Zhang Hongyuan, Wang Lanjin, Fan Zhengping, et al. COMBINED CYTOGENECTIC EFFECTS INDUCED BY LOW DOSE γ-RAYS IRRADIATION AND BENZENE IN RABBIT PERIPHERAL BLOOD LYMPHOCYTES AND BRONE MARROW CELLS[J]. Journal of Radiation Research and Radiation Processing, 1993,11(2):107-112.
Zhang Hongyuan, Wang Lanjin, Fan Zhengping, et al. COMBINED CYTOGENECTIC EFFECTS INDUCED BY LOW DOSE γ-RAYS IRRADIATION AND BENZENE IN RABBIT PERIPHERAL BLOOD LYMPHOCYTES AND BRONE MARROW CELLS[J]. Journal of Radiation Research and Radiation Processing, 1993,11(2):107-112.DOI:
The paper reports on the changes of combined cytogenectic effects induced by low dose ,γ, rays irradiation and benzene in rabbit lymphocytes and bone marrow cells. The results were summariyed as fotlows: benzene and γ-rays can induce chromosome aberration and SCE in rabbits. The main aberrant type was chromosome type acentric fragment. Chromosome aberrations in blood lymphocytes were higher than in bone marrow cells. As changes of dose, chromosome aberrations by ,γ,-rays were significatly higher than SCE, but linear relationships of dose and effect were not significantly, contradictorily, SCE induced by benzene were more obvious than chromosome aberrations, moreover, linear dose effect relationships of acentric aberration rate and SCE frequency of lymphocytes were observed. The aberration yield induced by γ-rays can significantly be enhanced by treatment benzene. The combined cytogenetic effect of benzene with radiation could be synergetic mainly in dicentrics plus ring, bing mainly additive in acentrics.