The purpose of the present study is to ascertain ,147,Pm retention in organism and its radiogenotoxicological effect through varying intervals of internal exposure. Especially, accumulation of ,147,Pm in testis on induction of chromosome aberrations in germ cells and abnormalities in sperm. Results indicated that after iv ,147,Pm through 50d observation. The retention data in testis were well described by an exponential expression:,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649255&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649263&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649262&type=,Studies indicated that the absorption dose in testis was increased when the internal exposure of ,147,Pm was prolonged. Internal contamination of ,147,Pm can be induced chromosome aberrations in germ cells and abnormalities in sperm. Among the type of chromosome aberrations of spermatogonium induced by ,147,Pm including gap, chromatid breakage, chromosome breakage and translocation, as well as polyploid spermatogonium. The chromosome aberration rates and polyploid cells were elevated when the periods of contamination of ,147,Pm were prolonged. At the same time chromosome fragment and translocations of primary spermatocyte also induced by ,147,Pm. Studies showed that polyvalent of primary spermatocyte were enlarged only through 10 days of ,147,Pm contamination. Abnormalities in sperm induced by ,147,Pm—non-hook sperms were predominant.