最新刊期
      期 1 ， 1989
      • Wei Kang
        Vol. 7, Issue 1, Pages: 1-4,11(1989)
        摘要：The paper reviews the recent progress in application of molecular biology techniques in the study of radiation biology. The three sections are as follows: (1) the study of DNA damage on molecular level, (2) the molecular mechanism of radiation cell genetics, including chromosome abberation and cell mutation,(3) the study on DNA repair gene with DNA mediated gene transfer techniques.  
        关键词：Molecular biology;Recombinant DNA technique;Gene transfer;DNA damage and repair   
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        发布时间：2023-04-23
      • Luo Yunxia,Li Ping,Pan Hongbin,Yu Min
        Vol. 7, Issue 1, Pages: 5-11(1989)
        摘要：The radiation-induced crosslinking of siloxane copolymers with various contents of vinyl group has been studied. It was found that the existance of vinyl groups in the copolymer macromolecules could reduce the gelation dose and hence increases the G value of crosslinking.The variation of the content of vinyl groups in sol fraction of irradiated samples with dose was followed by NMR. It has been shown that they remain unchanged with radiation dose. Such a result indicates that the vinyl group is very sensitive to radiation-induced crosslinking. The effect of vinyl group on the enhancement of crosslinking could be well understood.When a semi-crystalline copolymer at -78℃ was irradiated such an effect was much pronounced. It results from concentrating of vinyl group in the amorphous region so that greater probability exists in reaction with radical before they decay with a process without crosslinking formation.The vinyl group in siloxane copolymer could also influence the deviation from the linear relationship given by Charlesby and Pinner. The effect of vinyl content on the relationship between crosslinking density and radiation dose is expected to be in a similar situations.  
        关键词：Polysiloxane;Radiation effect;Crosslinking   
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        发布时间：2023-04-23
      • Wu Yiming,Chou Dezen,Zhang Zhiping,Jing Yudong,Ying Shengkang
        Vol. 7, Issue 1, Pages: 12-17(1989)
        摘要：Hydroxy-terminated polybutadiene (HTPB) is one kind of polybutadiene chief chain structure polymer terminated with hydroxyl groups, because there are double-bonds in the chief chain, the α-hydrogen atom is very active, and crosslink reaction is easy to take place under γ-ray irradiation.The property of HTPB is affected by γ-ray directly. So It is significant practically and theoretically to study the change in structure and property under radiation.The microstructure of HTPB solute molecules and the change of molecular weight with radiation dose were studied by infrared spectra, NMR and GPC in our work. The effects of radiation on HTPB were discussed from the viewpoint of the change of solute molecular structure and gel kinetics. The measured gel dose of HTPB is 0.605 MGy, G=1.802, thus we can conclude the crosslink reaction is the chief process in the irradiation of HTPB.  
        关键词：Hydroxy-terminated polybutadiene;Microstructure;Radiation crosslink;Carbon-13 nuclear magnetic reasonance   
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        发布时间：2023-04-23
      • Zhu Bingchai,Chen Tiehe,Lü Jiaben,Wang Zongwu,Wang Lanjiu
        Vol. 7, Issue 1, Pages: 18-23(1989)
        摘要：Rhesus monkeys were irradiated by 60Co γ ray exposure under different conditions, and comparative studies on their chromosome aberrations have been made. The dose rate of single acute irradiation was 223 mGy/min, the dose rate of fractionated cumulative irradiation was 223 mGy/min, and the dose of 0.25 Gy was delivered once a week, the dose rate of chronic continuous irradiation was 0.26 mGy/min for 190 min, 5 days per week. The total cumulative dose for each group was 2.0 Gy.It was found that the types of chromosome aberrations were mainly dicentric aberrations and acentric fragments in single acute irradiation, and acentric fragments in both fractionated cumulative and chronic continuous irradiation groups. The frequencies of chromosome aberrationns in these groups increase linearly with increasing dose. The degree of chromosome damage in single acute irradiation group was much greater than those in the other groups, but degree and characteristics of chromosome damage between fractionated cumulative and chronic comtinuous irradiation groups was not significantly different. Acentric fragments in lymphocyte chromosomes ceased to increase when the cumulated dose in fractionated cumulative or chronic continuous irradiation reached to more than 1.0 Gy. The frequencies of chromosome aberrations basically decreased to control level within a year following the termination of irradiation.  
        关键词：60Co-γ ray;Different irradiation condition;Chromosome aberration;Comparative study   
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        发布时间：2023-04-23
      • Ding Lianzhong,Yu Xingying,Qi Juyue
        Vol. 7, Issue 1, Pages: 24-28(1989)
        摘要：Technical feasibility of irradiation sterilization of pollen by accelerated electron beam was studied in this paper. The irradiation efficacy for the decontamination of pollen was determined.Irradiation effect of electron beam on morphology and composition of pollen was also studied. The photos of morphology were given for pollen irradiated by electron beam with different doses. The dose dependence of the content of pollen composition, such as protein, amino acid, L-ascorbic acid, total ascorbic acid and catalase was determined. The corresponding tests for pollen irradiated by 60Co gamma rays were contrasted. The results show that the irradiation treatment by accelerated electron beam is an effective way for pollen sterilization.  
        关键词：Electron beam;Pollen;Irradiation sterilization   
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        发布时间：2023-04-23
      • Zhou Derong,Meng Haiying,Liu Jinwen
        Vol. 7, Issue 1, Pages: 29-32(1989)
        摘要：The serum LDH and its isoenzymes of 61 medical diagnostic X-rays workers were observed in this paper.The results showed that both total activity of the LDH and LDH3 increased clearly and LDH1 decreased clearly when irradiated geoup compared with control group.Comparing with control group, the LDH1 of both<10 years and 10-20 years of occupatipnal lengh of service groups decreased markedly and LDH3 increased markedly. The LDH1 decreased and LDH3 increased respectively with the length of service within 20 years, and both LDH1 and LDH3 returned to normal level when the length of service was more than 20 years.Total activity of the LDH1 and LDH3 of both 20-50 mGy and> 50 mGy dose group increased markedly and LDH1 decreased clearly when it was compared with control group. The changes of the LDH and its iscenzyme related to cumulative dose. Therefore, we consider that the changes of the LDH and its isoenzyme is a significant parameter to the radiation effect of low-dose.  
        关键词：Medical diagnostic X-rays worker;LDH;Isoenzyme;Radiation effect   
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        发布时间：2023-04-23
      • Lu Shaoping,Yang Fengtong,Xu Chengxiong
        Vol. 7, Issue 1, Pages: 33-38(1989)
        摘要：Hematopoietic residual injury, which is identified by the permanent defect of the blood forming system, could be induced in mice by repeated sublethal 60Co γ-ray exposures. The number of hematopoietic stem cells (CFU-S) in mouse femora could be enhanced to a normal or near normal level if the 3 or 5 doses of 4.0 Gy irradiated mice were treated with a preparation extracted from an edible fungus Tremella Fuciformis Berk (TFP) 2 months after the irradiation. The number of endogenous spleen colonies and the spleen weight also increased markedly after the treatment. Because of the similarity found in the changes of hematopoietic functions between the mice of residual injury and the patients of aplastic anemia, it is suggested that TFP may be useful to the patients of such blood disorder.  
        关键词：Residual radiation injury;Hematopoietic stem cells;Tremella Fuciformis Berk   
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        发布时间：2023-04-23
      • Su Zaozhong,Luo Zuyu
        Vol. 7, Issue 1, Pages: 39-44(1989)
        摘要：The nature of the signal triggering error-prone DNA repair function in mammalian cells was studied from two notions: 1) Does the inducing signal result from the direct hitting the cellular targets by DNA-damaging agents? 2) Is inhibition of DNA replication a prerequisite condition for the triggering effect? Thus, the ultraviolet (UV) -irradiated exogenous DNAs were introduced into human and rat cells by transfection. The results showed that this transfection was able to induce the error-prone repair as efficient as direct UV-irradiation to cells. Moreever, the two inductory treatments expressed similar kinetics and dose-responses. No matter whether the introduced DNAs initiated replication, they exhibited the inductory activity. Therefore, it can be considered that DNA lesions itself, not the direct interaction of DNA-damaging agents with specific cellular targets, serve as a triggering signal for the inductory process. Inhibition of DNA replication is not a prerequisite for the inductory signal.  
        关键词：Error-prone DNA repair;Viral Probe;Inducing signal   
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        发布时间：2023-04-23
      • Zhou Jichun,Zhu Zhenkang,Shi Songyuan,Feng Youfang,Liu Yuming,Zhao Yizheng,Ren Huifang,Chen Xianwei,Zhao Jie,Chen Jiancong,Yin Xiufeng
        Vol. 7, Issue 1, Pages: 45-50(1989)
        摘要：This paper reports the effect of difunctional monomer, diethylene glycol diacrylate (DGDA) on radiation crosslinking of PVC.Crosslinking of PVC proceeds very rapidly during the initial period of irradiation. When the dose reaches 40 kGy, it slows down and the gel content tends to level off. Under the same dose condition, PVC gel content and G value increase with increase of the amount of DGDA.Radiation Crosslinked PVC has a good insulating property and mechanical property.By comparing crosslinked PVC with uncrosslinked PVC, the loss weight after thermal aging of crosslinked PVC has a great decrease. But the tensile strength after aging (K1) and the elongation after aging (K2) of crosslinked PVC have a great increase respectively. It was also found that the heat-resisting property of PVC had been improved after being crosslinked.  
        关键词：Radiation;Radiation crosslinking;Polyvinyl chloride (PVC);Diethylene glycol diacrylate (DGDA);Gel content   
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        发布时间：2023-04-23
      • Wang Weiguo,Gu Yongbao,Li Fengmei,Zhou Ruaying
        Vol. 7, Issue 1, Pages: 51-56(1989)
        摘要：The irradiation technique combined with freezing has been used to control the microorganism in Beijing Roast Duck. Cobal-60 was chosen as γ-ray source. The absorbed dose was 2 kGy on an average. After irradiation, the microbe counts have reached the tolerable. Compared with untreated ducks, the irradiated ones showed no remarkable change in nutrition, chemistry, vitamin etc. It has been proved through tests that the irradiated frozen Beijing Roast Duck is wholesome.  
        关键词：Irradiation;Beijing roast duck;Microorganism;Wholesomeness   
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        发布时间：2023-04-23
      • Ye Shuhua,Wang Xinli,Lu Qihua,Lon Cuihua,Shen Youjun
        Vol. 7, Issue 1, Pages: 57-60(1989)
        摘要：On the basis of the investigation on the role of change of viscosity with radiation, we studied the relationship between viscosity and the properties of blood population. It was found that the viscosity depeneded on the concertration of blood cells. In fact, it concerned blood cells hematocrit and cells electrophoresis on the early period of radiation, especialy erythrocyte electrophorsis. During the sickness, it related to the change of the erythrocyte sedimentation rate. When the mice was irradiafed at 6 Gy, it was concern of erythrocyte defomation. But plasma viscosity is not main factor of blood viscosity.  
        关键词：Micro erythrocyte sedimentation rate;Micro hematocrit;Erythrocyte electrophoresis;Platelet electrophoresis;Erythrocyte defomation   
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        发布时间：2023-04-23
      • Wu Jilan,Pan Xianming,Qi Shengchu,Qu Linbo,Ha Hongfei
        Vol. 7, Issue 1, Pages: 61-64(1989)
        摘要：In the paper, the formation of peroxide has been studied in the liquors and the model systems of ethanol aqueous solution under gamma irradiation. The G values of peroxide in irradiated liqour and ethanol systems have been gotten from the initial linear part of the curve. They are 1.0-3.6 for the different liquors and 3.6 for 60% ethanol aqueous solution respectively. It has been shown that oxygen plays an important role in the formation of peroxide. It has also been found that peroxide is rather stable in some liquors and its content remains higher up to 6-7 ppm after storage of 20 days. So, it is a urgent task to provide a H2O2 safety limit in the irradiated liquors.  
        关键词：Irradiation of liquor;H2O2 and peroxide;Radiolysis of ethanol;Decay rate of peroxide   
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        发布时间：2023-04-23
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