OBSERVATION OF SYNAPTONEMAL COMPLEX ABERRATIONS IN MALE MICE BY ELECTRON MICROSCOPY

Jiang Jie; Wang Bin; Wang Yamei

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OBSERVATION OF SYNAPTONEMAL COMPLEX ABERRATIONS IN MALE MICE BY ELECTRON MICROSCOPY

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- OBSERVATION OF SYNAPTONEMAL COMPLEX ABERRATIONS IN MALE MICE BY ELECTRON MICROSCOPY
- Journal of Radiation Research and Radiation Processing Vol. 13, Issue 4, Pages: 229-232(1995)
- 作者机构：
  
  1.白求恩医科大学放射医学研究所，长春　130021
  1.东北师范大学生物系，长春　130024
- 作者简介：
- 基金信息：
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Jiang Jie, Wang Bin, Wang Yamei. OBSERVATION OF SYNAPTONEMAL COMPLEX ABERRATIONS IN MALE MICE BY ELECTRON MICROSCOPY. [J]. Journal of Radiation Research and Radiation Processing 13(4):229-232(1995)
DOI：

Jiang Jie, Wang Bin, Wang Yamei. OBSERVATION OF SYNAPTONEMAL COMPLEX ABERRATIONS IN MALE MICE BY ELECTRON MICROSCOPY. [J]. Journal of Radiation Research and Radiation Processing 13(4):229-232(1995) DOI：

摘要

联会复合体和染色体一样，可以显示生殖细胞减数分裂过程中的诱变效应。采用雄性昆明种小鼠为实验材料，经4 Gy X射线照射，于照后不同时间处死小鼠，制备联会复合体标本，并用电镜观察联会复合体畸变。除观察到常规染色体方法所见到的断裂、易位等畸变外；还观察到一些和联会有关的畸变类型，如银染桥、自身回折配对、联会紊乱，并探讨其和染色体畸变的关系，为今后研究生殖胞细遗传物质损伤提供一个新的方法。

Abstract

Synaptonemal complexes revealed mutagen-induced effects in germ cell meiotic chromosomes. Male mice were irradiated by 4 Gy X-rays and spermatocytes were harvested at different time after exposure. Various form of synaptonemal complex aberrations were observed, such as breaks, rings, rearrangement which were consistent with those aberrations observed in metaphase I chromosome by conventional cytogenetic analysis. Some novel forms of synaptonemal complex aberrations were observed. The relationship between synaptonemal complex aberration and chromosome aberration was discussed.

关键词

电离辐射联会复合体畸变染色体畸变

Keywords

Ionizing radiationSynaptonemal complexChromosomeAberration

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