最新刊期
      期 1 ， 1988
      • Tang Beilin,Tong Tianzhen
        Vol. 6, Issue 1, Pages: 1-5(1988)
        摘要：The researches for γ-irradiation effects on the drugs including alkaloids, glycosides, carbohydrates, sulphonamides, antibiotics, vitamins, enzymes, etc. in the field of sterilization over the past 20 years have been reviewed. Some regular patterns in this field have been summarized as well.  
        关键词：Radiation sterilization;Drug;Radiation stability   
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        发布时间：2023-04-23
      • Zhu Shoupeng,Zheng Siying,Wang Chongdao,Cao Genfa,Sun Baofu
        Vol. 6, Issue 1, Pages: 6-10(1988)
        摘要：Retention and transference of enriched uranium (UO2F2) were observed after iv once 20 mg/kg and ip 15 mg/kg qd× 3d to Wistar male rats. The dynamic retention of radioactivity in the body showed that enriched uranium (UO2F2) was chiefly localized in kidney, and then in skeletion and liver. The activity of enriched oranium(UO2F2) in skeleton rose steadily while the concentration in kidney and liver were droped. It was concluded that the retention peculiarity of enriched uranium was equal to the natural uranium.When enriched uranium(UO2F2)was accumulated in organism, it caused chromosome aberration on peripheral blood lymphocytes. Results indicated that the chromosome aberration rates were elevated when the dose of enriched uranium(UO2F2) was enlarged. At the same time the cell division was depressed.  
        关键词：Enriched uranium;UO2F2;retention;Chromosome aberration   
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        发布时间：2023-04-23
      • Wang Mingjun,Liu Yuming
        Vol. 6, Issue 1, Pages: 11-16(1988)
        摘要：From the kinetic equation of gel formation obtained by this study, the mechanism of gel formation may be interpreted clearly as follows:(1) When the degree of crosslinking q<qg, the system is sol and the crosslinking reaction is only carried out between the sol molecules. (qg is the gel point).(2) when q=qg, there exists a beginning point where the gel is coexisted with the sol, and the system is still sol, and the crosslinking reaction is still carried out between the sol molecules.(3) When q>qg, the crosslinking reaction exceeds the gel point and the gel is coexisted with the sol. The kinetic equation shows clearly that the transformation from sol into gel is caused by crosslinking reaction of the uncrosslinked chain units between the sol and gel molecules. As a result the sol molecules are transformed into the gel molecules gradually, and the sol fraction is reduced. When the chain units in sol are crosslinked with gel, the sol fraction in the system are reduced ds (where is a function of the radiation dose and S is sol fraction.)The degree of crasslinking per unit dose (q0) is reduced function of dose (R), so its value for every irradiation dose may be calculated by following equationtherefore, the relationship between q0 and R will be known. After knowing the correlation between vs R and q0 vs R, the distribution of gel and sol in the process of radiation crosslinking can be discussed according to the equation dR as well.  
        关键词：Sol fraction;Gel fraction;Gel point;Degree of crosslinking;Degree of degradation;kinetics of gel formation;Assignment of sol and gel   
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        发布时间：2023-04-23
      • Zhou Yiqin,Wu Hanqing,Chang Jixiang
        Vol. 6, Issue 1, Pages: 17-20(1988)
        摘要：The Thermally Stimulated Current (TSC) spectra of biaxial stretched polyethylene terephthalate (PET) electret were measue measured, which a had been irradiation by γ rays at dose rate 1×104Gy/h. The space charge peak's value and peak temperature are dramatically decreased with doses below 1×103Gy and then tend to a certain value respectively. The mechanism of decreasing the trap depth has been investigated by means of the comparing with TSC spectra of amorphous PET electret. It has been confirmed that the main species of charge carriers of amorphous PET are the holes.  
        关键词：Thermally Stimulated Current Electret;Trapping;Space charge;Species of charge carriers;Initial density of charge carriers   
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        发布时间：2023-04-23
      • Chen Jiapei,Liu Xiuying
        Vol. 6, Issue 1, Pages: 21-23,10(1988)
        摘要：The functional condition of bone marrow vessels was investigated by estimating the content of Evan's Blue, the plasma volume and the total blood volume in the bone marrow of the mice iv injected with Evan's Blue.The results showed that 6 hr later after 10 Gy total body irradiation the injuries of bone marrow vessels could be observed. It reached the peak at the 3 rd day post-irradiation. on the 10th day post-exposure, the functional condition of bone marrow vessels remained abnormal. At early stage after a local X-irradiation, the damagcs of bone marrow vessels occured. They were similar to that after total body irradiation. At the late stage, the content of dye, the plasma volume and the total blood volume were below the control level. The significance of this finding in hemopoletic failure after irradiation was discussed.  
        关键词：Irradiation;functional change of vessels   
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        发布时间：2023-04-23
      • Li Shuzhong,He Zhongda,Zhang Zicheng
        Vol. 6, Issue 1, Pages: 24-27,20(1988)
        摘要：The molecular motion and structure transitions of γ-irradiated trioxane and its polymer have been studied by the dielectric measurement. It was found that there was a change of microstructure (crystal lattice defect) in trioxane between 45℃ and 55℃. Release from defect and recombination of active species (R+) produced by radiation took place with rise of the temperature of the system. Since the polarity and the molecule motion lessened after postpolymerization of irradiated trioxane, the dielectric loss tangent (tgδ) was decreased. The transition from trioxane to polyoxymethylene has been observed from the dielectric spectra. The structure change of polyoxymethylene resulted from radiation degradation has been discussed by means of the dielectric spectrum.  
        关键词：Trioxane;Polyoxymethylene;Irradiation;Postpolymerization;Dielectric loss tangent;Temperature;Frequency;Structure transition;Molecular motion   
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        发布时间：2023-04-23
      • Bai Yushu,Zhang Xiuxia,Guan Shurong,Li Weijun,Xie Feng,Lu Meiying
        Vol. 6, Issue 1, Pages: 28-32(1988)
        摘要：An 241Am-Be neutron source of 120 millicrocurie was stolen by a boy on April the 3rd, 1982. He brought it to his home. The neutron source was broken and the radioactive substance contaminated the whole family. He and his other family members did not leave the contaminated environment for 70 days. There were altogether 14 persons exposed to the radioactive substances.Chromosome aberrations of peripheral blood lymphocytes of six exposed cases were analysed on an early day of June 1982. The exposure doses were estimated by the frequency of chromosome aberration. Biological dose absorbed by the boy who stole the source was about 96~128 mGy. (physical dose abous 120 mGy), the others were about 10~30 mGy (physical dose about 10~30 mGy). The results indicated that biological doses were quite approximate to the physical doses.One and half years after the accident, the analysis of stable chromosome aberrations for 14 exposed persons showed that the frequencies of chromosome aberrations of the irradiated individuals still were higher than those of the controls. The differences between them are very significant.  
        关键词：241Am-Be neutron source;Biological dose;Analysis of stable chromosome aberration;Micronucleus   
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        发布时间：2023-04-23
      • Yin Jianlin,Su Liaoyuan,Liu Keliand
        Vol. 6, Issue 1, Pages: 33-37(1988)
        摘要：The synthesis of DNA in T, B lymphocytes was investigated by the determination of 3H-TdR incorporation after Gamma-irradiation. The DNA ssb (single strand breaks) and repair in lymphocytes were measured by alkaline elution. The DNA synthesis in B lymphocytes was much lower than that in T lymphocytes. No significant difference in DNA ssb was found between T and B lymphocytes, but a less efficient process of repair was observed in B lymphocytes, So it was conceived that B lymphocytes were more sensitive to Gamma-irradiation than T lymphocytes and DNA synthesis might be related with the repair of DNA ssb.  
        关键词：DNA synthesis;DNA ssb;DNA repair;T lymphocytes;B lymphocytes;Radiosensitivity   
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        发布时间：2023-04-23
      • Ha Hongfei
        Vol. 6, Issue 1, Pages: 38-43(1988)
        摘要：Radiation-induced crosslinking and change of thermodynamic properties in polyethylene swollen in decalin and CCl4 at room temperature have been studied. There were marked decreases of crosslinking for the samples swollen in both solvent under irradiation in the absence of oxygen.It is known that the first melting temperature of PE irradiated in air decreased with increasing absorbed dose and above 0.6 MGy bimodel endotherms were obtained for high density PE in DSC thermograph. It was found in this work that for the HDPE samples swollen in decalin and CCl4 respectively after the same dose irradiation, the double peak disappeared. A possible mechanism was given.  
        关键词：Polyethylene;Radiation-induced crosslinking Swollen;DSC thermograph   
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        发布时间：2023-04-23
      • Liu Yuming,Yang Yueqi
        Vol. 6, Issue 1, Pages: 44-48(1988)
        摘要：This paper presents mainly the kinetic process of the radiation synthesis of PHEMA hydrogel The major results obtained are:(1) In the kinetic process, at first the HEMA is polymerized by radiation, and then the PHEMA gel is formed after conversion 20%.(2) The polymerization-crosslinking of HEMA is proceed by the free radical mechanism: Vo∝I0.6.(3) This radiation-crosslinking process only need a small irradiation dose such as less than 1×104Gy, thus a high gel (more than 90%)can be obtained.(4) The properties of PHEMA hydrogel are as follows:water absorption(%)*ηO2**ηCO2tensile strength(kg/cm2)elongation(%)20～7010-11～10-910-11～10-95～30100～300* permeability coefficient of O2 (ml•cm/cm2•s•cmHg)** permeability coefficient of CO2 (ml•cm/cm2•s•cmHg)  
        关键词：Hydrogel;Polymerization-crosslinking process;Gel;Sol..   
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        发布时间：2023-04-23
      • Cao Jin,Su Zongxian
        Vol. 6, Issue 1, Pages: 49-52(1988)
        摘要：The immobilized glucose oxidase (GOD) by 60Co-γ induced polymerization of HEMA at -78℃ was studied. From the experiment results, it was found that the irradation dose until 1×104Gy had not a significant effect on the native GOD activity. When the carrier (HEMA) concentration was 50%, entrapped amount 1.0 ml GOD/10 ml phosphoric acid buffer solution, the immobilized GOD had not only elastic, but also had high remaining activity. The native GOD was less sensitive fo pH value than the immobilized GOD, but both the proper pH values didn't change.The kinetic reaction results showed, Michaelis constant k'm=1.42×10-2mol (native GOD km=1.0×10-2mol). This value indicated that diffuse velocity of substitue was restricted. The activation energies of the immobilized GOD were found to be 13.7 kJ/mol.  
        关键词：Immobilized enzyme;Entrapped immobilized method;Glucose oxidase;Radiation-induced polymerization;Glucose;β-Hydroxyethyl Methacrylate(HEMA)   
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        发布时间：2023-04-23
      • Luo Zuyu
        Vol. 6, Issue 1, Pages: 53-57(1988)
        摘要：The 2 nd conference on anticarcinogenesis and radiation protection was introduced in this paper. It consists of five parts. The contents focus on oxidative stress and molecular damage caused by radiation and chemical pro-oxidative and this role in carcinogenesis; and on mechanisms of deregulalation of the expression of oncogenes and some other genes in carcinogenic initiation and promotion.  
        关键词：Free radical scavenger;Chemical modifiers;Carcinogenesis and anticarcinogenesis;Lipid peroxidation and antioxidants;Antipromotion   
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        发布时间：2023-04-23
      • Zhong Xiaoguang,Zhang Wanxi,Zhang Yunfang,Sun Jiazhen,Chen Chuanzheng,Sun Ying
        Vol. 6, Issue 1, Pages: 58-60,F4(1988)
        摘要：Radiation induced crosslinked polysulfone was studied by means of X-rays photoelectron Spectroscopy(XPS). It was found that the relative intensity of the shake up peak of polysulfone irradiated at lower temperature decreased with the increase of dose, while that of polysulfone irradiated at higher temperature increased. with it. This showed the different crosslinking bond formed in polysulfone irradiated at different temperature. By XPS method we obtained the gelation dose of polysulone which was quite consistent with the value obtained from other method.  
        关键词：XPS. Shake up peak;The crosslinking of polysulfong;Dose of gelation   
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        发布时间：2023-04-23
      • Tan Fusheng,Xin Luyong,Zhou Hongyan
        Vol. 6, Issue 1, Pages: 61-64,37(1988)
        摘要：We carried out irradiation of kanamycin strain with fast neutron and high energy electron for many times. Our practice proved, when the selected mutagenic doses were suitable, for example, 0.10~0.20 kGy for high energy electron and 1~8×1012 No. of neutron/cm2 for fast neutron, there were more high mutagenic effects. Besides the suitable mutagenic dosess, the mutagenic effects were in connection with strain sensitivity, irradiation method, selection condition etc. By electron irradiation mutagenic treatment of kanamycin strain, a new kind strain was obtained. Its potency of shak bottle has been increased 10.34~30.8% and the production yield has been increased 4.07~5.23%.  
        关键词：Kamaycin;Irradiation;Mutagenisis   
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        发布时间：2023-04-23
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