最新刊期
      期 3 ， 1994
      • Zuo Zhihua,Yao Side,Li Hucheng,Jin Yizun,Lin Nianyun
        Vol. 12, Issue 3, Pages: 129-132(1994)
        摘要：One-electron reduction potential () is one of the important parameters of radiosensitive compound with high electron affinity. In this work one-electronr eduction potentials of some radiosensitizers such as Miso, 911, CMNa, SMU-1, SMU-2, SMD, SNN, S3 and BSO, were determined pulse radiolytically by using anthraquinone-2-sulfate (AQS), duroquinone (DQ) and methyl viologen(MV2+) as references.  
        关键词：Pulse radiolysis;Electron affinity;Radiosensitive compound;One-electron reduction potential   
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        发布时间：2023-04-23
      • Zhai Maolin,Yin Min,Ha Hongfei
        Vol. 12, Issue 3, Pages: 133-139(1994)
        摘要：In order to obtain the water-soluble, temperature sensitive polymer and activated copolymer, the radiation polymerizaton of N-isopropylacrylamide(NIPAAm), radiation copolymerization of NIPAAm and N-acryloxysuccide (NASI)in aqueous solution or in buffer solution (PBS pH=7.4) have been carried out by γ-rays from 60Co source at room temperature. The optimum dose range (1—7 kGy), dose rate (>40 Gy/min) and monomer concentration (1%) were chosen through determing the monomer conversion yield and molecular weight (Mw=6.8×105) of product. Synthesis of the reversible linear polymer was performed in tetrahydrofuran(THF) as well. In this way a white powder product could be obtained which possesses of thermally reversible property too, when it was dissolved in water or PBS. The only disadvantags of this method is that the molecular weight of the polymer produced in THF was much lower than that in aqueous solution.  
        关键词：N-isopropylacrylamide (NIPAAm);N-acryloxysuccinimide (NASI);Water-soluble;Temperature sensitive polymer   
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        发布时间：2023-04-23
      • Guo Fangqing,Gu Ruiqi
        Vol. 12, Issue 3, Pages: 140-145(1994)
        摘要：Enhancement of X-ray induced radiation damage in germinating wheat seeds by heat treatment (44℃ or 41℃, 20 min) has been investigated. The enhancement effect of heat treatment after irradiation was more significant than that of heat treatment before irradiation at dose range of 4.3-8.6 Gy. It was observed that germinating wheat seeds were very sensitive to heat treatment within 15 min after irradiation, which indicated that the repair of radiation damage was very active and rapid in a short period after irradiation. The repair of radiation damage in interval of fractionated irradiation was severely inhibited by heat treatment. The sensitivity of seeds to heat treatment corresponded with the levels of their repair activities. The more active the repairs of the seeds are, the more sensitive to heat treatment the seeds show. It was assumed that the enhancement of radiation damage by heat treatment in germinating wheat seeds was attributed to the inhibition of radiation damage repair by heat treatment, which is similar to the results of animal experiments.  
        关键词：Hyperthermia;X-ray;Micronuclei;Fractionated irradiation;Wheat   
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        发布时间：2023-04-23
      • Hu Fumin,Feng Wen,Qiu Jiaji
        Vol. 12, Issue 3, Pages: 146-150(1994)
        摘要：In this paper the mechanism of radiation crosslinking of polyvinyl chloride (PVC) and its changes of mechanical properties and thermostability have been discussed based on the changes of residual unsaturation of polyfunctional monomer and molecular weight of PVC sol during the radiation crosslinking of PVC. The disappearance of trapped free radicals in the XLPVC after aging has been explained by ESR spectrum.  
        关键词：Radiation crosslinking;Polyvinyl chloride;Polyfunctional monomer;Mechanical property;Molecular weight distribution;Trimethylolpropane trimethacrylate   
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        发布时间：2023-04-23
      • Wang Guiling,Wei Zengquan,Li Wenjian,Xie Hongmei
        Vol. 12, Issue 3, Pages: 151-154,145(1994)
        摘要：Projection range of 7 MeV/u 16O6+ ions implanted into CR-39 solid state track detector which is the material equivalent to biosamples is determined in the paper. Using measured data in the experiments, the projection range of the heavy ions in CR-39 (e. i. ion implantation depth) is analysed and discussed according to both etching rate ratio and statistics rule of residual range distribution. Results from the both ways are 32.5±6.2 µm and 30.5±6 µm respectively which are in agreement with each other well. The methods in the paper possess practical value to research on locating induced mutation in biosamples implanted by heavy ions.  
        关键词：CR-39 solid state track detector;Projection range;Surface etching rate;Radial etching rate;Axial direction etching rate   
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        发布时间：2023-04-23
      • Xu Yunshu,Mao Xingen,Guo Gaopin,Fu Yibei
        Vol. 12, Issue 3, Pages: 155-159(1994)
        摘要：The radiation crosslinking of ethylene-propylene copolymer containing trimethylolpropane trimethacrylate was investigated. Results showed that crosslinking density varied proportionally with dose and monomer contents, and the relationship between sol fraction and dose deviated from Charlesby-Pinner Equation. Based on statistical theory results, an assumption was suggested in and a semi-experimental formula was obtained which agreed well with experiments.  
        关键词：Ethylene-Propylene copolymer;Radiation crosslinking;Enhanlement effect;Polyfunctional monomer;Trimethylolpropane trimethacrylate   
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        发布时间：2023-04-23
      • Qi Shengchu,Zhang Xiangdong,Liu Wenjun
        Vol. 12, Issue 3, Pages: 160-163(1994)
        摘要：The ESR spectra of radicals induced by γ-irradiation in pig bone have been studied and comparised with those of UV-irradiated and unirradiated samples. An ESR signal which is specific for irradiation has been found. The signal height increased linearly with the increase of dose within the range of 1.23 to 6.24 kGy. When the samples were stored at room temperature and -18℃as well as in the presence of air for 45 days and 22 days respectively, the growth of signal height has been also observed.  
        关键词：ESR;Pig bone;Irradiated foods;Pork   
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        发布时间：2023-04-23
      • Ji Shouping,Fan Guocai,Wu Ying,Zhang Yangpei
        Vol. 12, Issue 3, Pages: 164-168(1994)
        摘要：By means of RFLPs method, the alterations of hprt gene structure in the mutant CHO-K 1 and HeLa MR cells induced by γ- exposure were examined in order to study the molecular mechanism of gene mutation induced by ionizing radiation: expression of hprt gene in CHO-K 1 mutant cells were also observed by Northern blot as well as slot blot. This experiment showed that ionizing radiation could result in hprt gene structure change which might lead to deficiency in mRNA transcription.  
        关键词：Ionizing radiation;HPRT gene;Mammalian cell;RFLPs   
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        发布时间：2023-04-23
      • Liu Weihong,Gong Shouliang,Li Xiuyi,Li Xinmin,Liu Shusheng
        Vol. 12, Issue 3, Pages: 169-173(1994)
        摘要：The present study was designed by ip panaxatroil (5 mg/0.2 ml•d × 14 d) 24 h before and after 5 Gy whole-body X-irradiation in male rats to observe the radioprotective effects of panaxatroil on opioid peptides and immune functions. The results showed that the hypothalamic opioid peptide contents and the immune parameters of thymus and spleen cells all decreased 14 d after irradiation, while hypothalamic opioid peptide contents approached the control level and all immune parameters decreased in irradiation plus panaxatroil group but higher than that in control group. The above results suggest that panaxatroil may alleviate the decrease of hypothalamic opioid peptide contents and immune parameters of thymus and spleen cells, and have radioprotective effects.  
        关键词：Panaxatroil;Radioprotection;Opioid peptides;Immune parameters   
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        发布时间：2023-04-23
      • Cong Xianling,Wang Xianli,Shu Qing
        Vol. 12, Issue 3, Pages: 174-178(1994)
        摘要：Male mice were hypodermically injected with human liver RNA, then exposed to 1.5 Gy X-radiation 7 hours or 24 hours later, the bone marrow cells were tested using the method of chromosome aberration. The results showed that human liver RNA could significantly reduce the frequencies of chromosome aberrations in bone marrow cells of mice 7 hours after exposed to 1.5 Gy X-rdiation. The best injection time of human liver RNA was 24 hours prior to irradiation and the best dose was 25 mg/kg. 25 mg/kg human liver RNA could also reduce the frequencies of chromosome aberrations in mice 24 hours after exposed to 1.5 Gy X-radiation. This function might be related to interferons induced by injection of human liver RNA.  
        关键词：Human liver RNA;X-radiation;Chromosome aberration;Antimutation   
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        发布时间：2023-04-23
      • Zhu Shoupeng,Chu Xianxiang,Wang Guolin
        Vol. 12, Issue 3, Pages: 179-185(1994)
        摘要：The dynamic of the whole body retention in rats after iv 75Semethionine was determined by whole body counting. The retantion was well described by a three-component equation: R (t)=24.06 e-0.679t+41.24 e-0.042t+15.41 e-0.005t wherein the t1/2 were T1=1.0 d, T2=16.4d,T3=132 d. The radioactivities in urine revealed 2 components with t1/2=0.6 and 9.8 d respectively. Biological t1/2=5.2 d in fecal excretion for the fast component and 13.2 d for the long term component. The autoradiographic study indicated that after iv 75Se-methionine in rats the radioactivity accumulated chiefly in pancreas, and then in liver, skeleton and thyroid gland, only a trace was found in hair. A method was studied for rapid preparation of autoradiographs for tissue slices by impregnation of nuclear emulsion with liquid scintillators PPO and POPOP. Mixing liquid scintillators, especially a hydrophilic dioxane solvent, with emulsion allowed also rapid autoradiographic grain production. The tissue distribution of 75Se-methionine by fluorescence-sensitized autoradiography was observed after iv 75Se-methionine. The number of autoradiographic grains/10 µm2 was increased with the scintillator by 4—10 times. The silver grains in the autoradiograms were distributed high in the pancreatic acini and the islets, and then in liver cells, bone marrow and epithelial cells of thyroid gland.  
        关键词：Radioactive tracing;75Se-methionine;Whole body level;Organ level;Cell level;Retention   
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        发布时间：2023-04-23
      • Wang Ping,Piao Xianggen,Cai Lu
        Vol. 12, Issue 3, Pages: 186-188,192(1994)
        摘要：The male mice were irradiated in whole-body to chronic γ-radiation or X-ray fractional radiation (D1). D2 (1.5Gy X-rays) was given 40 days after exposure to D1. The effect of chronic or fractional pre-exposure of low dose radiation on the chromosome damage induced by subsequently high dose irradiation was observed. The results showed that the adaptive response could be induced by low dose chronic or fractional radiations in male mice germ cells.  
        关键词：Adaptive response;Germ cell;Chromosome aberration;Low dose radiation   
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        发布时间：2023-04-23
      • Min Rui,Cheng Tianmin,Luo Chengji,Chen Qi,Din Zhenhai,Mon Xiangshun
        Vol. 12, Issue 3, Pages: 189-192(1994)
        摘要：Peripheral blood mononuclear cells from normal persons were irradiated by 1—6 Gy γ-rays in vitro. NK activity was determined by means of 3H-TdR releasing and CD57 positive cells were counted by means of immunocytochemistry, respectively. The results showed that NK cell activity changed unobviously whthin 2 Gy irradiation dose and dropped gradually with increasing irradiation dose and was distinguished lower than that of control when irradiation dose increased to 6 Gy. NK cell activity changed with time and was lowest at 12 hours after irradiation, then it restored gradually. The restoring level of NK cell activity was related to irradiation dose. The number of NK cell had little change till 6 Gy irradiation. The activity of NK cell increased significantly when irradiated cells were stimulated with IL-2.  
        关键词：Irradiation;NK cell;Immunocytochemistry   
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        发布时间：2023-04-23
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