EFFECT OF <sup>60</sup>Co γ-IRRADIATION ON THE CELL SURFACE CHARGE AND <sup>32</sup>P-INCORPORATION RATE IN RABBIT AND RAT ERYTHROCYTES

Wang Ruqin; Wang Xiucheng; Li Jin; Zhang Baolin; Li Zhiwang

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EFFECT OF ⁶⁰Co γ-IRRADIATION ON THE CELL SURFACE CHARGE AND ³²P-INCORPORATION RATE IN RABBIT AND RAT ERYTHROCYTES

更新时间：2023-04-18

- EFFECT OF ⁶⁰Co γ-IRRADIATION ON THE CELL SURFACE CHARGE AND ³²P-INCORPORATION RATE IN RABBIT AND RAT ERYTHROCYTES
- Journal of Radiation Research and Radiation Processing Vol. 1, Issue 1, Pages: 69-73(1983)
- 作者机构：
  
  1.中国医学科学院放射医学研究所
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Wang Ruqin, Wang Xiucheng, Li Jin, et al. EFFECT OF ⁶⁰Co γ-IRRADIATION ON THE CELL SURFACE CHARGE AND ³²P-INCORPORATION RATE IN RABBIT AND RAT ERYTHROCYTES. [J]. Journal of Radiation Research and Radiation Processing 1(1):69-73(1983)
DOI：

Wang Ruqin, Wang Xiucheng, Li Jin, et al. EFFECT OF ⁶⁰Co γ-IRRADIATION ON THE CELL SURFACE CHARGE AND ³²P-INCORPORATION RATE IN RABBIT AND RAT ERYTHROCYTES. [J]. Journal of Radiation Research and Radiation Processing 1(1):69-73(1983) DOI：

摘要

离体的家兔和大鼠红细胞在37℃下经γ射线照射约250、1000、3000和5000rad后2及4小时，电泳泳动度(EPM）及,32,P掺入量均未见变化。而家兔经γ射线全身照射约600rad后2及4小时，可见红细胞EPM减慢，,32,P掺入量增高。照射后2及4小时的家兔血浆，可导致正常家兔红细胞EPM及,32,P掺入量相似的变化。该血浆经56℃灭活处理，仍不失其活性。家兔经约600rad照射后2及4小时，血浆cAMP含量增高，24小时后恢复。

Abstract

There were no changes of electrophoretic mobility (EPM) and ,32,P-incorporation rate in rabbit and rat erythrocytes 2 and 4 hrs after the irradiation of erythrocytes in vitro at 37℃ by γ-rays with doses of 250, 1000, 3000 and 5000 rad.,However, the cell EPM decreased and the ,32,P-incorporation rate increased markedly 2 and 4 hrs after the total irradiation of rabbits or rats with 600 rad.,The plasma taken from rabbits 2 and 4 hrs after irradiation could induce the similar changes in normal rabbit erythrocytes. Such activity of plasma from irradiated rabbit was preserved after inactivation by 56℃ for 15 min. cAMP level in rabbit plasma 2 and 4 hrs after irradiation increased and recovered to normal in 24 hrs.

关键词

辐射效应细胞膜细胞表面电荷红细胞电泳泳动度红细胞32P掺入量

Keywords

Radiation effectsCell membraneCell surface chargeElectrophoretic mobility (EPM)32P-incorporation rate

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EFFECT OF 60Co γ-IRRADIATION ON THE CELL SURFACE CHARGE AND 32P-INCORPORATION RATE IN RABBIT AND RAT ERYTHROCYTES

DOI：

摘要

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EFFECT OF ⁶⁰Co γ-IRRADIATION ON THE CELL SURFACE CHARGE AND ³²P-INCORPORATION RATE IN RABBIT AND RAT ERYTHROCYTES