CROSS-SECTIONS FOR THE INACTIVATION OF ENZYMES AND VIRUSES BY ENERGETIC HEAVY IONS

Zhang Chunxiang

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CROSS-SECTIONS FOR THE INACTIVATION OF ENZYMES AND VIRUSES BY ENERGETIC HEAVY IONS

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- CROSS-SECTIONS FOR THE INACTIVATION OF ENZYMES AND VIRUSES BY ENERGETIC HEAVY IONS
- Journal of Radiation Research and Radiation Processing Vol. 13, Issue 2, Pages: 84-90(1995)
- 作者机构：
  
  1.中山大学物理系，广州　510275
- 作者简介：
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Zhang Chunxiang. CROSS-SECTIONS FOR THE INACTIVATION OF ENZYMES AND VIRUSES BY ENERGETIC HEAVY IONS. [J]. Journal of Radiation Research and Radiation Processing 13(2):84-90(1995)
DOI：

Zhang Chunxiang. CROSS-SECTIONS FOR THE INACTIVATION OF ENZYMES AND VIRUSES BY ENERGETIC HEAVY IONS. [J]. Journal of Radiation Research and Radiation Processing 13(2):84-90(1995) DOI：

摘要

用幂函数电子射程-能量经验公式推导出的径向剂量分布公式计算病毒和酶的重离子失活截面，计算中把这些生物样品看作是一次击中探测器，并认为在相同剂量下,δ,射线和γ射线对生物样品有相同的失活几率，因此，失活几率的径向积分便可计算得出失活截面。用调整参数D-37使计算的截面尽可能与实验数据相符合的方法，对生物样品的72个截面进行了计算。截面的计算值和实验值的比值的平均值和标准误差为0.96±0.11,而D,37,与D,r,37,比值为1.07±0.18，得出了与实验较符合的结果。

Abstract

The calculation of the cross-sections for the inactivation of enzymes and viruses has been made, assuming these to be 1-hit detectors. The calculation makes use of a power-law empirical formula for the radial distribution of dose about the path of an energetic heavy ion. The calculation is made by assuming that the probability of inactivatinga molecular target by irradiation with a given dose of delta rays is equal to the probability of inactivating it with the same dose of gamma-rays. The cross-section is found by adjusting the assumed value of the D,37, dose of gamma-rays until an optimal fit of the calculation to the measured cross-sections is obtained. Taking all 72 cross-section measurements into account, the average ratio of experimental to calculated cross-sections is 0.96±0.11, while the average ratio of the experimental to the fitted value of the gamma-ray D,37, dose is 1.07±0.18.

关键词

重离子剂量分布失活截面病毒酶

Keywords

Heavy ionDose distributionInactivation cross-sectionVirusesEnzymes

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