EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED

Liu Weihong; Li Xiuyi; Liu Shuzheng

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EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED

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- EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED
- Journal of Radiation Research and Radiation Processing Vol. 12, Issue 2, Pages: 75-78,108(1994)
- 作者机构：
  
  1.白求恩医科大学放射生物教研室，长春　130021
- 作者简介：
- 基金信息：
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Liu Weihong, Li Xiuyi, Liu Shuzheng. EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED. [J]. Journal of Radiation Research and Radiation Processing 12(2):75-78,108(1994)
DOI：

Liu Weihong, Li Xiuyi, Liu Shuzheng. EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED. [J]. Journal of Radiation Research and Radiation Processing 12(2):75-78,108(1994) DOI：

摘要

观察了单次小剂量X射线全身照射后C 57 BL/6小鼠胸腺细胞IL-1反应性和脾细胞IL-2反应性的变化。发现在100 mGy以内的小剂量照射后，整个胸腺和脾脏的细胞数趋于增多，胸腺细胞对IL-1的反应性和脾细胞对IL-2的反应性趋于增强，体外照射IL-2依赖株CTLL-2细胞亦出现同样的反应趋势，但统计学处理与对照组比较均无明显差异。

Abstract

The changes of reactivities of thymocyte to IL-1 and splenocyte to IL-2 were studied in C 57 BL/6 mice after whole body X-irradiation with low doses. It was found that the number of thymocyte and splenocyte was increased, the reactivities of thymocyte to IL-1 and splenocyte to IL-2 also showed a tendency to increase after X-irradiation with low doses below 100 mGy, but the increase was statisticaly not significant. There was a same effect of low dese radiation on the CTLL-2, growing dependent on IL-2, irradiated in vitro.

关键词

小剂量辐射白介素1白介素2CTLL-2细胞

Keywords

Low dose radiationInterleukin-1 (IL-1)Interleukin-2(IL-2)CTLL-2 cell

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