最新刊期
      期 1 ， 2005
      • WEN Xiaoqian,LIU Fenju
        Vol. 23, Issue 1, Pages: 1-5(2005)
        摘要：Glioma is the most common neoplasm in brain, which is commonly considered as the tumor tissues with high radioresistance. There have been enhanced research activities in recent years to explore molecular mechanisms of apoptosis induced by ionization radiations, and many researchers have focused their efforts on the radioresistance mechanisms of glioma cells, in an attempt to look for the resistance genes, which could be reverted, to imporve radiosensitivity of tumor cells and the therapeutic efficacy. The paper gives a review on progresses of the studies on the gene and enzyme related to the radioresistance of glioma, and the external environment and other issues about reversion of the radioresistance.  
        关键词：Glioma;Radiotherapy;Radioresistance;Reversion gene   
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        发布时间：2023-03-30
      • WANG Lixin,YU Kun,LUO Shikai,LI Zhe,LIU Ning
        Vol. 23, Issue 1, Pages: 11-14(2005)
        摘要：Fluoropolymers F2311 and F2314 samples were irradiated by neutrons of 1.23 MeV in average energy up to fluences of 1.5×1013 / cm2 and 2.5×1013 / cm2, and their static and dynamic mechanical properties and molecular weight were determined. It indicated that static mechanical properties of the F2311 samples and tensile intensity of the F2314 samples increased with the neutron fluence, whereas compression intensity of the F2314 samples decreased with the neutron fluence. Molecular weight of both the fluoropolymers increased with the neutron fluence. Little changes were found with dynamical properties of the F2311 samples, whereas dynamical properties of the F2314 samples decreased with the neutron fluence.  
        关键词：Neutron;Irradiation;Fluoropolymers;Mechanical properties   
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        发布时间：2023-03-30
      • ZHANG Wenyi,JIAO Ling,HOSHI Masaharu
        Vol. 23, Issue 1, Pages: 15-18(2005)
        摘要：The work is for a better understanding of relative biological effectiveness (RBE) of 252Cf fission neutrons. The frequency of micronuclei induced in the root-tip cells of onion seedlings after irradiation as dry dormant seeds by unit dose of 252Cf neutron-γ mixed irradiation is different from that by 60Co γ-ray irradiation. The frequency of micronuclei induced by unit dose of 252Cf neutron-γ mixed irradiation and 60Co γ-ray irradiation are 1.84±0.10 and 0.022±0.002 (%Gy-1), respectively; and the frequency of micronuclei induced by unit dose of 252Cf fission neutrons is 2.74±0.15 (%Gy-1). The RBE values for 252Cf neutron-γ mixed irradiation and 252Cf fission neutrons are 84±9 and 124±13, respectively. The frequency of micronuclei induced in the root-tip cells of Allium cepa onion seedlings irradiated as dry dormant seeds by unit dose of 252Cf neutron-γ mixed irradiation is about 84 times as that by 60Co γ-ray irradiation. The findings suggested that repair efficiency of DNA damage induced by neutrons might be different from that by γ-ray.  
        关键词：252Cf;Neutron;Micronucleus;Onion seed;Relative biological effectiveness (RBE)   
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        发布时间：2023-03-30
      • WANG Min,YANG Ruiyuan,ZHU Zhiyuan,WANG Wenfeng
        Vol. 23, Issue 1, Pages: 19-24(2005)
        摘要：Degradation of 4-chlorophenol in aqueous solutions has been studied by γ-ray irradiation of 2.2−14.9kGy. Absorption spectra, chemical oxygen demand (COD) and Cl removal efficiency of the sample solutions were investigated under different irradiation conditions. COD removal efficiency and the Cl removal efficiency could be 65.8% and 100%, respectively. In addition, the results show that H2O2 plays an important role in the radiolysis degradation of 4-chlorophenol. It is concluded that the irradiation technology is an effective method for treatment of waste effluents with chlorophenol.  
        关键词：γ-ray irradiation;4-chlorophenol;Degradation;Chemical oxygen demand;Cl removal   
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        发布时间：2023-03-30
      • LI Jing,HOU Zhengchi,XIE Leidong,ZHANG Fengying,DENG Bo
        Vol. 23, Issue 1, Pages: 25-28(2005)
        摘要：Grafting methyacrylic acid onto poly(ether sulfone) membranes was realized by means of simultaneous irradiation in liquids. The modified membranes with different grafting ratios were obtained by changing the concentration of methyacrylic acid. It was shown that the grafting ratio increased lineally as the monomer concentration was less than 10% and hydrophilicity of the membranes was improved with increasing grafting ratios.  
        关键词：Radiation grafting;Hydrophilicity;Poly(ether sulfone);Methyacrylic acid   
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        发布时间：2023-03-30
      • XU Yunshu,GUO Gaopin,FU Yibei
        Vol. 23, Issue 1, Pages: 29-34(2005)
        摘要：Polyfunctional monomers (PFM) were important sensitizers for radiation crosslinking applications. It is supposed that free radicals formed initially on the main chains of the irradiated polymer initiate grafting polymerization of the double bonds in the PFM molecules and form the grafted special chains which crosslinked together the polymer’s main chains. Based on this simplified sensitized crosslinking model and other necessary assumptions, an expression correlates crosslinking density (q), absorbed dose (D) and PFM content (C0) was derived. Analyzing results of published data demonstrated that q values of polyethylene-co-propylene (EPR), polyisoprene (IR), polychloroprene (CR) and polystyrene-co-butadiene (SBR) increase linearly with D and C0, and the q of IR increases linearly with .  
        关键词：Elastomer;Radiation crosslinking;Polyfunctional monomer;Crosslinking density   
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        发布时间：2023-03-30
      • HOU Zhengchi,SUN Dakuan,QIN Zongying,JIN Jiang,ZHU Liandi,YAO Side,SHENG Kanglong
        Vol. 23, Issue 1, Pages: 35-39(2005)
        摘要：Fresh pork loin samples, protein enzyme inactivated at (72 ± 3)℃ and vacuum packaged, were irradiated to up to 45kGy at -20℃ by 60Co γ-rays. The irradiated samples were examined by various kinds of method to study high dose irradiation effects of sensory changes (meat color and off-odor), transverse shearing strength, weight loss in steam cooking, volatile organic compounds, and lipid oxidation. The results showed that the high dose irradiation produced no serious effects to the pork loin samples, and volunteer responses showed fine acceptability to the irradiated meat.  
        关键词：Radiation processing;Volatile organic compounds;Lipid oxidation;Irradiation off-odor   
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        发布时间：2023-03-30
      • GE Xuewu,WU Dazhen,CHU Songnan,ZHANG Zhicheng
        Vol. 23, Issue 1, Pages: 40-44(2005)
        摘要：By combining dispersion polymerization and γ-ray irradiation, γ-Fe2O3/polystyrene (γ-Fe2O3/PSt) magnetic composite microspheres were produced at room temperatures under ambient pressure via one-step method or two-steps method. Formation mechanisms of the magnetic composite microspheres were studied. The magnetic composite microspheres were characterized and studied with transmission electron microscope (TEM), electron diffraction (ED), X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy. The results show that the magnetic composite PSt microspheres containing homogeneously dispersed γ-Fe2O3 nanoparticles and the acrylic acid in the system played an important role in the synthesis of the magnetic composite microspheres.  
        关键词：60Coγ-ray irradiation;Dispersion polymerization;γ-Fe2O3/PSt magnetic composite microspheres   
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        发布时间：2023-03-30
      • SHEN Bo,SHEN Bing
        Vol. 23, Issue 1, Pages: 45-48(2005)
        摘要：To analyze the genomic instability induced by γ-rays, cytokinesis-block MN assay was employed to investigate the gene damage of cells and their progeny cells exposed to radiation. The micronucleus frequency were related to the irradiation dose and decreased as the culture time lengthened. There was a correlation between the micronucleus frequency and the initial dose after the second irradiation. The micronucleus frequency may be causally related to radiation-induced genomic instability which is expressed as chromosomal damage leading to micronuclei.  
        关键词：Genomic instability;Cytokinesis-block MN assay   
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        发布时间：2023-03-30
      • XIA Jingguang,LI Wenjian,WANG Jufang,GUO Chuanling,JIN Xiaodong,GAO Qingxiang
        Vol. 23, Issue 1, Pages: 49-52(2005)
        摘要：Human hepatoma cells hepG2 were irradiated twice by 60Co γ-rays with a priming dose of 5cGy and a higher dose of 3Gy performed 4h or 8h after the low dose irradiation. Effects of the priming dose irradiation on cell cycle arrest caused by high dose were examined with flow cytometry. Cells in G2/M phase accumulated temporarily after the 5cGyirradiation, and proliferation of tumor cells was promoted significantly by the low dose irradiation. After the 3Gy irradiation, G2 phase arrest occurred, and S phase delayed temporally. In comparison with 3kGy irradiation only, the priming dose delivered 4h prior to the high dose irradiation facilitated accumulation of hepG2 cells in G2/M phase, whereas the priming dose delivered 8h prior to the high dose irradiation helped the cells to overcome G2 arrest. It was concluded that effects of the priming dose treatment on cell cycle arrest caused by high dose irradiation were dependent on time interval between the two irradiations.  
        关键词：Low dose radiation;Cell cycle arrest;Hepatoma cells   
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        发布时间：2023-03-30
      • WANG Zhidong,CHEN Xiaohua,DONG Bo,ZHANG Junquan,RAO Yalan,GAO Ronglian,HOU Lili,MAO Bingzhi
        Vol. 23, Issue 1, Pages: 53-56(2005)
        摘要：To explore the early diagnostic factors, new therapeutic targets and mechanisms of acute radiation disease. Proteomic changes of the serum of irradiated mice were studied using 2-DE and Q-TOF-MS approaches. One higher level expressed protein after the irradiation was found, and it was identified as α chain of haptoglobin by Q-TOF–MS. We confirmed the result by Western blotting with anti-haptoglobin antibody. Haptoglobin may involve in the process of acute radiation injury.  
        关键词：Acute radiation injury;2DE;Q-TOF-MS;Hhaptoglobin   
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        发布时间：2023-03-30
      • CUI Yufang,DING Yanqing,XU Han,JIANG Zhujun,JIN Wei,MAO Binzhi
        Vol. 23, Issue 1, Pages: 57-61(2005)
        摘要：By using TdT-mediated dUTP nick end labeling (TUNEL), in situ hybridization and immunohistochemical method of alkaline phosphatase, we observed the apoptotic dynamic changes of mouse lymph node lymphocyte after lethal dose γ-ray irradiation, and its relationship to the expressions of Bax, Bcl-2 and Bcl-XL proteins and bax, bcl-2 mRNAs.The results showed that 24h after irradiation, apoptotic index of lymph node lymphocytes increased swiftly, with a positive correlation to the doses within 6—12Gy, whereas no relationship was observed for 15Gy and 20Gy irradiation groups. Twenty-four hours after 6Gy irradiation, the lymphocytes apoptosis reached a maximal level and decreased thereafter. However, up to 6 and 12 months after the 6Gy irradiation, the apoptotic index was still higher than the control group. Twenty-four hours after the irradiation, the expression of lymphocyte Bax protein enhanced immediately, with the 12Gy group being highest value, whereas such a dose-effect was not found for the 15Gy and 20Gy groups. While the expressions of Bcl-2 and Bcl-XL proteins decreased evidently 24h after the irradiation, the analysis on bax and bcl-2 mRNA showed also a similar tendency. It was suggested that apoptosis was an important way of lymphocyte death pathways after ≤12Gy irradiation. The up-regulation of Bax and down-regulation of Bcl-2 or Bcl-XL indicate that they play an important role in the apoptotic regulation of lymphocytes induced by lethal dose radiation.  
        关键词：γ-ray irradiation;Lymph node;Apoptosis;Bax;Bcl-2;Bcl-XL   
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        发布时间：2023-03-30
      • YANG Mingcheng,ZHU Jun,CHEN Haijun,LIU Kebo,ZHAO Huidong,ZHANG Chuanguo
        Vol. 23, Issue 1, Pages: 62-64(2005)
        摘要：Nylon composite films, with five layers of nylon-6, adhesive PE, PE, adhesive PE and nylon-6, were crosslinked by 60Co γ-ray irradiation to 10—50kGy. Effects of irradiation dose on properties of the nylon-6 composite films were studied. The results showed that mechanical properties of the nylon-6 composite films could be improved to certain extent, while keeping original separation properties. In particular, the contraction ratio was distinctly reduced.hence an improved dimensional stability in applications of the nylon-6 composite films.  
        关键词：Radiation crosslinking;Nylon-6 composite film;Dimensional stability   
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        发布时间：2023-03-30

        综述

      • HE Linfeng,ZHOU Ruimin,XIN Lihui,Adeleke O. Francis,PAN Chenwei
        Vol. 23, Issue 1, Pages: 6-10(2005)
        摘要：A new method, using electron beam, has been successfully developed to prepare nickel nano-particles at room temperature under ambient pressure, without any catalyst. The structure, morphology, size, size distribution, optical properties, magnetic properties and the melting point have been characterized by X-ray diffraction (XRD), laser scattering particle size distribution analysis (LSPSDA), transmission electron microscopy (TEM), ultraviolet-visible spectrophotometer (UV-vis), vibrating sample magnetometer (VSM) and differential scanning calorimeter (DSC), respectively. The LSPSDA and TEM results show that average size of the nickel nano-particles is about 39 nm, which is in agreement with the calculated value from XRD using Scherer formula.  
        关键词：Nano-materials;Nickel nano-particle;electron beam;radiation;electron accelerator   
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        发布时间：2023-03-30
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