OBSERVATION ON THE INCIDENCE OF POLYCHROMATIC ERYTHROCYTES WITH MICRONUCLEI IN THE BONE MARROW OF RATS FED MIXED IRRADIATED FOODS

Yang Jiakuan; Lin Weiqi; Cai Rongmei; Cui Shengqing

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OBSERVATION ON THE INCIDENCE OF POLYCHROMATIC ERYTHROCYTES WITH MICRONUCLEI IN THE BONE MARROW OF RATS FED MIXED IRRADIATED FOODS

更新时间：2023-04-23

- OBSERVATION ON THE INCIDENCE OF POLYCHROMATIC ERYTHROCYTES WITH MICRONUCLEI IN THE BONE MARROW OF RATS FED MIXED IRRADIATED FOODS
- Journal of Radiation Research and Radiation Processing Vol. 4, Issue 4, Pages: 18-22(1986)
- 作者机构：
  
  1.上海医科大学　上海市放射医学研究所
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Yang Jiakuan, Lin Weiqi, Cai Rongmei, et al. OBSERVATION ON THE INCIDENCE OF POLYCHROMATIC ERYTHROCYTES WITH MICRONUCLEI IN THE BONE MARROW OF RATS FED MIXED IRRADIATED FOODS. [J]. Journal of Radiation Research and Radiation Processing 4(4):18-22(1986)
DOI：

Yang Jiakuan, Lin Weiqi, Cai Rongmei, et al. OBSERVATION ON THE INCIDENCE OF POLYCHROMATIC ERYTHROCYTES WITH MICRONUCLEI IN THE BONE MARROW OF RATS FED MIXED IRRADIATED FOODS. [J]. Journal of Radiation Research and Radiation Processing 4(4):18-22(1986) DOI：

摘要

本文用两组辐照饲料对Wistar大鼠进行了110天和150天喂养，观察其骨髓多色性红细胞（PCE）的微核效应。一组为混合辐照饲料组，辐照饲料占80%；另一组为辐照蔬菜组，辐照蔬菜占总饲料的3%，辐照剂量为2 KGy，是实际需要的辐照剂量2倍以上。同时设有普通饲料的阴性对照组，和用环磷酰胺处理或给以全身整体照射的阳性对照组。微核测定采用Giemsa染色法、Harris苏本精复染法和荧光染色法，两批实验均表明，在本实验条件下，不论是喂养混合辐照饲料还是辐照蔬菜，都未见到大鼠骨髓PCE微核细胞率有所增高。

Abstract

This paper deals with the observation of micronuclear incidence in PCE bone marrow of Wistar rats. Two groups of rats were fed irradiated foods for 110 days and 150 days respectively. One was fed irradiated foods, in which irradiated foods occupied 80% of total food. Another was that in which irradiated vegetables being added in 3%. The radiation dosage was 2 kCy (200000 rads) .,In addition, there were negative control rats fed general foods and positive rats treated by cyclophosphamide or whole body irradiation with 2 Gy (200 rads) . In this experiment, Giemsa staining, Harris hemotoxylin restaining and acridine orange fluorescence staining were used. From the results, it was indicated that the incidence of PCE with micronuclei in bone marrow of rats was not increased in the animals feeding mixed irradiated foods or in irradiated vegetables.

关键词

混合辐照饲料辐照蔬菜微核卫生安全性

Keywords

Mixed Irradiated FoodsIrradiated VegetablesMicronucleiWholesomeness

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