最新刊期
      期 3 ， 2003
      • WANG Rui,LI Shuzhong
        Vol. 21, Issue 3, Pages: 161-168(2003)
        摘要：The article revealed fundamental rules of elementary polymers which can be used to produce radiation crosslinked heat shrinkable materials, such as LDPE, EVA, EEA, EPDM, and polymer blends like LDPE/EVA, LDPE/EPDM, and EVA/PDMVS, etc. Radiation crosslinking of blends of heterogeneous system with additives is discussed. Changes in basic structures and main properties of the polymeric materials after crosslinking, and recent progresses in studies on the radiation crosslinked polymers, are discussed, too Applications of radiation crosslinked heat shrinkable material, along with the future development, are summarized.  
        关键词：Polymer;Radiation crosslinking;Heat shrinkable material;Aggregative state structure;Physical property   
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        发布时间：2023-03-30
      • FU Haiying,YAO Side,WU Guozhong
        Vol. 21, Issue 3, Pages: 169-173(2003)
        摘要：Reaction rate constants of sodium alginate with both sulfate and carbonate anion radicals were determined by laser flash photolysis and pulse radiolysis, respectively. The relationship between molecular weight of the sodium alginate and absorbed dose was discussed. Degradations of the sodium alginate were caused by OH• radicals and other oxidative radicals, because the oxidation at the C-4 carbon resulted in the breakage of the glycosidic C1-O-C4 bond in the main chain of sodium alginate.  
        关键词：Sodium alginate;Pulse radiolysis;Laser photolysis;Radiation   
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        发布时间：2023-03-30
      • ZHANG Limin,LIU Shulin,CHEN Jianxin,TANG Fangdong
        Vol. 21, Issue 3, Pages: 174-178(2003)
        摘要：As a dosimetry lab participated in the project of IAEA / CRP on Development of Quality Assurance Program for SSDLs, we present in this paper experimental results and discussions on internal quality control trial, interlab dosimetry comparison, comparisons between experimental data of absorbed doses determined according to verification regulations in China and IAEA technical report series No.277, evaluation of calibration uncertainties, transfer of calibration quantity, and quality assurance manual for SSDL Shanghai.  
        关键词：Radiation dosimetry;SSDL;Quality assurance;Calibration   
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        发布时间：2023-03-30
      • WU Tieyi,MIAO Jinling,ZHAO Hongwei,DOU Daying,WANG Wenfeng,YAO Side,CHEN Zhilong
        Vol. 21, Issue 3, Pages: 179-183(2003)
        摘要：By use of time-resolved laser flash photolysis techniques, a preliminary study of the photochemical characters of pyrophaeophorbide-a derived from chlorophyll in silkworm excrement has been completed. It is found that these compounds have strong absorbance in all wavelength ranges under investigation, and produce excited triplet state with high quantum yields. Discussions were made on possible applications of the pyrophaeophorbide-a as photoactivated pesticide.  
        关键词：Pyrophaeophorbide-a;Photoactivated pesticide;Laser flash photolysis   
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        发布时间：2023-03-30
      • XIA Lanying,SUN Fang,HUANG Yuli,LÜ Yun
        Vol. 21, Issue 3, Pages: 184-188(2003)
        摘要：IR651 and IR1700 photoinitiators were used to compose UV−curing polyurathane adhesives by 30 seconds of exposion to UV lights. Shear strength of UV−curing adhesive containing IR1700 and IR651 were 8.3 and 0.6 MPa, respectively. Photosensitivity of the adhesives, obtained by the characteristic curves, were 2.85 and 4.03 mJ/cm2 for UV-curing adhesives containing IR1700 and IR651, respectively. It is concluded by the deep layer curing that IR1700 photoinitiators showed higher sensitivity than IR651.  
        关键词：UV-curing adhensive;Photoinitiator;Free radical;Photopolymerization   
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        发布时间：2023-03-30
      • WANG Huiyong,LIU Ruiqin,XIE Leidong,SHENG Kanglong,CHEN Yali,TANG Xin
        Vol. 21, Issue 3, Pages: 189-192(2003)
        摘要：A systematic study was done on radiation graft-copolymerization of wool samples irradiated by γ-rays with methanol solution of methacrylic acid glycidyl ester monomer. It was found that reaction atmosphere did not cause great effects to the graft-copolymerization reaction. The graft rate increased with increasing dose, reaching a status of equilibrium at 11kGy. With increasing monomer concentrations, the graft rate increased, too, whereas the graft efficiency decreased. Results of IR and SEM characterizations of the grafted samples showed that monomer had been grafted uniformly onto the wool fibers.  
        关键词：Wool;MAGE;Gamma ray radiation graft-copolymerization   
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        发布时间：2023-03-30
      • YANG Wei,LI Xiuyi,LI Xiujuan,TIAN Mei,GONG Shouliang
        Vol. 21, Issue 3, Pages: 193-197(2003)
        摘要：To investigate the optimal doses of X-ray irradiation and plasmid injection in the anti-tumor effect of the pEgr-IFN γ gene–radiotherapy in vivo, we observed the anti-tumor effect of the pEgr-IFN γ gene–radiotherapy with different doses of X-ray irradiation and plasmid injection in mice with B16 melanoma and detected the concentration of IFN γ in peripheral blood by ELISA. The results showed that the tumor growth rate of the mice irradiated locally with 20Gy X-rays after the plasmid injection was significantly lower (p<0.001) than that of the mice irradiated locally with 2Gy or 10Gy X-ray from the third day after irradiation and the mean survival period was longer (p<0.001). The results also showed that the tumor growth rate of the mice injected locally with 20μg or 30μg plasmid was significantly lower (p<0.05—0.001) than that of the mice injected locally with 10μg plasmid and the mean survival period was longer (p<0.01). It was found that the concentration of IFN γ in peripheral blood of the mice treated with gene-radiotherapy was higher than that of the mice of plasmid-treated group (p<0.05, p<0.05) or control group (p<0.01, p<0.05) on the first day and the third day after irradiation. These results suggested that the optimal dose of X-ray irradiation of the pEgr-IFN γ gene–radiotherapy in vivo was 20Gy and the optimal dose of plasmid injected into tumors was 20μg. By inducing the higher expression of IFN γ gene in the tumor, the pEgr-IFN γ gene–radiotherapy could increase the concentration of IFN γ in peripheral blood, so as to enhance the body’s immunologic function and anti-tumor ability.  
        关键词：pEgr-IFN γ reconstruction plasmid;Gene –radiotherapy;B16 melanoma;X-ray   
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        发布时间：2023-03-30
      • LIU Qingjie,YANG Yingjie,CHEN Jindi,CHEN Deqing
        Vol. 21, Issue 3, Pages: 198-201(2003)
        摘要：Male, Kunming mice were irradiated by different doses of 60Co γ −rays (0—3Gy) in either acute or chronic radiation, and the hair, teeth and femora samples were studied with ESR spectrometer. While no characteristic ESR signals were found with the hair and teeth samples, ESR spectra of the femora were characterized by enhanced signal intensities with increasing dose of both acute and chronic exposures to the radiation. Storage condition of the irradiated femora samples was studied. No significant changes in the ESR signal intensities were observed with the samples kept dry at room temperatures for up to 453 days, whereas the intensity decreased significantly (p<0.001) from the samples kept in formalin for just 7 days.  
        关键词：Mouse femur;Hair and teeth;Whole-body irradiation;ESR signal intensity;Storage condition   
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        发布时间：2023-03-30
      • ZHANG Xuan,GONG Shouliang,ZHANG Ming,LIU Shuzheng
        Vol. 21, Issue 3, Pages: 202-205(2003)
        摘要：The work is to explore the effects, and the mechanism, of melatonin (MLT) on the damage of immune functions in mice induced by ionizing radiation. MLT was given to C57BL / 6J Kunming mice through intraperitoneal injection 1h before whole-body irradiation with 2Gy X-rays. Twenty four hours after irradiation, the number of thymocytes and splenocytes, 3H-TdR incorporation rate (HTIR) of thymocytes and T and B lymphocyte transforming rates (TLTR and BLTR) induced by Con A and LPS were observed. The number of thymocytes and splenocytes, HTIR, TLTR and BLTR of the irradiated mice were lower significantly than those of the sham-irradiation group (p<0.001). For all groups injected with 0.5—10mg•kg-1 of MLT, the numbers of thymocytes and splenocytes were significantly higher than that in 0mg group (simple irradiation), with the 0.5mg•kg-1 MLT group being the highest. HTIR of thymocytes also increased significantly (p<0.01 or p<0.001), with the 0.5mg•kg-1 MLT group being the highest TLTR induced by Con A in the 0.5mg•kg-1 MLT group increased most significantly, while BLTR in 10mg•kg-1 MLT group increased most significantly. In addition, 2.5mg•kg-1 of MLT enhanced splenocyte LTR without the stimulation of the mitogens. It is concluded that MLT can reduce the damage to lymphocytes of the irradiated mice and has the protective effect on immune functions.  
        关键词：Melatonin (MLT);Ionizing radiation;Thymocyte;Splenocyte   
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        发布时间：2023-03-30
      • LIANG Xiaofeng,HU Tianxi,ZHAO Yaping,YU Wenli
        Vol. 21, Issue 3, Pages: 206-209(2003)
        摘要：Using 3-morpholino-sydnonimine (SIN-1) as peroxynitriate anion(ONOO-) generator and luminol as enhancer, a chemiluminescent (CL) system for screening ONOO- was established. Effects of pH, temperature and SIN-1 concentration on CL intensity were studied and the scavenging effects of trolox, tea polyphenol and quercetin on ONOO- were determined. Typical parameters of the CL system for determination ONOO- are SIN-1=0.30 mg/mL, luminal=1×10-4mol/L, pH7.4, and T=30℃. ONOO- scavenging abilities of quercetin, tea polyphenol and trolox were investigated with the CL system, with quercetin being the highest in the ability, whereas trolox being the lowest. The CL technique for determination of the formation and screening of ONOO- is quick, convenient, sensitive and steady.  
        关键词：SIN-1;ONOO-;Antioxidants   
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        发布时间：2023-03-30
      • ZHU Feipeng,WANG Hongfu,GAO Linfeng,JIN Weifang
        Vol. 21, Issue 3, Pages: 210-213(2003)
        摘要：The work is to study the effects of alpha-calciferol on bone mineral density, histomorphometry and biomechanics in rats with osteoporosis induced by irradiation of the rat kidney. 32 male SDrats of six months in age were randomly divided into 4 groups ( 8 rats per group), i.e. the model group,the sham group, the bone one group and the fosamax group. Osteoporosis was developed in the rats by irradiating the kidney. Then the rats were administrated orally as follows in a 90 days, 0.1g•kg-1 BW.d of alpha-calciferol for the bone one group, 10 mg•kg-1 BW.d of alendronate sodium in 1mL CMC for the fosamax group, and 1mL CMC for both the model group and sham group. BMD of L1-4, bone gistomorphometry and the bone biomechanical properties were measured. Compared with the model group, both the bone one group and the fosamax group were characterized with sigmificantly higher BMD of L1-4 (p<0.01), significantly larger volume and width of bone trabecula, smaller space of bone trabecula (p<0.05, p<0.01), and significantly larger maximal stress of femur and lumbar vertebra (p<0.05, p<0.01). It is concluded that Alphacalciferol can improve BMD, bone histomorphometry and bone biomechanical properties in rat osteoporosis induced by kidney irradiation.  
        关键词：Radiation;Kidney;Bone metabolism;Alpha-calciferol   
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        发布时间：2023-03-30
      • AI Guoping,SU Yongping,WEI Yongjiang,LIU Xiaohong,RAN Xinze,CHEN Tianmin
        Vol. 21, Issue 3, Pages: 214-217(2003)
        摘要：Light microscopy ,immunohistochemistry, ELISA and RT-PCR were used to explore the mechanism and regulated methods of small intestine mucosal immunity dysfunction in mice after 8Gy irradiation of 60Co γ-rays. Results show that the irradiation could directly injure intestine lymphocytes and inhibit the IL-4 mRNA expression of mesenteric lymphocytes, with the numbers of IgA secreting plasma cells and the quantity of mucous sIgA in the intestine being significantly reduced. It has been found that rhIL-4 could increase the number of IgA-secreting plasma cells in the lamina propria and quantity of mucous sIgA. This suggests that rhIL-4 could be of help for recovery of the function of intestinal mucosal immunity.  
        关键词：Irradiation;Intestine mucosal immunity;Secretory-IgA (sIgA);Interleukin-4   
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        发布时间：2023-03-30
      • LÜ Duicai,SU Liaoyuan
        Vol. 21, Issue 3, Pages: 218-221(2003)
        摘要：To find effect of lysate of spleen cells after LDR on NK activity of CD57 cells or non-CD57 cells. Lysate of spleen cells after LDR were extracted. McAb (anti CD57 cells) was used to separate CD57 cells from human peripheral blood by Panning direct method. The CD57 cells and non-CD57 cells were used as effective cells.K562 cells labeled by 3H-TdR were used as target cells. The ratio of effect cells to target cells was 10:1.NK activity of CD57 cells or non-CD57 cells with the lysate of spleen cells after LDR was reflected by the efficiency of anti tumor cells. The 3H-TdR incorporation in K562 cells cultured with non-CD57 cells was significantly lower than that with CD57 cells. After use of the lysate of spleen cells after LDR, NK activities of NK cells and non-NK cells were 1.24 and 1.58 respectively. They were both increased obviously compared with control groups. The effect of anti K562 cells of non-NK cells is even greater than that of NK cells. The lysate of spleen cells after LDR can enhance the effect of both non-NK cells and NK cells.  
        关键词：Low dose radiation (LDR);Lysate of spleen cells;Lymphocyte;NK activity   
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        发布时间：2023-03-30
      • ZHOU Juying,TU Yu,YU Zhiying,SU Liaoyuan,XU Changshao
        Vol. 21, Issue 3, Pages: 222-224(2003)
        摘要：The effects of hyperthermia and radiation on human glioma SHG−44 cells and the alteration of Fas/FasL expression in the treated cells were investigated. The sensitivity of SHG−44 cells to hyperthermia and radiation was measured by colony forming assay and flow cytometry (FCM). The expression of Fas/FasL was detected by RT−PCR. By hyperthermia ( 42°C, 40min) combined irradiation, the colony forming ratio was reduced in a more effective way than by just the irradiation. The TER was 1.95. The apoptosis ratios were 20.2, 29.3, 59.1%, respectively, for the control group , the just-irradiation group and the hyperthermia combined radiation group. The expression of Fas was found in the three groups, but the expression of FasL could be found only in the two treatment groups. Hyperthermia could boost the effectiveness of radiation against glioma cells significantly. This also indicates some relationships between apoptosis and Fas/FasL.  
        关键词：Human Glioma Cells;Radiation;Hyperthermia;Fas/FasL   
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        发布时间：2023-03-30
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