（0—4.0 Gy）照射后24 h时，丙二醛含量和照射剂量呈正相关，即丙二醛的含量可很好地反映出机体的损伤情况；③Vit E对辐照后小鼠氧化损伤具有保护作用，250 µg/g重体的Vit E用量是抗氧化作用的最佳用量。

Abstract

The fluorospectrophotometric measurement was used to determine changes of malondialdehyde (MDA) level in mice tissues and serum after irradiation, and to assess the protective effect of Vitamin E on damage induced by free radicals. The results indicated: 1. The highest MDA level took place at 24 h after 3.0 Gy irradiation; 2. MDA level in tissues and serum was better elevated with the increase of irradiation dose; 3. Vit E had a effect on reducing MDA level, the most suitable dose of Vit E is 250 µg/g body weight of mice.

关键词

辐射组织丙二醛维生素E

Keywords

IrradiationTissueMalondialdehydeVitamin E

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