RADIOPROTECTIVE EFFECTS OF BACTERIAL SUPEROXIDE DISMUTASE ON MICE

Hu Tianxi

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RADIOPROTECTIVE EFFECTS OF BACTERIAL SUPEROXIDE DISMUTASE ON MICE

更新时间：2023-04-23

- RADIOPROTECTIVE EFFECTS OF BACTERIAL SUPEROXIDE DISMUTASE ON MICE
- Journal of Radiation Research and Radiation Processing Vol. 10, Issue 3, Pages: 138-142(1992)
- 作者机构：
  
  1.华东师范大学，上海
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Hu Tianxi. RADIOPROTECTIVE EFFECTS OF BACTERIAL SUPEROXIDE DISMUTASE ON MICE. [J]. Journal of Radiation Research and Radiation Processing 10(3):138-142(1992)
DOI：

Hu Tianxi. RADIOPROTECTIVE EFFECTS OF BACTERIAL SUPEROXIDE DISMUTASE ON MICE. [J]. Journal of Radiation Research and Radiation Processing 10(3):138-142(1992) DOI：

摘要

本文研究了细菌超氧化物岐化酶（b-SOD）对8 Gyγ射线照射小鼠的辐射防护作用。结果表明，辐照前后注射过b-SOD的小鼠，其存活率分别提高50%和30%。辐照前注射b-SOD还可提高骨髓细胞和脾脏淋巴细胞的DNA合成率；降低细胞膜的脂质过氧化和结构损伤。同时还对b-SOD的辐射防护作用的机理作了讨论。

Abstract

The radioprotective effects of bacterial superoxide dismutase(b-SOD) on the mice irradiated by 8 Gy γ¬ray were investigated. The results showed that when b-SOD was injected before and after irradiation, the surviral fraction of mice is increased 50% and 30% respectively. The former treatment could increase the DNA sythesis of the myeloid cells and spleen's lymphocytes, decrease the LPO of tissue homogenates and the haemolysis of erythrocytes significantly. The mechanism that b-SOD can drop the radiation injury of the mice was discussed.

关键词

γ辐射存活率DNA合成脂质过氧化细菌超氧化物岐化酶

Keywords

γ-radiationSurviral fractionBacterial superoxide dismutase(b-SOD)Radioprotetcive effects

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