EFFECT OF POLYSACCHARIDES OF GINSENG(PSG) ON IMMUNOLOGICAL FUNCTION IN X-IRRADIATED MICE

Tian Shengli; Zhao Yong; Li Jianchao; Zhang Xiaoguang

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EFFECT OF POLYSACCHARIDES OF GINSENG(PSG) ON IMMUNOLOGICAL FUNCTION IN X-IRRADIATED MICE

更新时间：2023-04-23

- EFFECT OF POLYSACCHARIDES OF GINSENG(PSG) ON IMMUNOLOGICAL FUNCTION IN X-IRRADIATED MICE
- Journal of Radiation Research and Radiation Processing Vol. 10, Issue 3, Pages: 160-164(1992)
- 作者机构：
  
  1.白求恩医科大学，长春
- 作者简介：
- 基金信息：
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Tian Shengli, Zhao Yong, Li Jianchao, et al. EFFECT OF POLYSACCHARIDES OF GINSENG(PSG) ON IMMUNOLOGICAL FUNCTION IN X-IRRADIATED MICE. [J]. Journal of Radiation Research and Radiation Processing 10(3):160-164(1992)
DOI：

Tian Shengli, Zhao Yong, Li Jianchao, et al. EFFECT OF POLYSACCHARIDES OF GINSENG(PSG) ON IMMUNOLOGICAL FUNCTION IN X-IRRADIATED MICE. [J]. Journal of Radiation Research and Radiation Processing 10(3):160-164(1992) DOI：

摘要

观察了人参多糖对X射线照射小鼠免疫功能的影响。结果表明，人参多糖组小鼠受一定剂量X射线照射后，脾脏有核细胞数、脾脏淋巴细胞对ConA诱导的增殖反应和ConA诱导脾细胞产生白细胞介素2（IL-2）的能力在不同程度上明显高于对照组。发现在照射后第3d这种现象仍然存在。同时发现，人参多糖组小鼠脾脏NK细胞的活性也明显高于对照组。

Abstract

The effect of PSG injection before X-irradiation on immunological functions was studied. The results showed that the counts of nucleated cell of the spleen, the ConA-induced proliferative reaction of splenocytes and the IL-2 production by sp- lenocytes in irradiated mice in PSG group were higher than those in irradiated mice in control group at a certain dose range of X-rays. This effect still existted in the 3 rd day after irradiation with 2.0 Gy X-rays. It was also showed that NK cell activity in PSG group was higher than that in control group. It might be related to the effect of antitumor of PSG.

关键词

人参多糖脾淋巴细胞增殖反应白细胞介素2NK细胞活性

Keywords

Polysaccharides of GinsengProliferative reaction of lymphocyte of spleenIL-2NK cell activity

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