摘要:The cell survival curve of the CFU-f in the guinea-pig bone marrow, which is distinguished according to the cellular density of colony, is assayed. By the analysis of the relative data from the experiment and the observation of the morphology of colony, we have proved that there are two distinct subpopulations in radiosensitivity and colonial morphology among the CFU-f populations in the guinea-pig bone marrow. The dense cellular colony type subpopulation of the CFU-f:D0=2.17 Gy, N=1.14; the sparse cellular colony type subpopulation of the CFU-f:D0=4.09 Gy, N=1.13. The studies may have important implication in acquiring a better understanding of the characteristics of the radiation biology as well as the rule of the radiation injury and recovery of the CFU-f.
摘要:The effect of radiation crosslinking on the structure and properties of PE-NBR multiple phase system was studied in this paper. We have demonstrated the adaptability of equation (1) and the relationship of sol fraction and irradiated dose to multiplephase system.
关键词:Radiation crosslinking;Multiplephase system;Nitrile rubber;Crystability;Melting point
摘要:In a capacitively coupled discharge with external electrodes, hexamethylcyclotrisiloxane (D3) was polymerized in the presence of ammonia or nitrogen. The polymer structure was investigated by IR spectroscopy and XPS, and properties of the polymer were studied by TG analysis and contact angle detection. The results show that both N2 and NH3 participated into reaction and eventually incorporated into polymer structure mainly in the form of C=NH, and the N/Si ratio increased with increasing NH3 concentration in the D3/NH3 mixture. The polymeric films prepared in NH3 are possessed of good hydrophobicity.
关键词:Plasma polymerization of hexamethylcyclotrisiloxane;Contact angle of plasma polymerized hexamethylcyclotrisiloxane
摘要:This paper gave the experimental results with regard to the effect of radiation on the white wax scale seeds treated with 241Am-Be neutron source. After being irradiated with the dosage of 7.62×104, 3.1×105 and 1.24×106n/cm2, respectively both the duration and quantities of white wax secreted by the male larva of the white wax scale are incresed greatly. The average output is heiger than those of the control.
摘要:The structures and crystallization behavior of polytetrafluoroethylene (PTFE) were studied with electronoptical microscope, electron diffraction and differential scanning calorimetry (DSC) techniques respectively. It was shown that the morphology of PTFE depends not only on the radiation intensity, but also on crystalline perfectness of PTFE. The irradiated PTFE had five kinds of typical structure morphology including to the surface crystals, needle-like + spherulite, rodlike, single crystals and spheric particles. These results were correlated with DSC crystallization curves very well.From electron pattern it is demonstrated that in these irradiated crystals there exists some ordered regions, which act as nucleus of crystal. This indicated that within some range of dose, the inhomogenous distribution of irradiation of the same crystal, enables a perfect crystal lattice to have higher resistance to γ irradiation.
摘要:The radiation graft copolymer of styrene onto MgO has been characterized by FT-IR, X - ray diffaction, XPS and GPC. It is shown that the graft copolymer has some peaks of MgO and polystyrene in IR and X - ray diffraction spectra respectively. It was found that there were some at 285.0, 530.0 and 87.6 eV in the spectra of the blend, which blongs to C1S, O1S and Mg2S respectively, while the peak position of C1S, O1S and Mg2S of the MgO - g-styrene copolymer were 284.0, 531.7 and 88.4 eV respectively. This shows that the active centers caused by the defect of Mg atom after irradiation react with styrene to form monomer free radical, then grafting reaction occurs by the free radical mechanism. The ratio of oxygen to carbon (O/C) of graft products decreases with the increasing of the grafting yield. The molecular weight of graft copolymer is higher than that of homo-polymer, but the molecular weight distribution is broader in the graft copolymer.
摘要:It is well known that small amount of mineral acid gave a obvious enhancement to radiation grafting yields for some typical systems such as the grafting copolymerization of styrene in methanol onto polyethylene, polypropylene and other polyolefins. But in the case of segmented polyetherurethane as the matrix, the radiation grafting yield of N-vinyl-2-pyrrolidone on it would be optimum only in basic media.In this investigation the radiation grafting copolymerizations with some monomers such as acrylamide, acrylic acid, 4-vinyl-pyridine and styrene were performed. The radiation grafting efficiencies of these systems were shown to be enhanced as well in the grafting systems with higher pH values. Primary explanation was given.
Li Ximing,Yuan Zhijian,Chen Wenming,Gu Baoming,Jiang Xintian
Vol. 7, Issue 3, Pages: 36-40,9(1989)
摘要:The controlled release anticancer drug-copolymer composites were made by radiation-induced copolymerization at low temperature. The release rate and amount of drug can be controlled by regulating the content of bydrophilic or hydro phobic monomer and cross-linking reagent in drug-copolymer composite and by changing the radiation dose and drug content. The pore structure of composite may be promote the release rate. The diffuse mechanisms of drug were discussed.
摘要:A new antitumour agent of diketopiperazine derivative, dl-1,2-bis(4-morpholinemethyl-3,5-dioxopiperazin-l-yl)propane (AT 2153, MST-02) was synthesized by Y. F. Ren et al[1]. It exhibited significant activities against several kinds of cancer and radiopotentiating effect on Sarcoma S 37 in mice.The radiosensitizing effect of AT 2153 was studied with hypoxic Human Lung Adeno-carcinoma cell line SPC-A-1 in vitro. Using colony-forming technique, its SER is 1.22 at the concentration of 0.10 m mol dm-3, and the C 1.6 is 0.29 m mol dm-3. It might be a potent radiosensitizer.
摘要:The kinetics of inverse emulsion polymerization of sodium acrylate solution has been studied at 23-39℃ with Cobalt-60 Gamma initiation dilatometrically. The conversion-time curves are generally S-shaped. For maximum rate of polymerization, the following kinetic expression has been determined for the conditions investigated:The overall activation energy for polvmerization rate(Ea) is (16.7 kJ/mol)(23-39℃). The effects of dose rate, monomer concentration and emulsifier concentration on molecular weights of pdymers have been examined. Discussions on nucleation mechanism and kinetics have been taken.
摘要:Thrombopoiesis after a single dose of 2,4,6,8 and 10 Gy gamma-ray total body irradiation was studied by means of 35S incorporation technique in mice. It was found that the post irradiation change of thrombopoietic activity ran a polyphasic course. The thrombopoiesis was stimulated 2 days after irradiation except in the 10 Gy group. The time of onset of declination, the nadir and the speed of recovery of thrombopoiesis were correlated with the dose of irradiation. Meanwhile, the slope of declination was independent of the dose, and the nadir was reached arround the 8 th post irradiation day in all dose groups. Thrombopoiesis could recover to normal level spontaneously within the dose range up to 8 Gy. An overstimulation of thrombopoiesis was seen in the recovery phase after 2-6 Gy irradiation, followed by a depressive phase. The peripheral platelet count followed a similar course as the thrombopoietic activity, with a smaller range of variation. The relationship between thrombopoiesis and peripheral platelet count and the characteristics of the change of thrombopoiesis following different doses of irradiation are discussed.
摘要:In this paper we described a modified fluorometric analysis of DNA unwindingg method for the detection of DNA strand breaks in cells. Some factors which might influence the results were also investigated, and the effect of oxygen on the induction of DNA strand breaks and its repair in γ-irradiated mammalian cells was observed. It was shown that a liner relationship existed between the dose and the extent of DNA damage. OER of L7712 cells was 3.0. while OER of 3T3 cells were 1.37 and 1.01 under two different irradiation conditions. The differences between them were an interested and significant question. Incubated at 37℃ under oxic condition, the hypoxically irradiated 3T3 cells rejoined their strand breaks more rapidly and efficiently than the oxically irradiated cells did. Post-irradiation hypoxia could inhibit the rejoining of strand breaks in the hypoxically irradiated 3T3 cells.
关键词:Fluorometric analysis of DNA unwinding;Oxygen effect;DNA strand breaks and its rejoining
摘要:The effect of ionizing irradiation on erythrocyte purine nucleoside phosphorylase and erythrocyte membrane lipid peroxidation have been comparatively studied in vitro and in vivo.After irradiation of the heparinized rat blood with 0,10,50, and 100 Gy and during the different days following the whole-body exposure to 8.5 Gy, PNP activities decreased whereas erythrocyte membrane lipid peroxidation increased. These results are seemly shown the relationship existing between erythrocyte PNP activity and membrane lipid peroxidation.
关键词:Radiation in vitro;Whole-body irradiation;Erythrocyte purine nucleoside phosphorylase;Lipid peroxidation