最新刊期
      期 4 ， 1999
      • CHEN Jie,NHO Youngchang
        Vol. 17, Issue 4, Pages: 193-198(1999)
        摘要：The surface of polypropylene (PP) film is modified by preirradiation grafting of polyethylene glycol methacrylate (PEGMA) with three kind of different molecular weight. The effect of co-solvent system on the degree of grafting and water contact angle were determined, respectively. The Fourier Transform Infrared (FTIR) spectroscopy in the attenuated total reflectance mode (ATR) was used for the determination of grafted surface. The blood compatibility. Such as protein adsorption, platelet adsorption and thrombus on the grafted surfaces were modi fied respectively.  
        关键词：Radiation grafting;Polypropylene;PEGMA;γ-rays;Blood compatibility   
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        发布时间：2023-04-07
      • PENG Ruiyun,WANG Dewen,XIONG Chengqi,GAO Yabing,WANG Baozhen,LI Yanping,YANG Hong,CUI Yufang
        Vol. 17, Issue 4, Pages: 199-203(1999)
        摘要：213 LACA mice were irradiated respectively with dose of 2.5,4.0, 5.5 and 7.0 Gy γ-rays and sacrificed within 4 weeks after radiation. By means of light and electron microscopy, in situ terminal labeling and biochemical analysis apoptotic hematopoietic cells apoptosis were investigated in irradiated mouse bone marrow. The results showed: Much more apoptotic cells were found in each irradiated group bone marrow at 6 h after radiation. Furthermore, the higher radiation dose was, the more apoptotic cells were. The characteristics of apoptotic cells were the chromatin condensation and margination, just as half-moon,ring-like or irregular shapes. The nucleus may be break up and became apoptotic bodies. There was DNA degradation of apoptotic cells detected by in situ terminal labeling and DNA ladder formation in agarose gel electrophoresis. Conclusion: At the range of 2.5 to 7.0Gy irradiation,apoptosis is the main pathway for radiation-induced hematopoietic cells death.  
        关键词：Bone marrow;Radiation;Apoptosis;In situ terminal labeling;DNA agarose gel etectrophoresis   
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        发布时间：2023-04-07
      • ZHANG Yuguang,ZHANG Xinru,YAN Yujung,YANG Yi,HAN Ying,LI Zhiwang
        Vol. 17, Issue 4, Pages: 204-208(1999)
        摘要：E838 is a better radioprotecter that is derivative of estrogen. E838 inhibits cell proliferation of MCF7 cell line in vitro, D0 is 3.9µg/mL,IC50 is 5.6µg/mL. It also inhibits the growth of tumor bearing mice that extend the living time and enhance the effect of radiotherapy. Up till now, E838 haven't been fond the effect of stimulate and promote tumor metastasis. E838 has the possibility as an auxiliary medicine using in radiotherapy of tumors.  
        关键词：E838;Cell proliferation;Metastatic carcinoma   
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        发布时间：2023-04-07
      • CHEN Honghong,HU Yuxing,ZHANG Yani,YANG Zhaohua,WANG Yihua,LUO Meichu,SUN Meizhen
        Vol. 17, Issue 4, Pages: 209-213(1999)
        摘要：Effects of single molecular and double molecular substituted phenolic chelating agents on scavenging of superoxide anions and hydroxyl radicals and inhibition of rat liver mitochondria lipid peroxidation induced by irradiation were studied. The phenolic chelating agents were shown to different extent to scavenge oxygen free radicals and to protect against radiation-induced lipid peroxidations, and their half inhibition concentrations (IC50) on hydroxyl radicals generation and lipid peroxidation were 1×10-6mol/L, which of scavenging of superoxide anions were 1×10-3mol/L. 7601 (CBMIDA) , 9501 and 9502 were the best among them. The free radical scavenging and antioxidant activities were close related to chemical structure and decorporated bioactivity.  
        关键词：Phenolic chelating agents;Superoxide anion radical;Hydroxyl radical;Radiation-induced lipid peroxidation   
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        发布时间：2023-04-07
      • YANG Zhanshan,ZHU Nankang,YANG Shuqin
        Vol. 17, Issue 4, Pages: 214-218(1999)
        摘要：Reinforced poly (ethylene oxide) blend hydrogel films containing mafenide acetate were prepared by using two freezing-thawing cycles and the irradiation crosslinking technique, and their properties and the drug release were assessed. The results showed that the tensile strength of the reinforced PEO blend hydrogel films increased significantly (p <0.01) ,the gel fraction and the elongation at break of the films increased slightly as compared with those formed by the irradiation without the freezing-thawing treatment, indicating that the mechanical properties of the PEO blend hydrogel films can be improved by the freezing-thawing cycles. The reinforced films possessed an ideal flexibility, crosslinking density and elasticity as wound dressings. Swelling studies showed that the equilibrium water content of the hydrogel films expressed in the degree of swelling decreased significantly (p <0.01) , suggesting that a significant structural rearrangement of the films occurred during the freezing process. The structural densification resulted in the increase of the mechanical strength of the hydrogel films. The hydrogels formed by the irradiation at doses of 40 kGy were comparatively stronger. Release studies were run on the reinforced hydrogels with mafenide acetate which was incorporated before the freezing-thawing treatment. Release was followed over seven days. The drug transport was controlled by a regular diffusion model.  
        关键词：Poly(ethylene oxide);Hydrogel;Freezing-thawing treatment;Irradiation crosslinking;Mafenide acetate;Drug release   
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        发布时间：2023-04-07
      • SONG Guangjie,WU Hui,JIN Yangzhi
        Vol. 17, Issue 4, Pages: 219-224(1999)
        摘要：Five different forms,four ratioes and three kinds of alkali developable photosensitive resins were systhesized. Especially this paper studied their alkali developable as well as the light curing speed. Along with adding the ratio between photosensitive resin and maleic anhydride,alkali developable was better and the light curing speed was faster. When the ratio was more than 1:0.7,the resin had better alkali developable. Photoimage etching ink made up by alkali developable novolak epoxy acrylic resin had better alkali developable.  
        关键词：Epoxy acrylic resin;Alkali developable;Photoimage;Etching;UV curing material   
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        发布时间：2023-04-07
      • ZHANG Yingfa,LIU Zhenhao,YIN Xuejun
        Vol. 17, Issue 4, Pages: 225-230(1999)
        摘要：The tension adjuster is an important equipment in the transport system at the work line of electron beam radiation cross-linking wire and cable to realize the velocity synchronism. There are many kinds of the adjuster. By putting various adjusters together properly,we can keep the line work stably and raise the quality of the product. Tow kinds of standing adjuster and their mechanism are introduced in this paper. Also the corresponding figures and formulas are shown.  
        关键词：Tension adjuster;Velocity synchronism   
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        发布时间：2023-04-07
      • XU Ling,William Lee,Takanobu Sugo,Keizo Makuuchi
        Vol. 17, Issue 4, Pages: 231-238(1999)
        摘要：Two kinds of monomer (SSS and VBTAC) containing ion-exchange groups were cografted with HEMA onto HDPE membrane respectively by pre-irradiation grafting. Thus we obtained ion-exchange membranes with anti-bacteria function. The grafted membranes had good hydrophilicity compared with the hydrophobicity of the base film. The research was focus on 3-point: (1) Study the process of the grafting reaction, structure of the grafted membranes, chemical and physical properties of the grafted membranes. (2) Quantitative study of the hydrophilicity of the grafted membranes, evaluate the hydration number and surface free energy of the membranes. (3) Study the antibacterial activity of the grafted membranes. The antibacterial ability of the VBTAC membrane was so good that it would be fit for an antibacterial material.  
        关键词：Radiation-induced grafting;Functional membranes;Ion-exchange membranes   
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        发布时间：2023-04-07
      • XU Yeping,SONG Qinhua,MA Xingxiao,WANG Wenfeng,YAO Side
        Vol. 17, Issue 4, Pages: 239-241(1999)
        摘要：Photochemical reactions of 4-nitroquinoline 1-oxide (4NQO) with D-methionine (Met) and its dipeptides have been studied by using 248nm laser flash photolysis technique. Triplet state of 4NQO can be quenched by Met and its dipeptides, and produce radicals via electron transfer between triplet excited state of 4NQO and Met-containing compounds.  
        关键词：4NQO;Laser flash photolysis;Electron transfer;Excited triplet state   
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        发布时间：2023-04-07
      • SONG Qinhua,XU Yeping,LIN Weizhen,YAO Side
        Vol. 17, Issue 4, Pages: 242-244(1999)
        摘要：The photochemical reaction processes of triplet acetone with a peptide containing tryptophan and tyrosine residues (Trp-Tyr) were investigated in neutral aqueous solution using KrF (248nm) laser flash photolysis. Triplet acetone induced radical transformation: Trp/N•-Tyr→Trp-Tyr/O• was observed directly, and the transformation resulting from intramolecularelectron transfer was suggested.  
        关键词：Peptide;Triplet acetone;Laser flash photolysis;Electron transfer   
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        发布时间：2023-04-07
      • MA Shumei,LIU Xiaodong,YAO Yuan,YU Hongchen
        Vol. 17, Issue 4, Pages: 245-248(1999)
        摘要：Experiments with liquid single layer culture and semisolid culture in vitro were performed to evaluate the effect of low dose radiation (LDR) on bone marrow stromal progenitor cells. It was found that after the treatment of LDR the proliferation function of CFU-F increased, the supporting effect of CFU-F on CFU-GM and the adhesive capacity for bone marrow cells enhenced,especially in the groups treated with 50mGy and 75mGy. The results confirmed the homesis effect of LDR on bone marrow stromal progenitor cells.  
        关键词：CFU-F;LDR;Radiative effect;Adhesive capacity   
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        发布时间：2023-04-07
      • ZHANG Huaming,LI Xiurong,YANG Kebin,XIONG Ruilin,CHEN Chuan,XU Jiajing
        Vol. 17, Issue 4, Pages: 249-251(1999)
        摘要：Radiation effect of PA610 with polyfunctional monomer-trially isocyanurate (TAIC) was studied.The results showed that crosslinking effect of EB radiation on PA610 is obvious.After the PA610samples were radiated by EB, dosage 75kGy, the physical characters of PA610 materials were greatly improved,especially their tensile strength being increased about 18% and their impact strength about 50%,but their water and lubricant absorption were decreased. So, EB radiation can enhance PA610 materials physical strenth,resistance to solvents and water and increase their thermal-deformation teperature.  
        关键词：Polyamide610;EB radiation;Composite specification   
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        发布时间：2023-04-07
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