SOME CHARACTERISTIC OF THE RETENTION, DISTRIBUTION AND INTERNAL DOSES OF <sup>59</sup>Fe IN RATS

Wang Deheng; Tian Wuxun; Zhang Hongyuan; Wen Quanfa; Hu Yuexin; Zhao Shanyin

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SOME CHARACTERISTIC OF THE RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁵⁹Fe IN RATS

更新时间：2023-04-23

- SOME CHARACTERISTIC OF THE RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁵⁹Fe IN RATS
- Journal of Radiation Research and Radiation Processing Vol. 11, Issue 2, Pages: 75-79(1993)
- 作者机构：
  
  1.海军医学研究所，上海　200433
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Wang Deheng, Tian Wuxun, Zhang Hongyuan, et al. SOME CHARACTERISTIC OF THE RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁵⁹Fe IN RATS. [J]. Journal of Radiation Research and Radiation Processing 11(2):75-79(1993)
DOI：

Wang Deheng, Tian Wuxun, Zhang Hongyuan, et al. SOME CHARACTERISTIC OF THE RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁵⁹Fe IN RATS. [J]. Journal of Radiation Research and Radiation Processing 11(2):75-79(1993) DOI：

摘要

经胃灌入后，,59,Fe在大鼠内的整体滞留，能很好地拟合二项指数方程。幼年组与成年组的慢组分生物半排期，分别为95 d及109 d，无统计学显著性差别。,59,Fe的主要分布器官是肝与骨髓。,59,Fe在器官中的滞留方程为一项或二项指数式。在幼年组多数器官中，,59,Fe排出比成年组快。幼年组的剂量特点是多数器官总累积剂量较大，剂量累积速度较快。口服同量的,59,Fe，对幼年鼠有较大生物效应。

Abstract

After gastric intubation, the whole body ,59,Fe-retentions in rats were fit to two compartment exponential equations. The biological half lifes for ,59,Fe in the slow compartment are 95 and 109 days for young and adult rats respectively, not statistically significantly different. The main ,59,Fe-acculative organs are liver and bone marrow. The biological eliminations of ,59,Fe from most organs in young rats are faster than in adult rats. The young rats get more total accumulative dose in organs except liver and total body and have a faster dose accumulative speed than the adult rats. Equal quantities of ,59,Fe P. O. may probably give young rats more intensive biological effects than adult rats.

关键词

59Fe滞留分布内剂量大鼠

Keywords

59FeRetentionDistributionInternal doseRat

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Second Affiliated Hospital, Suzhou University

Department of Radiation Medicine, Faculty of Military Prevention Medicine,Fourth Military Medical University

Electron Microscopic Center, Faculty of Preclinical Medicine,Fourth Military Medical University

School of Radiological Medicine and Public Hhealth, Suzhou University

No.1 Affiliated Hospital, Suzhou University

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SOME CHARACTERISTIC OF THE RETENTION, DISTRIBUTION AND INTERNAL DOSES OF 59Fe IN RATS

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摘要

Abstract

关键词

Keywords

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SOME CHARACTERISTIC OF THE RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁵⁹Fe IN RATS