RADIOSENSITIVITIES OF IMMUNE ORGANS' STROMAL PROGENITORS

Yu Hongchen; Zhang Hongmei; Ling Ling; Yu Zhiqiang; Liu Ji

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RADIOSENSITIVITIES OF IMMUNE ORGANS' STROMAL PROGENITORS

更新时间：2023-04-23

- RADIOSENSITIVITIES OF IMMUNE ORGANS' STROMAL PROGENITORS
- Journal of Radiation Research and Radiation Processing Vol. 14, Issue 1, Pages: 59-62(1996)
- 作者机构：
  
  1.白求恩医科大学预防医学院卫生毒理教研室，长春　130021
  1.白求恩医科大学第一临床学院，长春　130021
- 作者简介：
- 基金信息：
- DOI：
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Yu Hongchen, Zhang Hongmei, Ling Ling, et al. RADIOSENSITIVITIES OF IMMUNE ORGANS' STROMAL PROGENITORS. [J]. Journal of Radiation Research and Radiation Processing 14(1):59-62(1996)
DOI：

Yu Hongchen, Zhang Hongmei, Ling Ling, et al. RADIOSENSITIVITIES OF IMMUNE ORGANS' STROMAL PROGENITORS. [J]. Journal of Radiation Research and Radiation Processing 14(1):59-62(1996) DOI：

摘要

用体外液体单层培养技术研究了小鼠胸腺、脾脏和淋巴结成克隆性基质祖细胞（CFU-F）的辐射敏感性：胸腺CFU-F的D,0,值为2.3Gy,n,值为1.5,脾脏为2.8 Gy和1.2；而淋巴结的则为2.7 Gy及1.4。脾致密型CFU-F亚群的D,0,值为2.1 Gy,n,=1.5,而松散型CFU-F亚群的D,0,= 4.4 Gy,n,=1.2。这为大剂量辐射损伤混输基质细胞以提高受体免疫造血功能，提供了实验依据。

Abstract

By using the technics of culture of immuno-stromal progenitors in vitro, we studied their radiosensitivities after irradiation in various doses. The values of D,0, and n of thymus, spleen and lymph node were 2.3 Gy and 1.5, 2.8 Gy and 1.2, 2.7 Gy and 1.4 respectively. The radiosensitivity of the CFU-F subgroups which formed dense colonies was significantly higher than that of loose colonies, when cultured in vitro.

关键词

辐射敏感性细胞存活免疫器官免疫基质祖细胞

Keywords

RadiosensitivitySurvial cellsImmuno organImmuno-stromal progenitors

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