25MeVX射线诱发人淋巴细胞染色体畸变剂量效应和相对生物效应（RBE）

王正明; 候祖洪

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25MeVX射线诱发人淋巴细胞染色体畸变剂量效应和相对生物效应（RBE）

研究论文与科研成果报告 | 更新时间：2023-04-23

- 25MeVX射线诱发人淋巴细胞染色体畸变剂量效应和相对生物效应（RBE）
- DOSE-RESPONSE RELATION OF LYMPHOCYTES CHROMOSOME ABERRATIONS IN HUMAN BLOOD IN VITRO AFTER IRRADIATION WITH 25Mev X-RAYS AND ITS RELATIVE BIOLOGICAL EFFECTIVENESS (RBE)
- 辐射研究与辐射工艺学报 1984年2卷第1期页码：46-50
- 作者机构：
  
  1.湖北省医学科学院
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王正明, 候祖洪. 25MeVX射线诱发人淋巴细胞染色体畸变剂量效应和相对生物效应（RBE）[J]. 辐射研究与辐射工艺学报, 1984,2(1):46-50.

Wang Zhengming, Hou Zuhong. DOSE-RESPONSE RELATION OF LYMPHOCYTES CHROMOSOME ABERRATIONS IN HUMAN BLOOD IN VITRO AFTER IRRADIATION WITH 25Mev X-RAYS AND ITS RELATIVE BIOLOGICAL EFFECTIVENESS (RBE)[J]. Journal of Radiation Research and Radiation Processing, 1984,2(1):46-50.
王正明, 候祖洪. 25MeVX射线诱发人淋巴细胞染色体畸变剂量效应和相对生物效应（RBE）[J]. 辐射研究与辐射工艺学报, 1984,2(1):46-50. DOI：

Wang Zhengming, Hou Zuhong. DOSE-RESPONSE RELATION OF LYMPHOCYTES CHROMOSOME ABERRATIONS IN HUMAN BLOOD IN VITRO AFTER IRRADIATION WITH 25Mev X-RAYS AND ITS RELATIVE BIOLOGICAL EFFECTIVENESS (RBE)[J]. Journal of Radiation Research and Radiation Processing, 1984,2(1):46-50. DOI：

摘要

本文应用25MeV X射线以不同剂量照射人离体血，诱发淋巴细胞染色体畸变。实验共分析了中期分裂相淋巴细胞4769个。观察到各类染色体畸变适于配不同模式，双着丝粒体，和双着丝粒体+着丝粒环最适于配二次多项方程,Y,=,bD,+,cD,2,；与,60,Co γ射线比较，相对生物效应RBE值为0.83。

Abstract

25MeV X -rays were used to induce the lymphocytic chromosome aberration in human blood in vitro. 4769 metaphase lymphocytes were analysed. It has been found that the chrcmosome aberraticn yields conform to different models. The dicentric, and dicentric plus centric ring gave the best fit to the quadratic function ,Y, = ,bD, + ,cD,2,. The RBE of 25MeV X-rays compared with ,60,Co γ rays is clcse to 0.83.

关键词

25 MeV X射线离体人血淋巴细胞染色体畸变双着丝粒体着丝粒环无着丝粒断片二次多项方程直线回归方程相对生物效应

Keywords

25MeV X-rayChromosome aberrations in human blood in vitrcDicentricCentric ringAcentric fragmentThe quadratic functionA linear regression equationThe relative biological effectiveness(RBE)

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