最新刊期
      期 4 ， 1987
      • Chen yuan,Zhou Mei,Kong Hua,Qi Fengju
        Vol. 5, Issue 4, Pages: 1-5(1987)
        摘要：In the present paper it was studied that the effect of irradiation in vitro of RBC on SeGSHPx activity to explore the cause of the decrease in SeGSHPx activity of RBC irradiated in vivo, the features of the changes in SeGSHPx activity of RBC irradiated in vitro and the role of enzyme in protection against radiation induced lipoperoxidation, The experimental results were: All RBC SeGSHPx activities were not decreased whether RBC was irradiated in normal saline solution or in plasma. The enzyme activities became higher as the incubation (4 hours) elapsed on the contrary. The regularity of the change was basically consistent with that in K+ loss and hemolysis of RBC irradiated in vitro. VE didn't show protection of RBC irradiated in vitro from lipoperoxidation, when RBC whose SeGSHPx was inhibited by iodoacetic acid was irradiated in vitro, VE showed protection of SeGSHPx irradiated in vitro and inhibited RBC from lipoperoxidation.  
        关键词：Radiation effect;Irradiation in vitro;RBC;Selenium-dependent glutathione peroxidase;Lipoperoxidation   
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        发布时间：2023-04-26
      • Wang Shicai,Xu Yongping,Zhu Xanglin,Liu Kejing,Chu Youdong
        Vol. 5, Issue 4, Pages: 6-9(1987)
        摘要：This paper repot the radiation-induced heat -shrinkable casing and membrane of polyethylene, including the describtion of their principle, apparatus, operation method, technology conditions and practical applications. Because the casings of fixed diamensions taken are separated from the sealed pipes, they can not cut off gas, and the casing diameters are uniform. Particularly, this apparatus can be applied to blow-expand the pipe larger than 10 mm diameter. Another characteristic is that the large side feeding reel may be installed outside the feeding box.  
        关键词：Radiation-crosslinking of polyethylene;Heat-shrinkable polymer   
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        发布时间：2023-04-26
      • Che Jitai,Yan Meilan,Sun Jiazhen,Chen Chuanzheng,Sun Ying
        Vol. 5, Issue 4, Pages: 10-13(1987)
        摘要：In this paper, the structure of the radiation graft copolymer of EVA-acrylic acid has been studied by infrared spectroscopy, electronic microscope and X-photo-electron spectroscopy, and the hydrophilicity of the copolymer has also been studied. The experiment results show that the surface structure of EVA varies apparently after acrylic acid is grafted on it, and that the hydrophilicty of EVA increases with the increase of graft rate.  
        关键词：60Co-radiation graft copolymerization;The graft copolymer of EVA-acrylic acid;Electronic microscope;XPS;Hydrophilicity   
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        发布时间：2023-04-26
      • Meng Ziqiang
        Vol. 5, Issue 4, Pages: 14-18(1987)
        摘要：The 60Co γ-ray induced single strand breaks of DNA and their rejoining in cultured chinese hamster lung (CHL) cells and mouse spleen cells isolated freshly from mice were detected by hydroxylapatite chromatography. The method is based on the observation that the rate of denaturation of DNA to single strands in alkali is increased after irradiation, the interpretation being that this effect is due to DNA strand breaks. The percentage of labeled DNA that remained double strand after 30 min alkali treatment was inversely proportional to the radiation dose within the range of 1-10Gy for the two kinds of cells.The DNA strand breaks in unirradiated spleen cells was more than in unirradiated CHL cells, but the yield of breaks induced per 0.01Gy was found to be similar in the spleen cells and CHL cells. In contrast with these findings, most DNA strand breaks in the CHL cells were rejoined within 30min, the breaks were rejoined faster in the cells incubated in medium with 20% new born calf serum after irradiation than in medium without any serum. The repair of damaged DNA could not be detected in the spleen cells cultured in RPMI 1640 medium without any serum.  
        关键词：Hydroxylapatite chromatography;DNA strand breaks;DNA repair;CHL cells;Mouse spleen cells   
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        发布时间：2023-04-26
      • Cao Enhua,Fan Xianjun
        Vol. 5, Issue 4, Pages: 19-23(1987)
        摘要：In this paper, the photodynamic effects df hematoporphyrin, Y-Hpd (which is prepared by Yangzhou Biochemical Pharmaceutical Co.) and photofrin-Ⅱ on S 180 tumour cells and HeLa cells were compared, with each other the concentration of three porphyrins in S 180 tumour cells or liposome were assayed after cellular uptake. In vitro the photodynamic cell killing activity of Y-Hpd was signficantly higher than that of hematoporphyrin and photo-frin-Ⅱ, their biological activity order is as follows: Y-Hpd, photofrin-II, hematoporphyrin. Comparing with hematoporphyrin, photofrin-Ⅱ, the concentration of Y-Hpd was the highest in S 180 tumour cells or liposome. It is indicated the level of porphyrins in cells is one of the important factors for evaluating their biological activity.  
        关键词：Hematoporphyrin derivative;Photosensitizer;Photodynamic effect;Photosensitization;Liposome   
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        发布时间：2023-04-26
      • Zhao Benxi,Zhu Xiaohong,Murat,Han Zhewen
        Vol. 5, Issue 4, Pages: 24-28(1987)
        摘要：The copolymer of tributytin methacrylate and methylmethacrylate is a useful self-polishing antifouling paints materials. It was synthesized by radiation polymerization using 60Co γ ray at room temperature. It was carried out to study the copolymerization kinetics of the pair of monomers. The relationship between the reaction rate and the dose rate was found to be RP=KP•I0.53 and the reactivity ratios were measured to be lass than 1. The overall activition energy was 1.29×104J/mol. It was Supposed that the copolymerization was of radical machanism.  
        关键词：Radiation Copolymerization;Antifouling paints;polymerization kineties;Organotin polymer;Polymerization rate   
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        发布时间：2023-04-26
      • Zhao Kejian,Lu Dunzhu,Wan Hong,Zhu Zhaonan,Xu Shanmei
        Vol. 5, Issue 4, Pages: 29-35(1987)
        摘要：The radiation effects on respiration and ethylene production in apple and its radiation preservation were reported in this paper. It shows that, when irradiation was applied immediately after harvest, the respiratory rate and ethylene production increases with the increasing of irradiation dose. When irradiation was applied after 7-10 days of storage, the respiratory rate still rises with the dose, while there is a decrease in ethylene production with the increasing of dose. If the irradiation dose is less than 800 Gy the rise of respiratory rate of irradiated apple caused by the irradiation came back to the level of the control within 5 days, but ethylene production of irradiated apple keeps a lower level. According to the above results, dose of 300-500 Gy may be recommended for radiation preseration of apple.Ascorbic acid is unstable and is sensitive to radiation, but the radiation effects on ascorbic acid in apple is very small, because the saccharides and some organic acid in apple, especially malic acid are able to protect ascorbic acid in apple from radiation damage. From measuring the saccharides and acids in apple, it is obvious that there is no significant difference between irradiated and unirradiated apple.Long-life free radical in apple was not detected after irradiation. Scald of apple reduced from 60% to less than 15% after cold storage for 8 monthes. The taste results indicated, tasting them without knowing which is irradiated or not, that the irradiated apple is superior to controlled sample.  
        关键词：Radiation preservation;Respiratory rate;Ethylene production;Ascorbic acid;Radioprotection scald   
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        发布时间：2023-04-26
      • Huang Chengyan,Zhao Shixu
        Vol. 5, Issue 4, Pages: 36-41(1987)
        摘要：In this experiment, seedlings of rye, maize and wheat were exposed to gamma rays with the doses of 77.2 Gy, 144.75 Gy and 289.5 Gy and a dose rate of 1.42 Gy/min. Root tips were taken for electron microscopic studies. The results indicated: As the increase of exposures and elongation of time after exposure, the degree of vacuolation in the root tip cells were increased up to intense vacuolation. The endoplasmic reticulum swelled gradually. Band-like and reticular vacuoles were formed from swelled endoplasmic reticulum. Endoplasmic reticulum and golgi apparatus were responsible for the vacuolization of the cells. Nucleus changed there shapes irregularly and sometimes micronucleus or micronuclei could be observed. Mitocondria cristae decreased, even disappeared, the matrix turned to light and outer and inner membrane broke forming disabied structures. No obvious structure damages were found on the golgi apparatus and cell wall.  
        关键词：Gamma rays;Cells;Ultrastructure;Influence   
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        发布时间：2023-04-26
      • Sheng Minli,Yu Aiguo
        Vol. 5, Issue 4, Pages: 42-45(1987)
        摘要：Platelets represent small pieces of cytoplasma released from the periphery of megakaryocytes. Therefore, the cells have no nucleus and normal blood platelet fixed in glytaraldehyde in the presence of rutherium red to enhance contrast of the platelet coat (black). The large empty appearing spaces form part of the open canalicular system. The band of microtubles runs peripheral to the membrane-bound granules which appear heterogeneous in size and electron density. The platelet possesses glycogen particles as well as mitochondria and it is able to use either metabolic pathway glycolysis of oridative phosphorylation. The platelets from rat irradiated by γ-ray with 500 rad. appear to be a disorderly array of microtubules in longitudinal and across section. The canalicular system appears excessive and markedly dissended. There is neither granules nor mitochondria in irradiated platelets.  
        关键词：Platelet;Microtubule;Canalicular;Granules;Mitochondria Radiation   
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        发布时间：2023-04-26
      • Jiang GuoLiang,Liu TaiFu
        Vol. 5, Issue 4, Pages: 46-49,5(1987)
        摘要：It has been reported that Tetrandrine, a Chinese medical herb, could enhance the radiotherapy of primary lung carcinomas. The purpose of the study was to verify whether Tetrandrine is a potential radiosensitizer. The experimental results showed the drug was not able to increase effects of radiation on S-180 and Lewis tumors, with E/O less than 1.4 in all experiments. There was no evidence to prove that the immediate radioresponse of primary lung carcinomas to combination of radiotherapy and Tetrandrine was better than that of radiotherapy alone. Therefore, probably Tetrandrine is not a radiosensitizer.  
        关键词：Radiosensitizer;Tetrandrine;Sarcoma-180;Lewis carcinoma   
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        发布时间：2023-04-26
      • Zhong Xiaoguang,Zhu Yufen,Li Xinmin,Sun Jiazhen
        Vol. 5, Issue 4, Pages: 50-53(1987)
        摘要：Radiation induced crosslinked polysulfone was studied by means of Pyrolysis Gas Chromatography (PGC). We suggested the possible crosslinking sites of polysulfone according to the change of the relative content of pyrolytic products with the radiation dose. The gelation doses of the polysulfone crosslinked at different temperature were obtained from the relationship of peak height ratio of benzene: toluene in pyrolytic spectra to radiation dose which were quite consistent with the value obtained from other method.  
        关键词：Radiation induced crosslinkihg;Pyrolysis Gas Chromatography;Polysulfone;Dose of gelation   
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        发布时间：2023-04-26
      • Gin Tao,Zhou Guanfwen,Zhang Minjian
        Vol. 5, Issue 4, Pages: 54-56,28(1987)
        摘要：This paper mainly reports the extrapolation chamber for electron or Beta ray dosimetry with removable electrodes. It is equivalent to air, tissue and silicon. The diameters of the collecting electrode are 1.5 mm, 3 mm, 10 mm and 30 mm respectively. Convertible range is 0.2 mm-15 mm. It has the characteristics of measuring the internal temperature in ionization cavity, changing automatically the thickness of equivalent material layers above the chamber window and being controled by a microcomputer etc. It may be applied to measure the electron of no more than 10 MeV energy with a range of 105-10-3 Gy/h absorbed dose rate. The uncertainty of the whole system is 2.3% in measuring the surface dose rate of the 204Tl isotope Beta ray source. It is about 3.0% in measuring the depth absorbed dose rate of silicon and "Hami" melons for electron.  
        关键词：Extrapolation chamber;Electron dose;Beta dose;Temperature in ionization cavity   
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        发布时间：2023-04-26
      • Wang Shun Bao,Wang Jheng,Shen Yu,Gu Xian Zhi
        Vol. 5, Issue 4, Pages: 57-59(1987)
        摘要：The transplantable spontaneous tumors MA 737 of JB2female mice were used, using take the tumor regrowth deley as the endpoint. The mice were injected HPD i.p. THe doses of HPD were 2-3 mg/kg, 20—30 mg/kg, 100—150 mg/kg respectively.Irradiations of 8 Mev β-ray generated from a linear accelerator were performed 4-8 hours after a single i. p. injection of HPD. The doses for irradiation were 5, 7, 12, 15, 20 Gy respectively. The results were analysed using a set of computer program.After the administration of 2-3 mg/kg of HPD, the sensitizing enhancement ratio was 1.2, Middle dose of 20-30 mg/kg, no higher effect was found. While the large dose of 100—150 mg/kg was used, the effect was even lower.  
        关键词：Radiosensitization;Hematoporphyrin derivative;Photosensitizing agents   
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        发布时间：2023-04-26
      • Xu Yindong,Su Liaoyuan
        Vol. 5, Issue 4, Pages: 60-61(1987)
        摘要：When the monoclonal antibodies (McAb) were created in the world, it turned a new page of the modern immunology. In the production and the application the McAb is becoming more and more widespread and profound. Some authors at home have used mitogenes to study the radiosensitivity of lymphocyte subsets, but using the monoclonal antibodies as a tool to study the radiation effect of lymphocyte subsets has not been reported in our country. Some authors in foreign countries have preliminarily done this kind of work.Three kinds of monoclonal antibodies were used in experiments; OKT4 McAb, OKT8 McAb and HI43 McAb to identify T helper (Th) , T suppresser (Ts) and B lymphocytes respectively. After lymphocytes were exposed to 0.1 Gy, 0.25 Gy, 1 Gy and 4 Gy 60Co γ-rays immediately, we observed the radiation effect by means of the immunofluorescence tests. 200 cells were counted to obtain the percent of immunofluorescence positive cells. The results indicated that when the Th, Ts and B lymphocytes were irradiated by 0.1 Gy 60Co γ-rays, their abilities to combine with McAb decreased significantly. The radiation effect became more and more obvious with increasing radiation dosage. Three kinds of the immunofluorescence positive cells percents were analysed with weighted linear regression methods. The relational coefficients (r) of Th, Ts and B lymphocytes were 0.8131, 0.8832 and 0.9086. The significant tests of regression coefficient showed that the radiosensitivities of Ts and B lymphocytes were higher than the Th lymphocytes. The Ts and B lymphocytes had no significant difference.Lymphocytes are the most radiosensitive cells in an organism. Its membrane is the radiation injury target of cells. There was a report said that when the lymphocytes were exposed to 0.25 Gy radiation, the ultrastructure variation of the cell membrane could be found.Our experiment showed that when the lymphocyte were exposed to 0.1 Gy 60Co γ-rays, the abilities of Th, Ts and B lymphocyte to combine with McAb decreased significantly although the cell's membrane had not been broken.  
          
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        发布时间：2023-04-26
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