In order to test the radiosensitivity of normal skin tissure, we cultured cancer patient's skin tissure fibroblast, Surviving fraction experiment was employed to provide data for understanding of the different radiosensitivity among the cancer patients, Medthod: cancer patient's skin tissure fibroblast were cultured in vitro by the way of tissure attachment, cells wereirradiated by graded doses of γ—ray,cell dose response experiment was used to test the radiosensitivity of cell. Result : Cancer patient's skin fibroblast could be propagated and passaged by the method of culture in vitro. Radiosensitivity are different among the various cancer patient s skin tissure fibroblasts.