摘要:Polytetrafluoroethylene (PTFE) has always been regarded as a typical kind of radiation degradation polymer. But,in fact, PTFE can be induced crosslinking by γ-ray or electron beam at some special conditions (free oxygen and a narrow temperature region at 335±5 ℃) . Compared with radiation degradation PTFE, cosslinking PTFE owns a lot of new properties. Some articles concerning with these have been published, which will be systematically reviewed in this.
DENG Huachuan,ZHANG Shuying,ZHANG Runqing,PEN Zhijun,ZHOU Dezhong,YANG Qilin
Vol. 17, Issue 1, Pages: 15-18(1999)
摘要:This paper presents a study on the radiation corsslinking modification of high-density polyethylene (HDPE) filament by 60Co γ-ray. The HDPE filament netted with fibre glass is middle lamella and quality key of reinforced heat shrinkables. Our study are modifying the HDPE filaments by 60Co γ-ray with the four atmospheres (in air, partial air; inert gases and vacuum) at room temperature and observing their relevant propeties. The optimal irradiation condition has been obtained. That is kind of inert atmosphere. In inert atmosphere radiation crosslinking doesn't depend on the dose rate study choose, but primarily on the absorbed dose. The influences of absorbed dose and irradiation condition on the gel fraction and tensile strength have been examined. The material heat resistance and heat shrinkable ability was considerably improved with almost no change on its mechanical strength. The radiation modification filament was successfully used in reinforce heat shrinkables and can meet completely the requirements of the reinforced heat shrinkable materials.
摘要:Nanocrystalline nickel powders were prepared by irradiating the aqueous solution of NiSO4 with γ-ray, using AgNO3 as nucleation agent. It was found that the pH value of the system before irradiation affected the composition of products and alkalinity of solution was necessary to prepare nickel nanopowders. The characterization of products with transmission electron microscope (TEM) and X-ray photoelectron spectrum (XPS) indicated that the powders were fibrelike nickel particles (diameter <10nm) . Metallic silver, as crystal nucleus,was wrapped up in metallic nickel. The existence of AgNO3 not only supplied the aggregation center, but also affected the micromorphology of products.
摘要:The effect of heavy ion 12C6+ (1.656×104 Gy) and 16O8+ (1.585x107 Gy) irradiation on olaquindox has been investigated. The result indicated that after 12C6+,16O8+ irradiation and structure of more than 15% olaquindox was changed. The characteristic absorption peaks at 266nm, 382nm became flatter and lower,indicating decrease of olaquindox content,however its antibacteria effect was enhanced apparently. In addition several irradiation products was yielded.
摘要:Polymer-drugs composite with long periods of controlled slow release was made by radiation induced polymerization in room temperature. In experiment in vivo, the composite were implanted subcutaneously the back of rabbits. The concentration of 1- (2-tetrahydrofuryl) -5-fluorouracil (FT-207) was determined by HPLC. The results of test showed that the concentration of serum drug is 1.0µg/mL after 1 week in the polymer-drug composites group. The drug concentration of tissue surrouding the composites is 76.2±10.4µg/mL. The drug concentration in the far organ (e.g.the lung 1.2±0.5µg/mL) is lower than the tissue surrounding the composite. The serum drug is higher and shorter time by the routine methods. The serum concentration of FT-207 is lower and retarded by implanted.
摘要:To explore the characteristics of intestinal mucosal immunity after radiation injury,IEL number, proliferation activity,cytotoxic activity as well as the TNF-α and TGF-β concentrations of supernatant of cultured IEL were studied using IEL freshly isolated from whole small intestine of Kunmimg strain mice received 3Gy total body 60Co γ-ray irradiation. The proliferation activity, cytotoxic activity as well as the number of IEL in small intestinal mucosa were significantly decreased at 8h post-irradiation, reaching lowest level at 72h. The TNF-α and TGF-β concentrations of supernatant of cultured IEL isolated from irradiated mice were elevated at 8h, reaching peak at 72h. That the decrease in number and functions of IEL may play an important role in the damage intestinal mucosal immunity barrier after total body irradiation.
摘要:Inhibitory effects of interferon-γ (γ-INF) and dexamethasone (Dexa) on growth of cultured fibroblasts were observed by MTT colorimetry, silver colloid technique of nucleolar of orgnizer regions associated protein (AgNORs) combined with image analysis and immunohistochemistry for type III collagen. The results showed that, (1) when γ-INF of 250×103U/L and Dexa of 100mg/L were used, the inhibitory percentages of them on normal fibroblasts 3 days after culture were 43% and 33% respectively; (2) Above mentioned two inhibitors showed evident inhibitory effects on proliferation of normal, irradiated (on 3 or 5 days after irradiation) and 5-HT stimulated fibroblasts; (3) The third day after culture, the strongest inhibitory effects on fibroblasts AgNORs were observed when 250×103U/L of γ-INF and 150mg/L of Dexa were delivered, the number of AgNORs granules in 5-HT stimulated fibroblasts decreased to 58% and 56% of normal control values; while the mean values of three quantitative parameters of AgNORs were also lower than those of control values; (4) The two inhibitors of above mentioned concentrations also demonstrated obvious restrained effect on the synthesis of type III collagen in 5-HT stimulated fibroblasts on day 3 after culture, the percentage of type III collagen positive fibroblasts were about 62% and 43% of control values.
关键词:Interferon-γ;Dexamethasone;Fibroblasts;5-Hydroxytraptamine;Irradiation;Type III collagen;Proliferation inhibition
摘要:Attempts were afforded to search for new antiaplastic anemia drays from tetrapyrroles. Observation of the effects of copper purpurin 18, a representative one of the metal tetrapyrroles was synthesized by ours, on erythropoiesis in Kungming mice lethally irradiated. It was shown that copper purpurin18 preferably increased stem cells (CFU-S) into erythroidpregenitor cells (CFU-E) ,and increase WBC and nucleated cells of bone marrow significantly in the phase of recover. It suggested that there may be good prospect in developing new drugs for treatment of aplastic anemia with copper purpurin 18,and it was worth to further investigations.
摘要:According to the method established previously, the osteoclasts were released and then settled on to glass slides. The numbers of apoptotic osteoclasts after in vitro γ-irradiation (0.5,1,3, 5 Gy) were measured by fluorescence staining assay. The results are that control samples and samples irradiated at 0.5 Gy could be distinguished in a statistically significant way. This suggests that osteoclasts are sensitive to irradiation and low doses can induce apoptosis. Furthermore, the percentage of apoptotic cells at 3 Gy reached the peak, this could be provided as a model for studying the molecular mechanism of apoptosis.
SU Xu,LUO Can,FU Shibo,LIU Jianxiang,JU Guizhi,LIU Shuzheng
Vol. 17, Issue 1, Pages: 48-51(1999)
摘要:To elucidate the possible mechanism of immunoenhancement after low dose radiation (LDR) . The regular of changes of IL-2Rα expression in splenocyte following low dose irradiation was studied. IL-2R expression was induced by Con A in vitro 24 hours after whole-body irradiation (WBI) . The expression of IL-2R in splenocyte was analyzed by direct immunofluorescence flow cytometry. It was found that the expression of IL-2R in splenocyte was shown significantly increased (p <0.05) 24 hours after WBI with doses of 50~500mGy, in which the percentage of CD25 positive cells was significant higher than that in sham irradiated group, and the highest was in irradiated group with 50mGy (p <0.01) . The percentage of CD25 positive cells did not change significantly after WBI with 1.0~2.0Gy (p>0.05) . However, the percentage of CD25 positive cells decreased significantly after WBI with 4.0~6.0Gy (p <0.05, p <0.01 respectively) . The results indicate that LDR might enhance and stimulate the expression of IL-2R in splenocyte. The results are important to elucidate the mechanism of immunoenhancement after low dose radiation. The results following WBI with higher doses suggested that WBI with higher doses might suppress the expression of IL-2R in splenocytes.
摘要:Composition and manufacturing technology of low-smoke, halogen-free and flameresistant heat-shrinkable cable accessories have bee studied. The products include insulating pipes, outer-jackts and branch pipes. Halogen content of pipe products well meets IEC 754-1. Smoke density of pipe products well meets ASTM E 662,the performance of the pipe products well meets DL413-91 standards of technical requirements of application of 35kV heat-shrinkable cable accessiories, and the performance of all the products well meets the Chinese GB 11033-89 Nationol standards of basic technical requirements on 26/35kV cable accessories.
摘要:In this article, some critira related to processing technology for inhibiting Germination of garlic by irradiation are discussed and reviewed. The result shows that the following irradiation rules are suitable for Chinese garlic: (1) irradiation period is better before August 10, and no later than August 20. (2) Suitable total dose ranges from 50 to 100 Gy. (3) The nonuniformity of irradiation dose is no more than 2.
LIU Dantao,ZHENG Zheng,SHI Ning,QI Chengyun,MA Guangcun
Vol. 17, Issue 1, Pages: 61-63(1999)
摘要:Use only once narcotization units were sterilized by 60Co γ-ray irradiation. According to the result of several years application the products that were irradiated with 10kGy 60Co γ-ray was up to the standard (10-6 SAL) . No infection has been found after for about 100,000 applications.
关键词:Used only once;Narcotization unit;Irradiation sterilization
摘要:In order to obtain a more ideal hydrogel wound dressing, PEO graft hydrogcl films formed by electron bcam(EB) irradiation of the aqueous solutions of poly(ethylene oxide)(PEO) incorporated with poly (vinyl alcohol) (PVA) at different ratio were prepared, and their physiochemical properties were investigated as a function of production factors combination. The experimental results showed that gel fraction of the PEO graft hydrogel films depended mainly on irradiation dose and concentration of the polymers. Their degree of swelling was intimately related to irradiation dose, concentration, blending ratio and molecular weight of the polymers. Their tensile strength and elongation at break were obviously dependent on irradiation dose and blending ratio of the polymers. It is found that a new PEO E-30 graft hydrogel film of 20 wt% at a ratio of 7:3 has better physiochemical properties such as flexibility, moderate gel fraction, degree of swelling and clougation at break, especially its higher tensile strength than other PEO graft hydrogel films or pure PEO E-30 hydrogel film. These results indicated that PVA can improve the mechanical strength of the PEO E-30 hydrogel film through reducing the degree of swelling of the PEO E-30 hydrogel film after the irradiation graft.
MA Janhua,LIN Wezheng,WANG Wenfeng,YAO Side,LIN Nianyun
Vol. 17, Issue 1, Pages: 52-53(1999)
摘要:Our previous work dealing with transient laser spectroscopy and kinetics of DNA have offered time resolved evidence for electron transfer modification of DNA at guanine moiety by triplet acetone(Ace*)[1]. However observation of radical ion pair resulting from electron transfer oxidation of DNA by planar aromatic photonuclease is hampered by the failure of direct observation of radical cation of DNA[2,3].
关键词:DNA;Nucleotide;Anthraquinone-2-sulfonate triplet state;Radical ion pair;Transient laser spectroscopy;Electron transfer oxidation