Role of Tspan4-mediated migrasomes in the heavy ion radiation effects on lung cancer cells

MA Lijuan; HUANG Yali; WU Qingfeng; DU Yarong; WANG Jufang

doi:10.11889/j.1000-3436.2025-0060

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Role of Tspan4-mediated migrasomes in the heavy ion radiation effects on lung cancer cells

RADIOBIOLOGY AND RADIOMEDICINE | 更新时间：2025-12-29

- Role of Tspan4-mediated migrasomes in the heavy ion radiation effects on lung cancer cells
- “In the field of tumor microenvironment regulation, research has revealed that Tspan4 deficiency enhances the effect of heavy ion radiation, providing a new theoretical basis for targeted "migratory body combined with heavy ion radiotherapy".”
- Journal of Radiation Research and Radiation Processing Vol. 43, Issue 6, Pages: 38-46(2025)
- 作者机构：
  
  1.中国科学院近代物理研究所甘肃省空间辐射生物学重点实验室兰州 730000
  2.中国科学院大学北京 101408
  3.西北师范大学生命科学学院兰州 730000
- 作者简介：
  
  MA Lijuan (female) was born in March 2000, and obtained her bachelor's degree from Northwest Normal University in 2022. Now she is a doctoral student at the Institute of Modern Physics, Chinese Academy of Sciences
  DU Yarong, associate professor, E-mail:duyrlive@impcas.ac.cn
  WANG Jufang, professor, E-mail: jufangwang@impcas.ac.cn
- 基金信息：
  
  Science and Technology Research Project of Chengguan District, Lanzhou City(2024-11-4);National Natural Science Foundation of China(12175289)
- DOI：10.11889/j.1000-3436.2025-0060
  CLC： R815.6
- Received：16 July 2025，
  
  Revised：2025-08-19，
  
  Accepted：19 August 2025，
  
  Published：20 December 2025
- 稿件说明：
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马丽娟, 黄雅丽, 吴庆丰, 等. Tspan4介导的迁移体在肺癌细胞重离子辐射效应中的作用[J]. 辐射研究与辐射工艺学报, 2025, 43(6): 060301.

MA Lijuan, HUANG Yali, WU Qingfeng, et al. Role of Tspan4-mediated migrasomes in the heavy ion radiation effects on lung cancer cells[J]. Journal of Radiation Research and Radiation Processing, 2025, 43(6): 060301.
马丽娟, 黄雅丽, 吴庆丰, 等. Tspan4介导的迁移体在肺癌细胞重离子辐射效应中的作用[J]. 辐射研究与辐射工艺学报, 2025, 43(6): 060301. DOI： 10.11889/j.1000-3436.2025-0060. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0060.

MA Lijuan, HUANG Yali, WU Qingfeng, et al. Role of Tspan4-mediated migrasomes in the heavy ion radiation effects on lung cancer cells[J]. Journal of Radiation Research and Radiation Processing, 2025, 43(6): 060301. DOI： 10.11889/j.1000-3436.2025-0060. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0060.

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Role of Tspan4-mediated migrasomes in the heavy ion radiation effects on lung cancer cells

DOI：10.11889/j.1000-3436.2025-0060