暂无标题

HE Huocong1; WU Junxin1; SU Yin1; PAN Jianru2; ZHENG Guangjin2; LIU Shutao2

doi:10.11889/j.1000-3436.2012.rrj.30.120212

您当前的位置：

首页 >

文章列表页 >

暂无标题

更新时间：2021-12-01

- 暂无标题
- Journal of Radiation Research and Radiation Processing Vol. 30, Issue 2, Pages: 125-128(2012)
- 作者机构：
  
  1. 1（福建医科大学教学医院福建省肿瘤医院）,福州,350014
  2. 2（福州大学生物工程研究所）,福州,350002
- 作者简介：
- 基金信息：
- DOI：10.11889/j.1000-3436.2012.rrj.30.120212
  CLC：
扫描看全文
HE Huocong1, WU Junxin1, SU Yin1, et al. [J]. Journal of Radiation Research and Radiation Processing 30(2):125-128(2012)
DOI：

HE Huocong1, WU Junxin1, SU Yin1, et al. [J]. Journal of Radiation Research and Radiation Processing 30(2):125-128(2012) DOI： 10.11889/j.1000-3436.2012.rrj.30.120212.

摘要

本研究用6 Gy X射线对小鼠进行全身一次性照射，分别在照射后1、3和7 d经颈椎脱臼处死，测定小鼠外周血红、白细胞数量，胸腺指数和脾脏指数，骨髓嗜多染红细胞微核形成率以及肝脏抗氧化水平。结果表明：照射24 h后，小鼠外周血白细胞数量急剧降低，胸腺指数和脾脏指数下降，骨髓嗜多染红细胞微核形成率增加，肝脏脂质过氧化水平上升。放射7 d后，胸腺指数稍有回升，骨髓红细胞微核形成率和肝脏脂质过氧化水平略为降低，其它指标随时间变化损伤程度持续增加。

Abstract

Mice were whole-body exposed to X-rays with absorbed dose of 6 Gy and sacrificed on the 1st, 3rd and 7th day by cervical dislocation after irradiation, respectively. The number of red blood cells and white blood cells in peripheral blood, the index of thymus and spleen, the micronucleus rate of bone marrow polychromatic erythroblasts (PCE) and the level of antioxidant of liver were determined. It was observed that white blood cells decreased, the index of thymus and spleen also decreased meanwhile both of the micronucleus rate of bone marrow PCE and level of lipid peroxidation of liver increased at 24 h after irradiation. However, the index of thymus was up slightly on the 7th day after irradiation, while the PCE and the level of lipid peroxidation of liver got down slightly. The other index of injured mice increased continually with time.Cited

关键词

X射线辐射损伤小鼠

Keywords

X-raysRadiation damageMouse

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Progress in the research on radiation-induced defects in nanomaterials

Protective effect of Lanzhou lily polysaccharide fragment on X-ray-induced injury of bone marrow nucleated cells in mice

Protective effects of Sipunculus nudus polysaccharide on radiation damage in human intestinal epithelial cells

Radioprotective effects of Angelica sinensis protein on mice

Comparison study on X-ray radiosensitivity in three tumor cell lines

Related Author

No data

Related Institution

College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics

Medical College of Northwest Minzu University, Laboratory of Environmental Ecology and Population Health in Northwest Minority Regions of Northwest Minzu University

Naval Medical Research Institute, The Second Military Medical University

College of Food Science & Technology, Shanghai Ocean University

Institute of Radiation Medicine, Fudan University

⁰

暂无标题

DOI：10.11889/j.1000-3436.2012.rrj.30.120212

摘要

Abstract

关键词

Keywords

references