EFFECTS OF LOW DOSE IRRADIATION ON cAMP LEVELS OF PINEAL GLAND IN MICE

LIANG Yan; ZHANG Ming; LIU Shuzheng

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EFFECTS OF LOW DOSE IRRADIATION ON cAMP LEVELS OF PINEAL GLAND IN MICE

更新时间：2023-04-07

- EFFECTS OF LOW DOSE IRRADIATION ON cAMP LEVELS OF PINEAL GLAND IN MICE
- Journal of Radiation Research and Radiation Processing Vol. 17, Issue 2, Pages: 122-124(1999)
- 作者机构：
  
  1.白求恩医科大学神经内分泌研究所　长春　130021
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LIANG Yan, ZHANG Ming, LIU Shuzheng. EFFECTS OF LOW DOSE IRRADIATION ON cAMP LEVELS OF PINEAL GLAND IN MICE. [J]. Journal of Radiation Research and Radiation Processing 17(2):122-124(1999)
DOI：

LIANG Yan, ZHANG Ming, LIU Shuzheng. EFFECTS OF LOW DOSE IRRADIATION ON cAMP LEVELS OF PINEAL GLAND IN MICE. [J]. Journal of Radiation Research and Radiation Processing 17(2):122-124(1999) DOI：

摘要

采用昆明系小鼠，全身照射低剂量X射线，剂量为50～500mGy，剂量率为12.5mGy/min，照射后24h，检测松果腺cAMP含量变化，结果表明50～100mGy X射线全身照射可使松果腺cAMP含量明显升高，其中75mGy组cAMP水平为最高（为假照射组的3.7倍,p,<,0.001）。而高剂量的对比观察1～4Gy照射，松果腺cAMP水平呈降低趋势，其中2、4Gy照射组较假照射组明显减少（,p,<,0.05,p,<,0.01）。

Abstract

To observe the effects of low dose radiation on cAMP levels of pineal gland. We examined the cAMP contents of pineal gland after whole—body irradiation with 50, 75, 100, 200, 500mGy X—ray on Kunming male mice. The results showed that the cAMP levels of pineal gland after WBI with 50~100mGy X—ray in mice was higher than sham irradiation mice, especially, 75mGy group was marked higher than that of sham irradiation group (,p,<,0.001) . Whereas, high dose radiation may reduced to the cAMP levels of pineal gland in mice, among 2、4Gy groups was lower than that of sham irradiation group.

关键词

低剂量辐射松果腺cAMP

Keywords

Low dose radiationPineal glandcAMP

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