最新刊期
      期 4 ， 1991
      • Liu Songqing,Wang Fengju,Zhao Jun,Liu Junchen
        Vol. 9, Issue 4, Pages: 193-197(1991)
        摘要：Pilose antler is a kind of animal medicine and easy destroied by insects. In this paper, radiation to sterilize the pilose antler was carried out the process by means of γ-rays. The results illustrate that, the survival rates of insects and molds are roughly zero and 0.1% respectively under 2.5×103Gy γ-rays. There are not any remarkable changes of 17 sorts of amino acids and fatty acids. Toxicity test for the radiated pilose antler was also carried out. Therefor, the quality of pilose antler has not been influenced by irradiation.  
        关键词：Pilose antler;Pilose kindney;Pilose tail;γ-irradiation;Biopotency   
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        发布时间：2023-04-23
      • Ma Yuguang,Yang Meiling,Shen Jiacong,Lin Dehou
        Vol. 9, Issue 4, Pages: 198-202(1991)
        摘要：The PTFE films irradiated by Ar plasma were studied by using the method of ESR spectrometer. The peroxide free radicals were found on the surface of PTFE after plasma irradiation, which existed in the layer of some thickness of the surface. These free radicals were quite stable at room temperature. But when density of peroxide free radicals on the PTFE surface was big enough, terminational reaction between the peroxide free radicals cound happen and endoperoxides were formed on the PTFE surface. Also the density of peroxide free radical decreased with increasing temperature and underwent a sudden change with temperature reaching 399 K— the glass transition temperature of PTFE. The peroxide free radicals can be caught by free radical catcher PBN to form a stable free radical, also can react with MMA to form grafting layer.  
        关键词：Plasma;PTFE;Peroxid free radical;ESR   
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        发布时间：2023-04-23
      • Huang Jinzhong,Liu Jinwen,Wang Lianzhi,Gao Yulin,Wang Weiping,Liu Ruichun
        Vol. 9, Issue 4, Pages: 203-205,213(1991)
        摘要：This paper reports micronucleus test for studying cytogenetic effects. The patients were treeted by autohemotransfusion, after UV. radiation The results showed that there is no significant increase in the frequencies of micronucleus in lymphocyte, whereas the lymphocytic ability of proliferation was inhibited.  
        关键词：Autohemotransfusion;Frequency of micronucleus;UV radiation.   
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        发布时间：2023-04-23
      • Yang Lixi,Zheng Xiulong
        Vol. 9, Issue 4, Pages: 206-209,218(1991)
        摘要：In this paper it is reported that the recovery from 6—12 Gy X-ray irradiation-induced potentially lethal damage (PLD) in plateau-phase V79 cells, following incubation for 2—6h postirradiation was observed. The survival ratio was 1.5—2.0. While using nontoxic concentration below 4 mmol/L of metronidazolamic acid (CM), the significant inhibiting effects of CM on 6—12 Gy X-ray induced PL-DR was evaluated. The repair inhibition factor (RIF) ranged from 1.31—46.30. However, the CM treatment with a 6 h incubation following 12 Gy radiation showed the highest RIF which were 14.03, 28.16 and 46.30 for 0.5, 1.0 and 2.0 mmol/L CM respectively. These results indicate that CM strongly inhibits radiation induced PLDR and the effectiveness depends on CM concentration, postirradiation incubation time and the radiation doses, suggesting that CM fixes the X-ray induced PLD, and thereafter prevents its repair. The molecular mechanism of CM inhibiting effects on PLDR is discussed.  
        关键词：CM;Potentially lethal damdge recovery (PLDR);Repair inhibition factor (RIF);V79 cells   
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        发布时间：2023-04-23
      • Xu Hui,Yi Lukang
        Vol. 9, Issue 4, Pages: 210-213(1991)
        摘要：The effect of ADP-ribosylation on transcriptional activity in isolated nuclei from spleen of adult male rats irradiated with 8 Gy gamma-rays was studied. The results showed the activities of RNA pol(Ⅰ+Ⅲ) were all inhibited by ADP-ribosylation and this inhibition was lost in the presence of 3-AB, a specific inhibitor of ADPRT. It confirmed the effect of ADP-ribosylation. The fact that ADPRT activity decreased within 4 hours after irradiation and subsequently restored entirely after 18 hours showed irradiation of 8 Gy gamma ray inhibited the ADPRT activity and the effect of irradiation disappeared quickly.  
        关键词：ADP-ribosylation;Transcription;Irradiation;RNA polymerases   
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        发布时间：2023-04-23
      • Yao Suyan,Zhang Chaoyang,Dai Lianlian,Gao Changwen
        Vol. 9, Issue 4, Pages: 214-218(1991)
        摘要：Relationship between aneuploid, dominant lethal mutaions and doses in young female mice induced by low doses γ-rays was examinated. The results suggest that the frequencies of aneuploid of embryos were not found increase at 0.15 Gy, but increases at over 0.50 Gy after irradiation in groups. The frequencies of aneuploid and dominant lethal mutations were increased with increasing doses and fitted linear relationship.The dose-response relationship of trisomic was not significant. The frequency of dominant lethal mutations induced by 60Co γ irradiation is 5.59% .The effect of dominant lethal mutation is higher than that of the aneuploid.  
        关键词：Embryo;Aneuploid;Dominant lethal mutations;γ-rays   
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        发布时间：2023-04-23
      • Cao Jin,Chen Pin,Yu Yi
        Vol. 9, Issue 4, Pages: 219-222(1991)
        摘要：The paper decribed the preparation of immobilized cells membranes with E. Coli by radiation technique. The nylon 6 was grafted with HEMA, which as matrix to prepare immobilized cells membranes with E. Coli. by radiation entrapment at low temperature. The results showed that the retentive activity possessed a maxium value for membranes with E. Coli. when the irradiation dose was at 10—12 kGy, the entrapped cells has 2.3 g/ml at 50% HEMA concentration, the optimum pH and optimum temperature for membranes with E. Coli. are as same the original cells.  
        关键词：E. Coli.;Radiation immobilization;HEMA;Radiation grafting;Radiation entrapment   
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        发布时间：2023-04-23
      • Yang Zhiyuan,Sun Shiquan,Liu Hechen
        Vol. 9, Issue 4, Pages: 223-227(1991)
        摘要：Lyophylized irraddiation sterilized nerve gafts in rabbits were used in allogeneic nerve transplatation. The result show that about 76% of experimental rabbits had fairly well morphologic (microscopic and electron microscopic) and electrophysiological recovery 3 month after operation. Preservation of neurilemmal tubes in nerve grafts, repopulation of Schwann cells in this tube and supression of immune rejection are the key pionts in allogenic nerve transplantation.  
        关键词：Nerve transplantation;Tissue bank;Irradiation sterilization;Sciatic nerve of rabbit   
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        发布时间：2023-04-23
      • Xia Shouxuan
        Vol. 9, Issue 4, Pages: 228-232(1991)
        摘要：In the recent years the study of DNA damage and repair in the mammalian cells has gone deeply at gene level and got the following advances: (1)For a long time DNA has been considered to be an uniform unit in case of damage and repair. Now this concept should be replaced by the non-random distribution of damage and heterogenous repair in the genome. These would allow us to study cellular mutagensis, carcinogenesis, aging and dying processes in great detail, and would be beneficial to the elucidation of mechanisms of radiation sickness and chemical toxicology. (2) The advent of new techniques in molecular biology has made it possible to isolate and clone the human DNA repair genes. Up to now more than ten human DNA repair genes have been cloned and these works would have an important impact on the theoretical and practical study in this field. Because DNA repair system is very complicate, voluminous work should be done in the future. (3) The technique of gene transfer has been efficiently used in the study of DNA repair in mammalian cells and has made great contribution in the cellular engineering. It could modify the genetic behavior of the gene-accepting cells, and enhance the DNA repair ability to physical and chemical damages. Human gene therapy for DNA deficient diseases is now on the day.  
        关键词：DNA damage and repair;Gene isolation and cloning;Gene transfer;Gene therapy   
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        发布时间：2023-04-23
      • Lu Xiaohong,Ha Hongfei,Wu Haiyan,Wu Jilan
        Vol. 9, Issue 4, Pages: 233-237(1991)
        摘要：Radiation-induced grafting is a potential method for modification of polymers, for example, highly hydrated polymeric surfaces may be biocompatible and thomboresistant. It is well known that addition of mineral acid to some grafting solution enhanced the radiation grafting yield of some polyolefins. But it turns out not to be the case in all conditions. Some monomers (such as N-VP)can be grafted onto some polymers(such as SPEU)only in basic medium. That means that the acid effect in grafting systems depends on many effects such as component of matrix, type of monomers and solvents, method of irradiation, absorbed dose and so on. In this work, the cuves of grafting yield as a function of absorbed dose showed that there were about two regions of dose: lower than 5 kGy, the grafting yield of AA on silicone rubber was enhanced by acid: the other region, dose growing up to about 13 kGy, the opposite results were obtained. In acid enhancing region of dose the tendency of grafting yield as a function of dose rate and monomer concentration was not influenced by whether the acid existed. The mechanism was discussed as well.  
        关键词：Silicone rubber;Acrylic acid;Acid effect;Simultaneous irradiation graft   
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        发布时间：2023-04-23
      • Zhao Bingxi,Tian Minquan,Chen Dayong,Han Zhewen
        Vol. 9, Issue 4, Pages: 238-242(1991)
        摘要：The radiation polymerization of triethyltin methacrylate (TETM)was introduced in this paper, and the effect of temperature on the radiation polymerization of TETM has been researched. The results show that both the radiation polymerization rate of TETM and the molecular weight of poly (triethyltin methacrylate)(PTETM) increase as the polymerization temperature increases. The overall activation energy for the rate of radiation-polymerization ER was determined to be 18.0 kJ•mol-1 and the overall activation for the degree of radiation polymerization is 13.6 kJ•mol-1. the thermal preperties of PTETM have also been investigated.  
        关键词：Radiation polymerization;Triethyltin methacrylate;Activation energy   
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        发布时间：2023-04-23
      • Zhou Heping,Zhou Maotang,Wang Shicai,Chen Jie
        Vol. 9, Issue 4, Pages: 243-245,242(1991)
        摘要：In a capacitively coupled discharge apparatus with external electrodes, vinyldimethylethoxysilane were polymerized, and the effects of system pressure, discharge power and substrate distance on the polymerization rate were studied. The polymer structure was researched by IR spectroscopy and XPS, some properties of the polymer such as thermostability and surface characteristics were also determined.  
        关键词：Vinyldimethylethoxysilane;Plasma polymerization;Contact angle   
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        发布时间：2023-04-23
      • Tang Beilin,Kanako Kaji,Iwao Yoshizawa,Choji Kohara,Motoyoshi Hatada
        Vol. 9, Issue 4, Pages: 246-251(1991)
        摘要：The effects of electron beam irradiation on polyethylene foam of open cell type have been studied. Experiments for determining of gel fraction and physical-mechanical properties of irradiated polyethylene foam of open cell type as a functoin of dose, respectively, were carried out. The dimensional stability of irradiated specimens at elevated temperatures also was measured. It was found that tensile strength did not change and gel fraction increased when the specimen was irradiated in nitrogen atmosphere with increasing dose up to 300 kGy. The result shows that dimensional stability of polyethylene foam of open cell type after being kept in an oven at 70℃ and 110℃ for 22 h is improved by irradiation in nitrogen atmosphere. The similar results of irradiated EVA foam of open cell type to irradiated PE foam of open cell type were obtained.  
        关键词：PE;EVA Foam;EB irradiation;Gel fraction;Physical-mechanical properties;Dimensional stability at elevated temperature   
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        发布时间：2023-04-23
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