To improve biological output, sugar Brix and resistance to adversities, the dry seeds of Sweet Sorghum, "BJ0601" and "BJ0602" ,were irradiated by ,12,C,+6, ion beam offered by Heavy Ion Accelerator in Lanzhou with different doses. The current results showed as follows: (1) The survival fraction of sweet sorghum presented "saddle like model" that the survival rate decrease, then increase and decrease further again with increase of irradiation doses; (2) Compared with the control, the stalk output per mu (667 m,2,) and sugar Brix showed obvious changes with the changes of irradiation doses; (3) Mutational spectra, including plant height, stem weight per plant, stalk diameter, sugar Brix, early maturity, were selected after irradiation. Based on these results, further studies of the variety breeding and mutation mechanism are needed.