AGE INFLUENCE ON RETENTION, DISTRIBUTION AND INTERNAL DOSES OF <sup>85</sup>Sr IN RAT

Tian Wuxun; Wang Deheng; Zhang Hongyuan; Wen Quanfa; Hu Yuexin; Zhao Shanyin; Wang Lanjing; Cai Ping; Li Yong; Liu Tongshui

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AGE INFLUENCE ON RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁸⁵Sr IN RAT

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- AGE INFLUENCE ON RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁸⁵Sr IN RAT
- Journal of Radiation Research and Radiation Processing Vol. 8, Issue 1, Pages: 22-27(1990)
- 作者机构：
  
  海军医学研究所，上海
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1990-02，
  
  Received：30 August 1988，
- 稿件说明：
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Tian Wuxun, Wang Deheng, Zhang Hongyuan, et al. AGE INFLUENCE ON RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁸⁵Sr IN RAT. [J]. Journal of Radiation Research and Radiation Processing, 1990,8(1):22-27.
DOI：

Tian Wuxun, Wang Deheng, Zhang Hongyuan, et al. AGE INFLUENCE ON RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁸⁵Sr IN RAT. [J]. Journal of Radiation Research and Radiation Processing, 1990,8(1):22-27. DOI：

摘要

Sr注入静脉后，大鼠全身Sr的滞留可拟合成二项指数方程，方程参数在幼年组与成年、老年组间有显著差异（P

0.01）

而成年与老年组之间差异不明显，慢库室的生物半排期Tb

从幼年至老年组依次减小。骨滞留方程中，幼年组的生物半排期明显小于成年组和老年组。估算的全身及红骨髓剂量，幼年组是成年组的4.2倍，是老年组的6.2和5.9倍。剂量累积速度以幼年组最快，成年和老年组大致相等。

Abstract

After I. V

the whole body

Sr-retentions in rats were fit to two compartment exponential equations. The equation parameters showed a sigificantly difference between the young group and both the adult and old groups (p

0.01)

but there is no significant difference seen between the latter two groups. The biological half life(Tb

) for

Sr in the slow compartment decreased in regular order from the young to the old groups. In the bone

Sr-retention equations Tb

of the slow compartment for

Sr in the young group was sigificantly lower than the adult and old groups. The doses of the whole body and red-marrow for young rats were 4.2 times as much as those of adult rats

d 6.2 and 5.9 times as much as those old rats. The dose-cumulative speeds was most quick in the young groups and similar in the adult and the old.

关键词

85Sr滞留分布内剂量年龄差异

Keywords

85SrRetention distributionInternal doseAge difference

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AGE INFLUENCE ON RETENTION, DISTRIBUTION AND INTERNAL DOSES OF 85Sr IN RAT

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AGE INFLUENCE ON RETENTION, DISTRIBUTION AND INTERNAL DOSES OF ⁸⁵Sr IN RAT