用CB法研究分次照射时微核的剂量效应关系

白玉书; 张秀霞; 关树荣; 巫红

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用CB法研究分次照射时微核的剂量效应关系

更新时间：2023-04-23

- 用CB法研究分次照射时微核的剂量效应关系
- THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS
- 辐射研究与辐射工艺学报 1991年9卷第3期页码：182-185
- 作者机构：
  
  1.卫生部工业卫生实验所，北京
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白玉书, 张秀霞, 关树荣, 等. 用CB法研究分次照射时微核的剂量效应关系[J]. 辐射研究与辐射工艺学报, 1991,9(3):182-185.

Bai Yushu, Zhang Xiuxia, Guan Shurong, et al. THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS[J]. Journal of Radiation Research and Radiation Processing, 1991,9(3):182-185.
白玉书, 张秀霞, 关树荣, 等. 用CB法研究分次照射时微核的剂量效应关系[J]. 辐射研究与辐射工艺学报, 1991,9(3):182-185. DOI：

Bai Yushu, Zhang Xiuxia, Guan Shurong, et al. THE USE OF CYTOKINESIS-BLOCK METHOD TO STUDY THE MICRONUCLEUS FREQUENCIES IN RABBITS EXPOSED TO FRACTIONATED WHOLEBODY ⁶⁰Co GAMMA-RAYS[J]. Journal of Radiation Research and Radiation Processing, 1991,9(3):182-185. DOI：

摘要

每日给家兔一次全身照射1 Gy ,60,Co γ线，共4日，总剂量4 Gy。照前和每次照射后检查微核。在分次和一次照射后，微核率随剂量增加而增加，大部分相应剂量点一次照射高于分次照射。当4 Gy时，二者差异有非常显著性（P,<,0.01）。曲线拟合表明，一次照射的微核率适于二次多项式（,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649881&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649885&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649897&type=,），分次照射的微核率适于纯二次式（,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649900&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649902&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649901&type=,）。

Abstract

The changes in the frequencies of micronuclei in CB cells were observed after irradiations of rabbits exposed to single or fractionated wholebody ,60,Co γ-rays. The frequencies of micronuclei showed a increase with the doses. At the same doses micronucleus frequencies in wholebody irradiations were higher than those in fractionated irradiations. The differences between them were very significant at 4 Gy dose. Micronucleus frequencies in single irradiations gave the best to the second degree polynomial model (,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649903&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649905&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649904&type=,), but micronucleus frequencies in fractionated irradiations gave the best to the quadratic equation (,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649907&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649921&type=,http://html.publish.founderss.cn/rc-pub/api/common/picture?pictureId=42649920&type=,).

关键词

分次照射家兔微核胞质分裂阻断法松胞素-B

Keywords

Fractionated irradiationsRabbitMicronucleiCytokinesis-block methodCytochalasin-B

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