最新刊期
      卷 9 ， 期 2 ， 1991
      • Zhao Fang,Zheng Xiulong
        Vol. 9, Issue 2, Pages: 65-68(1991)
        摘要：The effects of a new radiosensitizing compound-metronidazolamic acid(CM) and its Ca+2 chelation compound (CMCa) on the DNase activity of mouse hepatic tumor (H22) cells were observed.The effects of CM, CMCa or Ca+2 at same molarity and their combination with γ-rays irradiation on DNase activity of H22 cells were also observed respectively. The results showed that CM could activate the DNase activity to be increased as CM concentration increased below 5 mmol/L. The highest DNase activity was activated by CM at 5 mmol/L. The degree of activation between CM and CMCa had no significant differente (p>0.05), whereas free Ca+2 alone had no effect. The activation of combined CM or CMCa and radiation groups were greater than that of each given independently (Fig. 3),they possessed a coordinate activation. However free Ca+2 still could not activate the DNase activity after γ-irradiation. From all the above results, it is suggested that CM or CMCa improved the tumor radiotherapeutic efficiency probable due to its activation the DNase activity of cancer cells which enhanced the DNA damage. It might be one of the radiosensitizing mechanism in tumor radiothorapy.  
        关键词：radiosensitizer;Metronidazolamic acid;H22 cells;DNase   
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        发布时间：2024-11-05
      • Murat,Liu Junchen,Liu Songqing,Wang Fengju,Zhao Jun
        Vol. 9, Issue 2, Pages: 69-73(1991)
        摘要：Petroleum sodium sulfonates can be producted by γ-radiation sulfochlorination of MPN. Value is proportional to inverse-square-root of radiation dose rate. According to Electron Spin Resonance, Nuclear Magnetic Resonace and GC/MS/DCS analyses, the radiation sulfochlorination mechanisms of MPN are proposed. There is a patential to synthesize sulfonates from relatively inexpensive MPN.  
        关键词：γ-radiation;Sulfochlorination;G Value;ESR;NMR;GC/MS/DCS   
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        发布时间：2024-11-05
      • He Zhongda,Li Shuzhong
        Vol. 9, Issue 2, Pages: 74-78(1991)
        摘要：This paper reports the structure and physical properties of γ-radiation crosslinked low density polyethylene (LDPE) and chlorosulfonated polyethylene(CSM) blends. The effect of γ-radiation on IR spectra and crystallinity of the blends was investigated. It was observed that the presence of the antioxidants depressed the oxidation of LDPE/CSM during irradiation by IR spectroscopic analysis. The mechanical, dielectric properties and thermal analysis spectra of γ-radiation LDPE/CSM blends were discussed.  
        关键词：Radiation crosslinking;LDPE;CSM;Blend;IR spectrum;Physical property   
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        发布时间：2024-11-05
      • Wang Xianli,Sun Shuqing,Wang Bin,Wang Mingdong
        Vol. 9, Issue 2, Pages: 79-82(1991)
        摘要：The chromosome damage caused by relative low doses (0.25, 0.50, 0.75 and 1.00 Gy) of X-rays was examined in secondary oocytes of mice. The frequency of chromosome aberrations was significantly higher in each X-irradiated group than that in control group with the tendency of increasing linearly with X-rays dose(Y=0.0091+0.1230 D), The frequency of centromere splits was also markedly higher in each irradiated group than that in control. In the dose range of 0-0.75 Gy, the dose-effect relationship was fitted well to linear equation, eg. Y=- 0.0002+ 0.0442 D. Using the frequency of chromatid aberrations in MⅡ, the risk of balanced translocations in the offspring were predicted to be 0.22% and 0.36% in the 0.75 and 1.00 Gy groups respectively.  
        关键词：Low dose;Mouse oocyte;Chromosome aberration;Carrier of the translocation   
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        发布时间：2024-11-05
      • Chen Shijie,Mo Suzhen,Zhang Hao,Le Ming,Li Yonghe,Jin Weiqiao
        Vol. 9, Issue 2, Pages: 83-85(1991)
        摘要：Male Wistar rats were exposed to 15 Gy single whole-body irradiation Blood samples collected at 24, 48 and 72h after irradiation. The results showed that in irradiated rats there were significant increases of α2M, αM, MDA, Cp and derease of SOD. No change of cathepsin D was found. The causes and significance of these changes are discussed.  
        关键词：Radiation;Macroglobulin;Malonaldehyde;Superoxide dismutase;Ceruloplasmin   
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        发布时间：2024-11-05
      • Bao Shiping,Shen Hengjia,Yao Liren
        Vol. 9, Issue 2, Pages: 86-89(1991)
        摘要：The micronucleus rates have been used as a biological end point, the relative biological effectiveness (RBE) of 125IUdR compared with 3HTdR were worked out on the basis of regression equations of dose-response calculated in this study. The results demonstrate that the total micronucleus rates and the micronucleus rates of cells increased with the increase of the rates of 125IUdR uptake respectively, the regressed equations were y1 = 0.895+0.029 x, y2=0.0776 +0.021 x. Similar results were also observed when 3HTdR was used, its regressed equations were y1= 0.082+0.0039 x, y2=0.068+0.003 x. The RBE of 125IUdR were 7.4 and 7 as compared with 3HTdR.These suggest that the radiotoxicity of 125IUdR is much more marked than that of 3HTdR. The advantages and disadvantages of 125IUdR used as trcer compared with those of 3HTdR were discussed finally.  
        关键词：125IUdR;3HTdR;Total micronucleus rates;Micronucleus rates of cells;The relative biological effectiveness (RBE) .   
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        发布时间：2024-11-05
      • Li Ximing,Shen Weiming,Liu Chengjie,Hu Xu
        Vol. 9, Issue 2, Pages: 90-94,78(1991)
        摘要：In order to minimize the toxic effect of chemotherapy of malignant tumors, the authors use a method of radiation indued cast polymerization of hydrophilic monomer at low temperature for immobilization the anticancer drug, 5-Fluorouracil, into the polymer matrix. The anticancer drug-polymer composite called slow release anticancer drug was used for treatment the transplantable squamous cell carcinoma in mice 615 and the transplantable sarcoma (S 180) in Kunming mice. There were marked difference between the treated group and the control group. That is the higher inhibition ratio and lower toxic effect were reported.  
        关键词：Anticancer drug;Slow release;Radiation polymerization   
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        发布时间：2024-11-05
      • Ding Lianzhong,Zhu Songmei,Gu Qiying,Zhu Yan
        Vol. 9, Issue 2, Pages: 95-98(1991)
        摘要：The total bacterial counts of commercially available the five spices powder and chilli were respectively found to be 103/g and 107/g, whereas the total fungal counts of both the five spices powder and chilli were about 104/g.The sterilization efficacy of spices irradiated by electron beam was studied in this paper. The effects of irradiation on the colours of spices were assessed by spectrophotometric analyzing aqueous extracts of spices. The content of water-insoluble volatile oils was determined in control and irradiated samples of spices by measuring the u. v. absorption. The effect of different packaging materials was discussed on total viable bacterial and fungal population in unirradiated and irradiated the five spices powder during storage at ambient temperature.  
        关键词：Irradiation;Electron beam;Sterilization;Chilli;The five spices powder   
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        发布时间：2024-11-05
      • Ding Li,Jin Yizun,Cai Rongmei,Shen Zhifen,Xu Liming,Yang jiakuan,Zheng Xiulong
        Vol. 9, Issue 2, Pages: 99-102(1991)
        摘要：In this paper,it reported the effect of a DNA repair inhibitor —ara-C on the recovery of plateau phase cultures of V79 cells from 60Co γ-rays induced potentially lethal damage (PLDR). The results showed the inhibition of PLDR, while treated with nontoxic dose (0.1 µg/ml) and ID20 (0.5 µg/ml) of ara-C for 2,4,6 hours following 10, 12Gy of irradiation, was not very effective. The repair inhibition factors (RIF) ranged from 1.15—1.83.  
        关键词：Ara-C;Potentially lethal damage recovery (PLDR);Repair inhibition factor (RIF);V79 cells   
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        发布时间：2024-11-05
      • Tao Feng,Zhu Shoupeng
        Vol. 9, Issue 2, Pages: 103-107(1991)
        摘要：In this paper, it is introduced that the internal radiation dose models of 147Pm in mouse organs have been estabished from the study on the metabolism of 147Pm. In terms of those models, we have calculated the dose rates and accumulated dose of corresponding organs at different times after 1.85×104Bq/g 147Pm was administrated from mouse tail vein.  
        关键词：Metabolism;Dose model;147 Pm   
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        发布时间：2024-11-05
      • Sun Jishan,Zhang Li,Zhang Zhiyi
        Vol. 9, Issue 2, Pages: 108-112(1991)
        摘要：Several properties, including absorption spectraactiveoxygen production and the rate of autocxidation of HA and its complexes with magnesium and zinc ions, were investigated and compared in this paper. New absorption peaks at 620 nm (Zn)and 628 nm (Mg) appeared in HA-Zn and HA-Mg complex solutions respectively, while the original peaks at 540 nm and 580 nm in HA solution reduced, or even though disappeared at higher molecular ratio of metal ion to HA. These phenomena suggested that the intra-hydrogen bond between carbonyl and hydroxyl groups of HA were replaced by bivalent cations. ESR data indicated that efficiency of both singlet oxygen and superoxide anion radical reduced significantly in the solution of HA complexes compared with that of HA. A simple test we designed proved the direct electron transfering from semiquinone radical of HA to oxygen. However, the formation of semiquinone radical of HA was inhibited by magnesium of zinc ions and then resulted in reduction of superoxide anion radicals. The rate constants of autooxidation of HA-Mg and HA-Zn complexes were 8.2 and 3.0 times bigger than that of HA.  
        关键词：Hypocrellin A;Primary photosensitizer-induced reaction;Active oxygens;ESR   
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        发布时间：2024-11-05
      • Sheng Huaiyu,He Yonghai,Chen Yaohuan,Tu Tiecheng,Dong Jirong
        Vol. 9, Issue 2, Pages: 113-117(1991)
        摘要：The present paper reports the synthesis and gamma-radiolysis of diphenyl 2,3, 4,5,6-D5 -phenylphosphonate, The deuterium concentration D% of the radiation products was determined by GC-MPES method, the probability of bondbreaking of C—P bond was 0.013, and of O—C bond was 0.987. The ESR spectra measured after γ-irradiation of DPPP samples at ambient temperature dominated by that for cyclohexadienyl-type radicals, while the spectra of low-temperature (77 K)irradiated DPPP were characteristic of phenyl radicals. The MS spectra of DPPP and d5-DPPP were measured and compared.  
        关键词：Diphenyl phenylphosphonate;Radiolysis;ESR;MS   
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        发布时间：2024-11-05
      • Zhang Wanxi,Wang Mouzhi,Sun Jiazhen
        Vol. 9, Issue 2, Pages: 118-125(1991)
        摘要：This paper extend application of the mathematical expectation to nonlinear crosslinking reaction of multi-composition systems. The relationship between reaction probability and some properties such as sol fraction were studied by the expectation method. The general conditions of gelation for the system were derived by summing and conditions of gelation up as a simple calculation of matrix in which every matrix element can be written directly, whose physics are clear and certain according to our expectation method.As a application of these results, we have derived average properties of di-composition polymer blend system and discussed relationship between the molecular weight() of sol as well as sol fraction and radiation dose, and relationship between gel fraction as well as gel point and compositions of the systems. The relationship between sol fraction and reaction probability for the blend system with the Flory distribution were established.  
        关键词：Radiation crosslinking of polymer blend;Relationship between sol fraction and radiation dose;Mathematical expectation theorems   
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        发布时间：2024-11-05
      • Wang Tiandiao,Li Binbin
        Vol. 9, Issue 2, Pages: 126-128(1991)
        摘要：The radiation colour change of pale blue and bluish beryls from Altay in Xinjang was studied with chemical composition analysis, crystal structure analysis, optical absorption behavior and electron spin resonance. It was shown that the colour of beryls only change into yellow by irradiation. This effect is attributed to the increase of Fe3+ in channel.  
        关键词：Beryl;Colour change   
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        发布时间：2024-11-05
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