最新刊期
      期 3 ， 1998
      • Xia Shouxuan
        Vol. 16, Issue 3, Pages: 129-134(1998)
        摘要：At subcellular level, the chromosome aberration of human peripheral lymphocytes had been popularly accepted as a useful radiation biodosimeter. But at the molecular level, very good biomarkers which could be used clinically in the estimation of radiation damage were still lacking. In the recent years the gene mutation of blood cells deserved much attention. The radiation induced gene mutation occurred in the genome of hematopoitic stem cells in the bone marrow,but could be estimated in the peripheral blood.Such kind of somatic gene mutation has several merits, such as very stable, high radio-sensitivity, good dose-response relationship, and easy to obtain the assay samples clinically. In this paper, the recent advances in the study of radiation induced mutations of hprt gene, T-cell receptor gene, and human leucocyte antigen-A gene of lymphocytes, and glycophorin A gene of red cell precursors were reviewed,and their biological characteristics, current assay methods,and clinical application were discussed.  
        关键词：Radiation biodosimeter;Somatic gene mutation;HPRT gene;TCR gene;HLA-A gene;Glycophorin A gene;Hematopoitic cells   
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        发布时间：2023-04-18
      • Li Shujun,Sun Weijun,Liu Xiuju,Gao Yongzhong,Li Huisheng,Xie Liqing
        Vol. 16, Issue 3, Pages: 135-140(1998)
        摘要：Ultra high molecular weight polyethylene fibers have been crosslinked by electron beam. The structure and mechanical properties of them have been investigated in different irradiation atmospheres. The obtained results show that the gel content and crosslinking density increase with the increase of dose,the swelling ratio and average molecular weight of crosslinked net decrease with the increase of dose,the tensile strength and failure elongation decrease with the increase of dose,the tensile modulus increases with the increase of dose. When the samples are irradiated in air,vaccum and acetylene atmospheres,the effect of irradiation in acetylene atmosphere is best.  
        关键词：Electron beam;Irradiation crosslinking;Ultra high molecular weight polyethylene fibers;Structure;Mechanical properties   
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        发布时间：2023-04-18
      • Yang Zhongtian,Toshiaki Yagi,Yosuke Morita,Tadao Seguchi
        Vol. 16, Issue 3, Pages: 141-145(1998)
        摘要：Oxygen consumption and carbon dioxide evolution for EPR, PE, PVC and CSM as the cable insulation materials after irradiation and thermal aging were measured by using gas chromatograph in order to study the lifetime prediction. CO2 evolution increases linearly with O2 consumption. The apparent activation energy for these materials varies between 68kJ/mol and 133kJ/mol. Reaction mechanism was discussed.  
        关键词：Polyethylene;Polyvinyl chloride;Ethylene-propylene ruber;Chlorosulfonated polyethylene;Thermal oxidative degradation;Gas chromatography;γ-radiation   
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        发布时间：2023-04-18
      • Qian Suping,Zhang Jiashan,Yao Side,Wang Wenfeng,Lin Nianyun
        Vol. 16, Issue 3, Pages: 146-149(1998)
        摘要：Using pulse radiolysis techniques the reaction rate constants of hydroxy-cinnamic acid derivatives (HCAD) with superoxide radical anion (O2-•) were obtained by competition reaction kinetic analysis. The reacting mechanism was proposed based on the HPLC analysis of final products and UV spectrophotometry.  
        关键词：Hydroxycinnamic acid derivative (HCAD);Pulse radiolysis;Competition reaction kinetic analysis;Final products analysis;Superoxide radical anion   
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        发布时间：2023-04-18
      • Gong Shouliang,Liu Shuchun,Zhang Yingchun,Liu Shuzheng
        Vol. 16, Issue 3, Pages: 150-152(1998)
        摘要：The adaptive response of thymocyte apoptosis and cell cycle progression induced by 75mGy X-rays in mice were observed. The percentages of thymocyte apoptotic bodies (TAB) and cell cycle phase count were examined with flow cytometry. It was found that the percentages of TAB increased,the percentages of S phase cells decreased and the percentages of G0/G1 and G2+M phase cells increased after whole-body irradiation with 1.5 or 2.0Gy in mice,all were significant statistically,as compared with sham-irradiation. When the mice were irradiated with 75mGy (inductive dose,D1) 6h before 1.5 or 2.0Gy (challenge dose, D2) exposure,the damage effects of D2 on thymocyte apoptosis and cell cycle progression were obviously weaked. Low dose radiation may induce the adaptive response of thymocyte apoptosis and cell cycle progression.  
        关键词：Low dose radiation;Adaptive response;Apoptosis;Cell cycle progression   
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        发布时间：2023-04-18
      • Cui Yufang,Yang Hong,Gao Yabing,Xiong Chengqi,Xia Guowei,Wang Dewen
        Vol. 16, Issue 3, Pages: 153-156(1998)
        摘要：Effects of 5-hydroxytraptamine (5-HT) on growth of normal and irradiated NIH/3T3 fibroblasts were observed by using MTT colorimetry,a silver colloid technique of AgNORs, and immunohistochemical methods were used to estimate type III collagen and DNA synthesis. The results showed that,when 5-HT of 2×10-6mol/L was used,the counts of normal and irradiated fibroblasts increased by 1.5 times as many as that of control group; proliferative activity (expressed by OD values) of the fibroblasts were about 1. 3 and 1.6 times that of control value; the number of AgNORs granules elevated to 2.5 times that of control value. In addition,5-HT of 1.0×10-6mol/L also induced the increments of percentage of S-phase fibroblasts and type III collagen positive fibroblasts,both of them were 2.7 and 2.1 times that of control group,respectively.  
        关键词：5-Hydroxytraptamine;Fibroblast;γ-Irradiation;Type III collagen;DNA synthesis   
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        发布时间：2023-04-18
      • Ju Guizhi,Fu Shibo,Liu Jianxiang,Liu Shuzheng
        Vol. 16, Issue 3, Pages: 157-160(1998)
        摘要：In the present study,the effect of X-rays on EL-4 cell doubling time and cell cycle progression were investigated. Cell doubling time in culture was calculated. Propidium iodide (PI) staining and flow cytometer (FCM) were used for cell cycle measurement. The results showed that EL-4 cell doubling time was prolonged significantly after irradiation with doses of 0.5, 1.0,2.0 or 4.0Gy. G1 arrest occurred at 72h after 1.0Gy and at 12h to 72h after 2.0 or 4.0Gy. G2 arrest occurred at 72h after 0.5 or 1.0Gy and at 48h to 72h after 2.0 or 4.0Gy. S phase cells decreased after 1.0,2.0 or 4.0Gy exposure. We concluded that 0.5 to 4. 0Gy X-irradiation could induce G1 and G2 arrest for EL-4 cells,which related closely to cell doubling time prolongation.  
        关键词：X-irradiation;G1 arrest;G2 arrest;Cell doubling time   
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        发布时间：2023-04-18
      • Liu Yongbiao,Su Liaoyuan,Kong Xiangrong
        Vol. 16, Issue 3, Pages: 161-164(1998)
        摘要：The spleen lymphocytes in mice after fraction irradiation were separated into L3T4,Lyt2 and B cells by a panning method with monoclonal antibodies. The effects of elemene on function and regulation of lymphocyte subsets were studied by using 3H-TdR incorporation,the SOD activity and LPO content were measured. The results indicated that elemene could increase the radiation resistance of lymphoicyte subsets,enhance the helping effects of L3T4 on B cell,increase spleen SOD activity and decrease LPO content. The formation of the mechanism of protection may be due to scavenging free radical and relieving the damage of target.  
        关键词：Lymphocyte subsets;Free radical;Peroxidation;γ-ray whole body irradiation;Elemene   
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        发布时间：2023-04-18
      • Xu Yongzhong,Zhao Jingyong,Lao Qinghua
        Vol. 16, Issue 3, Pages: 165-168(1998)
        摘要：With the technique of multinucleus cell and cytokinesis-block micronucleus (CBMN) method, the relationships between mutations at HPRT loci,micronuclei and accumulative doses were analyzed. The results were as follows: On the first day after intravenous injection (accumulative dose 1.73cSv) ,by comparison with the control group, the HPRT mutant frequencies,micronucleus cell frequencies and micronucleus frequencies increased significantly (p<0.01) . There existed a hemilogarithmic linear relationship between mutant frequencies at HPRT loci,micronucleus cell frequencies,micronucleus frequencies and accumulative doses, which could be described by following regression equation: Y=a+b lnX. A good linear relationship between HPRT mutant frequencies and micronucleus frequencies was observed. It is expected that the detection of HPRT locus mutation may soon be used as a biological dosimeter.  
        关键词：Late fission products;HPRT gene mutation;Micronucleus   
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        发布时间：2023-04-18
      • Yin Jinxiang,Liu Guowen,Men Huaidong,Hong Xiaoyin
        Vol. 16, Issue 3, Pages: 169-172(1998)
        摘要：This paper studies on the photosensitive resin of free-radical system used for stereolithography. The effect of the molecule structure, molecule weight, functional group density of the prepolymers and diluent monomers on hardness, flexibility of cured products has been investigated. In addition two kinds of new photosensitive resin with low cost and good preperties have been obtained. This research provides a good basis for application of free-radical photosensitive resin.  
        关键词：Free-radical system;Photosensitive resin;Stereolithography   
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        发布时间：2023-04-18
      • Wang Dehai,Ma Jianhua,Xu Guocai,Jiang Ling
        Vol. 16, Issue 3, Pages: 173-176(1998)
        摘要：Several samples of quartz optical fiber coated with UV-cured epoxy acrylates were analyzed with XPS. The results suggested that the nature of functional group of coating mentioned plays an important part in the change of transmitting property for optical fiber. There exists an obvious influence of -C=O or -O-C=O group on the loss of optical fiber: the more the -C=O or -O-C=O group contained in coating, the greater the loss. On the other hand,the increase of the content of -C-C- group could lead to fewer loss.  
        关键词：Epoxy acrylates;Quartz optical fiber;UV-curable coating;XPS   
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        发布时间：2023-04-18
      • Yi Min,Li Jun,Zhang Jianbo,Wang Weijing
        Vol. 16, Issue 3, Pages: 177-179(1998)
        摘要：Soy-oil fatty acid was used to synthesize the soy-oil fatty acid modified acrylic coating by esterification reaction. After coating and EB curing,the result showed that the properties of the film were excellent,and it was suitable for the coating of wood furniture cured by EB.  
        关键词：Soy-oil fatty acid;Acrylic acid;EB curing   
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        发布时间：2023-04-18
      • Chen Xuming,Jin Yangzhi,He Mingxia
        Vol. 16, Issue 3, Pages: 180-184(1998)
        摘要：In this paper,the linear,branched and BLFG (Branch which coses part of its end Functional Group) PUA (linear PUA includes polyether PUA) were synthesized and their main properties were studied in details. It's shown that the branched PUA has the best mechanical and photosensitive properties, but it's viscosity is very high,while BLFG PUA's viscosity is very low,but its mechanical and photosensitive properties are much worse than the other two's.  
        关键词：Polyester polyurethane acrylate;Photopolymerization;UV curing   
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        发布时间：2023-04-18
      • Zhao Changkuo,Lin Yiqing,Wang Jindi,Qi Guozhen
        Vol. 16, Issue 3, Pages: 185-187(1998)
        摘要：Four photoinitiators of water soluable thioxanthone derivatives were synthesized. 2-hydroxy-3- (1-methyl-9-oxo-9H-thioxanthone-4-yloxy) -N,N,N-rimethyl-l-propanamonium chloride is a new compound which was not reported. These compounds were identified by IR, NMR, MS and Elemental analysis etc. and the UV absorption wavelength and the molar absorption coefficient were determined.  
        关键词：Thioxanthone;Photoinitiator;Watersoluble photoinitiator   
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        发布时间：2023-04-18
      • Yi Jian,Jiang Jiagui,Liu Fenju,Zhu Caiying
        Vol. 16, Issue 3, Pages: 188-189(1998)
        摘要：Anoxia,continual γ-irradiation or anoxia in combination with contiunal γ-irradiation could increase the LPO contents of livers,spleens and hearts of mice. The enhancements of SOD activities of livers, spleens and hearts of mice in anoxia group and γ-irradiation group were observed. Anoxia in combination with continual γ-irradiation could result in the decrease of SOD activities of livers,spleens and hearts of mice.  
        关键词：Anoxia;γ-Irradiation;Mice;Superoxide dismutase (SOD);Lipid peroxide (LPO)   
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        发布时间：2023-04-18
      • Bao Borong,Wu Minghong
        Vol. 16, Issue 3, Pages: 190-192(1998)
        摘要：This paper presents the highlights of IAEA International Symposium on Radiation Technology for Conservation of the Environment,especially in purification of exhaust gases,purification and decontamination of water,reuse and treatment of plastics and solid wastes and preparation of environmental friendly materials. The symposium reflects the new trends in radiation technology for conservation of the environment in the world.  
        关键词：Radiation technology;Conservation of the environment   
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        发布时间：2023-04-18
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