THE EFFECT OF ARA-C ON THE RECOVERY FROM <sup>60</sup>CO γ-RAYS INDUCED POTENTIALLY LETHAL DAMAGE IN V79 CELLS

Ding Li; Jin Yizun; Cai Rongmei; Shen Zhifen; Xu Liming; Yang jiakuan; Zheng Xiulong

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THE EFFECT OF ARA-C ON THE RECOVERY FROM ⁶⁰CO γ-RAYS INDUCED POTENTIALLY LETHAL DAMAGE IN V79 CELLS

更新时间：2024-11-05

- THE EFFECT OF ARA-C ON THE RECOVERY FROM ⁶⁰CO γ-RAYS INDUCED POTENTIALLY LETHAL DAMAGE IN V79 CELLS
- Journal of Radiation Research and Radiation Processing Vol. 9, Issue 2, Pages: 99-102(1991)
- 作者机构：
  
  1.上海医科大学放射医学研究所，上海
  2.第二军医大学，上海
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1991-05，
  
  Received：19 February 1990，
- 稿件说明：
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Ding Li, Jin Yizun, Cai Rongmei, et al. THE EFFECT OF ARA-C ON THE RECOVERY FROM ⁶⁰CO γ-RAYS INDUCED POTENTIALLY LETHAL DAMAGE IN V79 CELLS. [J]. Journal of Radiation Research and Radiation Processing, 1991,9(2):99-102.
DOI：

Ding Li, Jin Yizun, Cai Rongmei, et al. THE EFFECT OF ARA-C ON THE RECOVERY FROM ⁶⁰CO γ-RAYS INDUCED POTENTIALLY LETHAL DAMAGE IN V79 CELLS. [J]. Journal of Radiation Research and Radiation Processing, 1991,9(2):99-102. DOI：

摘要

本文报道DNA修复抑制剂阿糖胞苷（ara-C）对坪期V 79细胞受

Co γ射线照射后潜在性致死损伤修复（PLDR）的作用。实验结果表明无毒剂量（0.1 µg/ml）和ID

（0.5 µg/ml）的阿糖胞苷对V 79细胞在受10、12 Gy γ射线照射后2、4和6 h的PLDR有一定的抑制作用，它们的修复抑制系数（RIF）在1.15—1.83之间。

Abstract

In this paper

it reported the effect of a DNA repair inhibitor —ara-C on the recovery of plateau phase cultures of V79 cells from

Co γ-rays induced potentially lethal damage (PLDR). The results showed the inhibition of PLDR

while treated with nontoxic dose (0.1 µg/ml) and ID

(0.5 µg/ml) of ara-C for 2

6 hours following 10

12Gy of irradiation

was not very effective. The repair inhibition factors (RIF) ranged from 1.15—1.83.

关键词

阿糖胞苷潜在性致死损伤修复（PLDR）修复抑制系数（RIF）V79细胞

Keywords

Ara-CPotentially lethal damage recovery (PLDR)Repair inhibition factor (RIF)V79 cells

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⁰

THE EFFECT OF ARA-C ON THE RECOVERY FROM 60CO γ-RAYS INDUCED POTENTIALLY LETHAL DAMAGE IN V79 CELLS

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Abstract

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THE EFFECT OF ARA-C ON THE RECOVERY FROM ⁶⁰CO γ-RAYS INDUCED POTENTIALLY LETHAL DAMAGE IN V79 CELLS