最新刊期
      期 2 ， 1986
      • Huang Mingxin
        Vol. 4, Issue 2, Pages: 1-8(1986)
        摘要：66 papers about research work on radioprotectors published mainly in 1983—1984 are reviewed. They include sulfur-containing compounds, heterocyclic compounds, amines, antioxidants, hydroxyl compounds and sugars, sex hormones, antibiotics and vitamins, biological and biochemical preparations, products of microorganisms and immunomodulating drugs, plant preparations, metals and their complex, etc. Researches on mechanisms of protective effects of radioprotectors are reviewed also. Impressions can be derived from the survey that researches on radioprotectors have made much progress recently. It includes the understanding of mechanisms of the action of radioprotectors, application of radioprotectors to clinical practice, and the extensive investigation on new protective substances. However, new effective compounds and preparations primarily tested should be chosen and studied further to illustrate the possibility of applying them in clinical practice.  
        关键词：Radioprotector;Radioprotective agent   
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        发布时间：2023-04-26
      • Zheng Xiulong,Meng XiangShun,Gao Jianguo
        Vol. 4, Issue 2, Pages: 9-14(1986)
        摘要：Murine lymphoid leukemia L7712 cells were incubated with various concentrations of PSD-007, the inhibition of DNA synthesis was observed, the degree of inhibition was proportional to the concentration of the PSD-007 (below 10 µg/ml) in the cultural medium, the inhibition increased slowly above that level.There were no differences in the degree of DNA strand breaks between 10 Gy γ-ray irradiated cells versus PSD-007 treated cells irradiated at the same dose in dark. It showed PSD-007 was unable to induce the effect of ionizing radiation on DNA damage in dark. However, when the treated cells alone were irradiated by 10 Gy γ-ray in visible light, the degree of DNA strand breaks increased distinctly and gave a clear difference versus protected from light group respectively, whereas the treated cells alone exposed to visible light at same conditions, there could not be observed any DNA damage. These results showed that PSD-007 could sole enhance the DNA strand breaks of L7712 cells by γ ray irradiation under visible light. This new phenomenon denoted that PSD also may be used in cancer radiotherapy under some circumstances.The effects of PSD-007 and/or γ ray radiation on DNA and the influence of many factors on assay methods are discussed.  
        关键词：Photosensitizer;Inhibition of DNA synthesis;DNA strand breaks   
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        发布时间：2023-04-26
      • Zhang Zhonglun,Li Fengzhang,Lang Shuyu
        Vol. 4, Issue 2, Pages: 15-21(1986)
        摘要：The model BPS TE-TE spherical cavity ionization chambers have been constructed in Institute of Biophysics, Academia Sinica. The basic performences of the chambers have been measured. The results of measurement of the saturation characteristics show that the relation between Qs/Qv and V-2 is linear in 60Co photon field and between Is/Iv and V-1 is linear in D+T neutron photon mixed field. The correlation coefficients is extremely close to l. The saturation correction factors were obtained.The wall thickness correction factors for determination of free-in-air are (0.60 ±0.88) ×10-2mm-1 and (0.49±0.35) ×10-2mm-1 for 15 MeV neutrons and 60Co photons respectively. The relative change of the response with angle of irradiation is not larger than 0.5 per cent when incident degrees of the radiation is in the range of 0~120° for the 60Co gamma rays but is about one per cent for the 15 MeV neutrons. The influences of stem scatter and radiation sensitivity of stem were studied in photon and neutron fields for irradiation free-in-air. The ratios of readings with TE gas and air were measured for TE-gas and calculated with the ratios of CH4, CO2, N2 given by Williams. The values measured and calculated are coincident. The effect of TE gas flow rate on the readings of the chamber was observed.  
        关键词：Spherical ionization chamber;Measurement in neutron field;Correction factors;Neutron absorbed dose;Tissue equivalent ionization chamber   
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        发布时间：2023-04-26
      • Wei Genshuan,Wu Jilan,Pan Xianming
        Vol. 4, Issue 2, Pages: 22-27(1986)
        摘要：The nature and structure of strong complexing compounds or long chain acid phosphate formed in γ-irradiated TBP-dodecane system are studied by means of IR, MS and elements analysis. The mechanism of the formation of long chain acid phosphate and the inhibition by stilbene are investigated also. We found that stilbene is a very effective inhibitor for the radiolysis of TBP in the TBP-dodecane system.  
        关键词：Radiolysis;TBP;Dodecane;Inhibitor;Stilbene   
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        发布时间：2023-04-26
      • Che Jitai,Yan Meilan,Sun Jiazhen
        Vol. 4, Issue 2, Pages: 28-32(1986)
        摘要：Polymer bound palladium complex catalyst with grafting acrylonitrile on inorganic compound (MgO, Y-molecular sieve silica) by pre-radiation method were studied.The palladium- grafting polymers has been investigated by X-ray photoelectron spectroscopy (XPS) . It is indicated that peak width of C1S and O1S spectra of MgO-g-PAN-Pd (radiation-induced graft) is more than that of MgO-PAN-Pd (chemical graft) and peak numbers of former are one more than later.According to report in reference, this peak is attributed to group. Thus, the graft acrylonitrile on MgO may complete through oxygen atoms in MgO and β-carbon atoms in acrylonitrile. Polymer catalyst obtained by radiation grafting is a higher active hydrogenation catalyst for olefines and better antitoxic than that of one obtained by chemical method, and it has selectivity for hydrogenation catalyst.  
        关键词：Polymer catalyst;Palladium complex;Hydrogenation polyacrylonitrile;X-Ray photoelectron spectroscopy   
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        发布时间：2023-04-26
      • Chen Qu-e,He Jian,Su Ruizhen,Zhou Qiling,Dou Juanjuan
        Vol. 4, Issue 2, Pages: 33-36(1986)
        摘要：Human hepatocarcinoma cells, line 7703, suspended in PBS were incubated with hematoporphyrin (HP) at 37℃ for an hour and then irradiated by 340—370 nm UV for 32 minutes (~3.9×10-2 J/cm•2min) at 4℃.The Fornace and Kohn's method of alkaline elution combined with protease treatment was used for measuring the SSB and crosslink of cell DNA. Three results were obtained: (1) Cell DNA degradation occurred in incubating the cells with HP (3.1—50.0 µg/ml) for an hour. (2) The HP (50 µg/ml) photosensitization enhanced the cell DNA crosslinking by a factor of 2. (3) About 87% of the DNA in crosslinked substance induced by UV in the presence of HP is linked with protein. The enhancement of DNA crosslinking by HP photosensitization reported here has not been found in previous papers so the authors suggest that this phenomenon shoud not be overlooked in considering the mechanisms of cell killing in photoradiation therapy of cancer using HP as the photosensitizer.  
        关键词：Hematoporphyrin;Photosensitization;UV-irradiation;Hepatocarcinoma cell;DNA-protein crosslinking   
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        发布时间：2023-04-26
      • Zhu Bing chai,Zhang Hongyuan,Chen Gaichen,Han Guoxin,He Nanzhang,Jia Fuxing,Wang Congwu,Lü Jiaben,Wang Lanjin
        Vol. 4, Issue 2, Pages: 37-41(1986)
        摘要：Dogs were continualy exposed to 60Co r-rays at dose rates of 0.427 and 0.178 rad/day respectively for 3 years. The accumulated doses were 315.2 rad and 131.4 rad respectively. During the period of radiation and 3 years after, chromosome aberrations in peripheral blood lymphocytes have been observed. The results showed that the chromosome aberrations were mainly one hit-aberration, and the acentric fragmentt increased linearly with accumulated dose. According to the results, the acentric fragments can be used as a sensitive index for chronic radiation injury. Following three and six months after exposure the frequencies of acentric fragment decreased near to and within the control level respectively.  
        关键词：Low dose rate;Chromosome aberration;Acentric fragment;Dose-response curve   
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        发布时间：2023-04-26
      • Zhao Yongnian,Chen Xinfang,Zhang Lihua,Li Shuhua,Zhang Zicheng
        Vol. 4, Issue 2, Pages: 42-48(1986)
        摘要：The Raman spectra of gaseous products formed in radiation of two polymers, polydimethylsiloxane (PDMS) and polyethylene (PE) , have been studied in this paper. They are typical polymers which mainly crosslink during irradiation by 60Co gamma rays. At first, the Raman spectra of pure methane, ethane and hydrogen were detected in the 50 ml analogue tube (Fig. 1-b) , and three spectrum peaks at 2917 cm-1, 2954 cm-1 and 4157 cm-1 were obtained. Their intensities depending on contents of methane, ethane and hydrogen in the analogue tube are shown in Fig. 2. The results prove that intensity of Raman spectra of each gas is only related to its absolute content in the airtight vessel that has fixed volume and is not related to other gaseous contents in the same vessel. Then, two grams of PDMS are put in each of six 50 ml sample tube respectively (Fig. 1-b) and are radiated by various doses in vacuum. The Raman spectra of gaseous products formed in radiation of PDMS is shown in Fig. 3. After that, the intensities of Raman spectra at 2917 cm-1, 2954 cm-1 and 4157 cm-1 were compared with each corresponding standard curve in Fig. 2 and the amount of each component and total amount of gaseous products produced in irradiation of PDMS were estimated(see Tab. 1) . The radiation chemical yields (G Value) for gaseous products formed in radiolysis of PDMS at various doses can be calculated from equation (1) and are given in Tab. 2. The results indicate that the G values of total gaseous products and of each component are not changed with doses. The average values of G are G (total) =1,86; G(CH4) =1.05; G(C2H6) =0,23 and G(H2) =0,58. From the mechanism of dimolecular reaction, the results given in Tab. 2 and Fig. 4 were satisfactorily explained by using dynamic method. Finally, the radiation chemical yield of hydrogen produced in radiolysis of PE is also obtained, G(H2) =2.7.  
        关键词：Polydimethylsiloxane;Polyethylene;Raman spectrum;Radiation chemical yields of gaseous products;Radiation crosslinking;G-values   
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        发布时间：2023-04-26
      • Su Zongxian,Cao Jin,Wang Fujun,Sui Peng
        Vol. 4, Issue 2, Pages: 49-53(1986)
        摘要：The method for entrapment of Baker's yeast cell with invertase activity by 60Co radiation-induced polymerization of acrylaminde has been studied.Acrylaminde was used as a carrier and N, N'-methylene bisacrylamide as a cross-linking reagent. The influence of immobilized conditions (such as irradiation dose, polymerization temperature, amount of yeast and cross-linking reagent) on the enzymatic activity has been investigated. From the experiments it was found that the irradiation dose until 2×106rad has not a significant effect on the enzymatic activity. The immobilized cell which was prepared according to the optimum conditions was not only elastic but also hard and exhibited higher activity recovery. After the repeated use 10 tims of batch reaction the enzymatic activity didn't change.  
        关键词：Radiation-induced polymerization;Acrylamide;Invertase;Sucrose   
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        发布时间：2023-04-26
      • Zhou Zhixiong,Zhang Xingfa,Yang Pinliang
        Vol. 4, Issue 2, Pages: 54-58(1986)
        摘要：This paper presents the main results of research on storage of melon and fruit in Xinjiang from 1976 to 1981.In this period of time, we had inrestigated the storage of Seedless grapes, Hamimelons and kuerle-pears in Xinyiang with X-ray, β-ray and atmospheric negative ion which were produced by a 2 MeV electronic electrostatic acceleratoro These experimental results are shown as follows. The seedless-grapes were treated by the atomespheric negative ion have better storage effects. than those treated by both the X-ray or the β-rayThe Hami-melons were radiated with the low dose of β-ray evidently have longer storage period and bigger.The Kuerle-Pears were treated by the atmospheric negative ion. nine months later, 91.9% of the Kuerle-Pears were survived and no big change of skin, flavor, quality and form of the Kuerle-Pears were seen.  
        关键词：Storage of melon and fruit;Radiation;Atmospheric negative ion;Hami-melon;Kuerle-Pear;Seedless-grape   
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        发布时间：2023-04-26
      • Ren Chouyang
        Vol. 4, Issue 2, Pages: 59-62(1986)
        摘要：The article studied the top roller cover irradiated by 60Co γ-rays which possess good abrasion resistabce, decrease deformation and tangling and improve yare evenness.  
        关键词：Irradiation;Rubber rollers;Abrasion;Cleformation;Tangling lint;Yarn eveness   
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        发布时间：2023-04-26
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