最新刊期
      期 4 ， 1986
      • Meng Ziqiang
        Vol. 4, Issue 4, Pages: 1-7(1986)
        摘要：DNA hybridization with nuclear RNA(nRNA) synthesized immediately after 60Co Gamma-irradiation in the spleen cells freshly isolated from inbred line 615 mice was investigated, using the technique of Gillespie and Spiegelman (J. Mol. Biol., 12, 829. 1965) .In RNA/DNA hybridization percentage experiment, it was showed that the hybridization of normal DNA with labelled nRNA synthesized in irradiated cells reached the saturation point at a much faster rate than with labelled normal nRNA (fig. 1) . The hybridization percentage of nRNA synthesized in irradiated cells was higher than that of normal nRNA during the different reaction time before the saturation point of DNA with nRNA synthesized in irradiated cells, but it was lower than that of normal nRNA after the point. It was assumed that the transcription of some base sequences in the zone of high repetitive DNA sequences was stimulated, however, the transcription of some base sequences in the zone of low repetitive DNA sequences was seriously inhibited.Measurements of the exhaustion rates of pulse-labelled nRNA were carried out as described by Greene and Flickinger Biochim. (Biophys. Acta, 217, 447. 1970) .In these studies, pulse-labelled nRNA synthesized in unirradiated and irradiated cells were compared by exhaustion with DNA at hybridization time of 4 or 24 hours, When the hybridization time was 4 hours, the nRNA synthesized in irradiated cells displayed a faster exhaustion rate than the control nRNA. But if the hybridization time was 24 hours, the exhaustion rate of nRNA synthesized in irradiated cells reduced. These results demostrated that Gamma-irradiation changed the proportion of transcription of some nRNA species and implayed that the sensitivities of the transcription activeties of the different repetitive DNA sequences to Gamma-irradiation were different, and so were the transcription activeties of the different base sequences in the same repetitive DNA sequences. We suggested that Gamma-irradiation stimulated the transcription activeties of some base sequences in the zone of high repetitive DNA sequences which were low before Gamma-irradiation, but Gamma-irradiation inhibited the transcription activeties of some base sequences in the zone of high repetitive DNA sequences which were high before the irradiation.  
        关键词：Hybridization;DNA;RNA;Gamma-irradiation;Spleen cells   
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        发布时间：2023-04-23
      • Zhou Xiangyan,Dong Jinchan
        Vol. 4, Issue 4, Pages: 8-11(1986)
        摘要：Female and male mice were exposed to 60Co gamma rays for 10 days, the accumulative doses were 0.396-2.024 and 0.462-2.552 Gy respectively. The number of dominant lethal mutations was calculated as follows: PRE=CL-(ED+LD+VIA) . The results showed that Preimplantation Loss (PRE) ranged from 1.222 to 3.714 for female mice and 0.0345 to 2.2308 for male mice in both cases a linear dose-effect relationship was observed. The PRE of oocytes is 1.66 times higher than that of spermatids.  
        关键词：Tritiated Water;60Co gamma rays;dominant lethal mutation;preimplantation loss   
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        发布时间：2023-04-23
      • Meng Xiangqin
        Vol. 4, Issue 4, Pages: 12-17(1986)
        摘要：The feasibility of the dosimetry based on electron spin resanance analysis of 60Co γ-ray-induced free radicals in d-glucose has been studied. A relative measurement method, a technique of preparation samples, a calibration procedure and a dose assessment equation are presented in the paper.determining 60Co γ-ray absorbed dose using d-glucose/ ESR free radical dosimeter there are very good linear response characteristic in 10~3×104Gy range; the dispersion of the response among the tested specimens is less than 3%; under the dried atmosphere of 4℃, the stability of the ESR signals of samples is satisfactory for two months which relative standard deviation of the variations is about 2%. Dosimeter samples, composisting of small pellets of microcrystalline d-glucose in paraffin, are firm enough for use, tissue equivalent and insensitive to surface contaminations.D-glucose/ESR free radical dosimetry is testified to a better high-dose measuring technique. It can be used widely to determine the dose in radiation research and radiation processing.  
        关键词：Dosimetry;D-glucose;ESR;Free radical   
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        发布时间：2023-04-23
      • Yang Jiakuan,Lin Weiqi,Cai Rongmei,Cui Shengqing
        Vol. 4, Issue 4, Pages: 18-22(1986)
        摘要：This paper deals with the observation of micronuclear incidence in PCE bone marrow of Wistar rats. Two groups of rats were fed irradiated foods for 110 days and 150 days respectively. One was fed irradiated foods, in which irradiated foods occupied 80% of total food. Another was that in which irradiated vegetables being added in 3%. The radiation dosage was 2 kCy (200000 rads) .In addition, there were negative control rats fed general foods and positive rats treated by cyclophosphamide or whole body irradiation with 2 Gy (200 rads) . In this experiment, Giemsa staining, Harris hemotoxylin restaining and acridine orange fluorescence staining were used. From the results, it was indicated that the incidence of PCE with micronuclei in bone marrow of rats was not increased in the animals feeding mixed irradiated foods or in irradiated vegetables.  
        关键词：Mixed Irradiated Foods;Irradiated Vegetables;Micronuclei;Wholesomeness   
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        发布时间：2023-04-23
      • Zao Benxi,Murat,Zun Sionbu,Han Zhewen
        Vol. 4, Issue 4, Pages: 23-28(1986)
        摘要：This paper introduced the Radiation Polymerization of Polytributyltin Methacrylate (PTBTM) and its kinetics. The results are shown Fig1~6. The relationship between rate Rp and Concentration of TBTM are shown Rp=Kp[TBTM]2, The relation dose rate I and rate Rp are shown Rp=K'pI0.66. The overall activation energy of polymerization Ea is 1.32 J/mol. This paper also investigates the machine of polymerization for TBTM.  
        关键词：Radiation polymerization;Polymerization rate;Conversion rate;Radical Tributyl Tin Methacrylate;Activation energy of polymerization   
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        发布时间：2023-04-23
      • Lin Nianyun,Li Xuepeng,Tu Tiecheng,Dong Jirong
        Vol. 4, Issue 4, Pages: 29-33(1986)
        摘要：In order to investigate the charge transfer protection mechanism on DNA and dTMP another hydroxy cinnamic acid derivative-sinapine has been studied. Sinapine also belongs to phenyl substituted unsaturated carboxylic acid and its EA(εLEMo: 1.81 eV) is very close to that of caffeic acid εLEMO : 1.79 eV) but its IP(εHOMo:-11.27 eV) is much lower than that of caffeic acid (εHOMO: -11.74 eV) , therefore in comparision with caffeic acid sinapine exert stronger protection effect on DNA, for example, ESR spectrum from DNA-sinapine with more minor molar ratio of protector to nucleotide of DNA(1:8) than that of DNA-caffeic acid (1:4) revealed the characteristic similar to that from sinapine alone irradiated and recorded at 77 K. After annealing at room temperature the ESR pattern changed into that from sinapine alone with clear baseline demonstrating no trace signal from 5-thymyl radical i. e. stronger protective effect by sinapine.  
        关键词：Hydroxy cinnamic acid derivative;Sinapine;Charge transfer protection;ESR;DNA   
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        发布时间：2023-04-23
      • Cheng Kwangrun,Yang Chuyao,Wang Mingjun
        Vol. 4, Issue 4, Pages: 34-37(1986)
        摘要：The change in structure of irradiated primaquine phosphate with doses of 0.75-10 Mrads don't be observed. The transfer action of energy of quinolyl in irradiation process is considerable due to quinolyl resonance stabilization. As a result of this action, during irradiated PVA for contained primaquine phosphate, radiation degradation of PVA can be decreased, but the mechanism of degradation don't be influenced. The effects of the different content of primaquine phosphate on various parameters of degradation have been studied in this work and the relationship of straight line is obtained in them.  
        关键词：primaquine phosphate;Quinolyl resonance stabiliza-tion;Transfer of energy;Radiation degradation of PVA;Actin of postponemet;Parameter of degradation   
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        发布时间：2023-04-23
      • Zhou Xiangyan,Dong Jinchan,Peng Xiaoping
        Vol. 4, Issue 4, Pages: 38-42(1986)
        摘要：Four groups of male LACA mice were injected intraperitoneally with radioactivity of HTO (Bq×105/g•b•w) :8.4、16.8、29.3、45.2, respectively; the accumatve doses absorbed by testis in 10 days aftr injecton were 0.19, 0.38, 0.66 and 1.01 Gy accordingly. Meanwhile, three groups of male mice were exposed to 60co gamma rays for 10 days in decreasing dosage following the exponentially decreasing trend of tritium concentrations in testis; the accumulative doses were 0.743, 1.592 and 2.074 Gy, respectively. The preliminary results showed that the yield of induced dominant lethal mutations ranged from 0.086 to 0.149 for tritium treated animals, and that for gamma irradiated mice was 0.0436 to 0.303; in both cases a linear dose-effect relationship was observed. Based on the above experimental results, the estimated RBE value for tritium is 2.1.  
        关键词：Tritium beta rays;Dominant lethal mutations;RBE (relative biological effecteveness)   
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        发布时间：2023-04-23
      • Jin Yizun,J. Handman
        Vol. 4, Issue 4, Pages: 43-47(1986)
        摘要：One-electron reduction potential () is a measure of the electron affinity of the compound by pulse radiolysis at PH 7. The less negative the value, the greater is the electron affinity of the compound. Many studies supported that the electron affinity is related qualitativety to radiosensitization effectiveness. This paper describes the of some 3-nitro-7-azaindole derivatives.  
        关键词：One-electron reduction potential;Pulse radiolysis;Electron affinity;Radiosensitization effectiveness;3-nitro-7-azaindole.   
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        发布时间：2023-04-23
      • Ye Lianghua,Li Ping,Mei Zhoulei,Ye Yin
        Vol. 4, Issue 4, Pages: 48-51(1986)
        摘要：Linear polymethyl methacrylate undergoes main-chain scission when exposed to high energy radiation in air at room temperature. Changes in molecular weight were observed by measurements of intrinsic viscosity which give directly the viscosity average molecular weight MV. As a rule MV=1.9 Mn for this polymer in which case it is possible to obtain a direct relationship between MV and number average molecular weight Mn, this procedure gives information on number of radiation-induced fracture. Because the plot of 1/MV against dose is linear when the radiation dose is more than 5×105 rad, it may be concluded that radiation-induced fracture occurs at random and they are proportional to the dose. This may account in the yield of main-chain degradation, G(S) =1.0.Cross-linked long-chain polymethyl methacrylate also undergoes degradation when exposed to radiation in air at room temperature. By using two methods, namely the gel-sol distribution measurement and the average molecular weight between cross-links MC measurement, it was found that MC of this polymer linearly increasse and the gel fraction reduces with radiation in dose range 5×105~5×106 rad. These results show that degree of cross-linkng steadily decreases under radiation. When the radiation dose is more than 1×107 rad, the cross-linked polymer becomes linear polymer thoroughly.  
        关键词：Radiation degradation;Linear Polymethyl methacrylate;Cross-linked polymethyl methacrylate   
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        发布时间：2023-04-23
      • Chen Ruyan
        Vol. 4, Issue 4, Pages: 52-55(1986)
        摘要：This paper describes the observed phenomena of coloradion produced by gamma of irradiation in two type of silicate glasses, optical glass and natural crystal. The visible obsorption spectra and the heat stability of colour centres of the glasses after irradiation were compared. The types of colour centres in the glasses were analysed.  
        关键词：Visible absorption spectra;Heat stability of colour centre;Temperature for thermoluminescence peak   
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        发布时间：2023-04-23
      • Wang Cunda,Li Hao,Li Jianli,Wang Peng
        Vol. 4, Issue 4, Pages: 56-61(1986)
        摘要：Samples of Pure NaF, NaF : Mg++ and NaF : Mn++ Crystals have been irradiated by electron beam at different temperature. The time dependence of optical absorption spectra of these samples has been measured. It is observed that the kinetics processes of reduction and () * production involve four reactions : deionization of center and formation of F2 center; thermal decomposition of F2+ center and production of F center and F+ center conversion of into () * and direct composition of () * center for different doping concentrations and irradiation conditions, the different reactions will play the main role. It is apparent that () * center consists of center, certain irradiation demage and outer divalent impurity cation.  
        关键词：NaF Crystal; center;()* center;Electron irradiation;Kinetics process   
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        发布时间：2023-04-23
      • Shen Yu,Wang Jun,Li Yanchun,Mi Fushun,Su Xueqing
        Vol. 4, Issue 4, (1986)
        摘要：The use of Miso in conventional radiotherapy was unsatisfactory, owing to its high neurotoxicity. An upsurge in searching for high efficiency and low toxicity radiosensitizers through various ways is carrying out over the whole world.  
          
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        发布时间：2023-04-23
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